Zobrazeno 1 - 10
of 186
pro vyhledávání: '"René P, Zahedi"'
Autor:
Darren M. Blackburn, Korin Sahinyan, Aldo Hernández-Corchado, Felicia Lazure, Vincent Richard, Laura Raco, Gabrielle Perron, René P. Zahedi, Christoph H. Borchers, Christoph Lepper, Hiroshi Kawabe, Arezu Jahani-Asl, Hamed S. Najafabadi, Vahab D. Soleimani
Publikováno v:
iScience, Vol 27, Iss 7, Pp 110241- (2024)
Summary: Adult stem cells play a critical role in tissue repair and maintenance. In tissues with slow turnover, including skeletal muscle, these cells are maintained in a mitotically quiescent state yet remain poised to re-enter the cell cycle to rep
Externí odkaz:
https://doaj.org/article/aed6cff8a4964cb88e74903bb70434c9
Publikováno v:
Computational and Structural Biotechnology Journal, Vol 21, Iss , Pp 2446-2453 (2023)
Peptide retention time (RT) prediction algorithms are tools to study and identify the physicochemical properties that drive the peptide-sorbent interaction. Traditional RT algorithms use multiple linear regression with manually curated parameters to
Externí odkaz:
https://doaj.org/article/27173e3595d34ec496124f6ef3f9257e
Autor:
Johanna P. van Geffen, Frauke Swieringa, Kim van Kuijk, Bibian M. E. Tullemans, Fiorella A. Solari, Bing Peng, Kenneth J. Clemetson, Richard W. Farndale, Ludwig J. Dubois, Albert Sickmann, René P. Zahedi, Robert Ahrends, Erik A. L. Biessen, Judith C. Sluimer, Johan W. M. Heemskerk, Marijke J. E. Kuijpers
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-17 (2020)
Abstract Hyperlipidemia is a well-established risk factor for cardiovascular diseases. Millions of people worldwide display mildly elevated levels of plasma lipids and cholesterol linked to diet and life-style. While the prothrombotic risk of severe
Externí odkaz:
https://doaj.org/article/1989a910cf91487588230cb6fcebb5c1
Autor:
Tamara Scheidt, Oliver Alka, Humberto Gonczarowska-Jorge, Wolfgang Gruber, Florian Rathje, Margherita Dell’Aica, Marc Rurik, Oliver Kohlbacher, René P. Zahedi, Fritz Aberger, Christian G. Huber
Publikováno v:
Cell Communication and Signaling, Vol 18, Iss 1, Pp 1-18 (2020)
Abstract Background Aberrant hedgehog (HH) signaling is implicated in the development of various cancer entities such as medulloblastoma. Activation of GLI transcription factors was revealed as the driving force upon pathway activation. Increased pho
Externí odkaz:
https://doaj.org/article/274b593e3c1b42f79ca06a9c78081fdb
Autor:
Julia Grimmer, Stefan Helm, Dirk Dobritzsch, Gerd Hause, Gerta Shema, René P. Zahedi, Sacha Baginsky
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Most chloroplast proteins are imported from the cytosol and thus transiently exposed to the cytosolic proteasome. Here the authors show that impairment of the cytosolic proteasome can elevate precursor protein abundance and photosynthetic activity su
Externí odkaz:
https://doaj.org/article/69490422533c4a51abd07417825ad799
Autor:
Ruzanna Mnatsakanyan, Stavroula Markoutsa, Kim Walbrunn, Andreas Roos, Steven H. L. Verhelst, René P. Zahedi
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-12 (2019)
Reversible cysteine modifications play important roles in cellular redox signaling. Here, the authors develop a chemical proteomics strategy that enables the quantitative analysis of endogenous cysteine nitrosylation sites and their dynamic regulatio
Externí odkaz:
https://doaj.org/article/a46b2f4d4dac4cac9faa09918943bfac
Autor:
Giselle Villa Flor Brunoro, Paulo Costa Carvalho, Valmir C. Barbosa, Dante Pagnoncelli, Claudia Vitória De Moura Gallo, Jonas Perales, René Peiman Zahedi, Richard Hemmi Valente, Ana Gisele da Costa Neves-Ferreira
Publikováno v:
BMC Cancer, Vol 19, Iss 1, Pp 1-12 (2019)
Abstract Background Worldwide, breast cancer is the main cause of cancer mortality in women. Most cases originate in mammary ductal cells that produce the nipple aspirate fluid (NAF). In cancer patients, this secretome contains proteins associated wi
Externí odkaz:
https://doaj.org/article/9c79487450214d43929c6291f103493a
Autor:
Anne-Katrin Guettsches, Nancy Meyer, René P. Zahedi, Teresinha Evangelista, Thomas Muentefering, Tobias Ruck, Emmanuelle Lacene, Christoph Heute, Humberto Gonczarowska-Jorge, Benedikt Schoser, Sabine Krause, Andreas Hentschel, Matthias Vorgerd, Andreas Roos
Publikováno v:
Biomedicines, Vol 10, Iss 10, p 2443 (2022)
Dominant VCP–mutations cause a variety of neurological manifestations including inclusion body myopathy with early–onset Paget disease and frontotemporal dementia 1 (IBMPFD). VCP encodes a ubiquitously expressed multifunctional protein that is a
Externí odkaz:
https://doaj.org/article/01e33abb37a14f4589274c424ffffc0e
Autor:
José Andrés González Coraspe, Joachim Weis, Mary E. Anderson, Ute Münchberg, Kristina Lorenz, Stephan Buchkremer, Stephanie Carr, René Peiman Zahedi, Eva Brauers, Hannah Michels, Yoshihide Sunada, Hanns Lochmüller, Kevin P. Campbell, Erik Freier, Denisa Hathazi, Andreas Roos
Publikováno v:
Skeletal Muscle, Vol 8, Iss 1, Pp 1-19 (2018)
Abstract Background Caveolin-3 (CAV3) is a muscle-specific protein localized to the sarcolemma. It was suggested that CAV3 is involved in the connection between the extracellular matrix (ECM) and the cytoskeleton. Caveolinopathies often go along with
Externí odkaz:
https://doaj.org/article/6d998471d66f4de781e502ffc59dcddf
Autor:
F.-Nora Vögtle, Julia M. Burkhart, Humberto Gonczarowska-Jorge, Cansu Kücükköse, Asli Aras Taskin, Dominik Kopczynski, Robert Ahrends, Dirk Mossmann, Albert Sickmann, René P. Zahedi, Chris Meisinger
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-10 (2017)
Protein localization plays an important role in the regulation of cellular physiology. Here the authors use an integrated proteomics approach to localize proteins to the mitochondria and provide a detailed map of their specific localization within th
Externí odkaz:
https://doaj.org/article/e4addab5f93948baa7c80f0bca3fc0ce