Zobrazeno 1 - 6
of 6
pro vyhledávání: '"René Overmeer"'
Autor:
Lidwien P. Smabers, Emerens Wensink, Carla S. Verissimo, Esmee Koedoot, Katerina-Chara Pitsa, Maarten A. Huismans, Celia Higuera Barón, Mayke Doorn, Liselot B. Valkenburg-van Iersel, Geert A. Cirkel, Anneta Brousali, René Overmeer, Miriam Koopman, Manon N. Braat, Bas Penning de Vries, Sjoerd G. Elias, Robert G. Vries, Onno Kranenburg, Sylvia F. Boj, Jeanine M. Roodhart
Publikováno v:
Journal of Experimental & Clinical Cancer Research, Vol 43, Iss 1, Pp 1-16 (2024)
Abstract Background The inability to predict treatment response of colorectal cancer patients results in unnecessary toxicity, decreased efficacy and survival. Response testing on patient-derived organoids (PDOs) is a promising biomarker for treatmen
Externí odkaz:
https://doaj.org/article/42108938a8624e94af5a5620f30c1743
Autor:
Stephanie Kourula, Merel Derksen, Ferran Jardi, Sophie Jonkers, Marjolein van Heerden, Peter Verboven, Veronique Theuns, Stijn Van Asten, Tinne Huybrechts, Annett Kunze, Ewa Frazer-Mendelewska, Ka Wai Lai, René Overmeer, Jamie Lee Roos, Robert G.J. Vries, Sylvia F. Boj, Mario Monshouwer, Farzin Pourfarzad, Jan Snoeys
Publikováno v:
European Journal of Pharmaceutical Sciences. :106481
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1ff41ba60f7d0e6a9dd68fb5df1bd0f7
https://doi.org/10.1016/j.ejps.2023.106481
https://doi.org/10.1016/j.ejps.2023.106481
Autor:
Esmee Koedoot, Inez van Weersch, Gakuro Harada, Masahiko Watanabe, Hamdy Warda, Hideaki Kyan, Yasmine Abouleila, Takahiko Kumagai, Yuichi Hikichi, René Overmeer, Jeanine Roodhart, Kiyotaka Matsuno, Carla Verissimo, Sylvia F. Boj
Publikováno v:
Cancer Research. 83:157-157
Colorectal cancer (CRC) is the third leading cause of cancer and cancer-related death. A large fraction of the CRC patients diagnosed with de novo metastatic disease do not benefit from standard of care and experience substantial side effects. Theref
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24410ba3b26fd9bbc48ac426abfc0969
https://doi.org/10.1158/1538-7445.am2023-157
https://doi.org/10.1158/1538-7445.am2023-157
Autor:
Carla S. Verissimo, Lidwien Smabers, Emerens Wensink, Esmee Koedoot, Maarten Huismans, Celia Higuera Barón, Ricardo Korporaal, Emma Teal, Katerina-Chara Pitsa, Edwin van Oosten, Roshni Nair, Liselot Valkenburg, Geert Cirkel, Anneta Brousali, Jorieke Salij, René Overmeer, Manon Braat, Sjoerd Elias, Robert Vries, Onno Kranenburg, Miriam Koopman, Sylvia F. Boj, Jeanine Roodhart
Publikováno v:
Cancer Research. 82:4112-4112
Colorectal cancer (CRC) is the third leading cause of cancer and cancer-related death. A large fraction of the CRC patients diagnosed with de novo metastatic disease do not benefit from the standard of care but still experience substantial side effec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3ed98379a73a6522c0128343181524ee
https://doi.org/10.1158/1538-7445.am2022-4112
https://doi.org/10.1158/1538-7445.am2022-4112
Autor:
Renske D.M. Steenbergen, Saskia M. Wilting, Peter J.F. Snijders, Florianne E. Henken, Akihiko Ito, Johannes Berkhof, Daniëlle A.M. Heideman, René Overmeer, Yoshinori Murakami, Theo J.M. Helmerhorst, Chris J.L.M. Meijer, Debbie Claassen-Kramer
Publikováno v:
Journal of Pathology, 215(4), 388-397. John Wiley & Sons Ltd.
Journal of Pathology, 215(4), 388-397. John Wiley and Sons Ltd
Overmeer, R M, Henken, F E, Snijders, P J F, Claassen-Kramer, D, Berkhof, J, Helmerhorst, TJ, Heideman, D A M, Wilting, S M, Murakami, Y, Ito, A, Meijer, C J L M & Steenbergen, R D M 2008, ' Association between dense CADM1 promoter methylation and reduced protein expression in high-grade CIN and cervical SCC ', Journal of Pathology, vol. 215, no. 4, pp. 388-397 . https://doi.org/10.1002/path.2367
Journal of Pathology, 215(4), 388-397. John Wiley and Sons Ltd
Overmeer, R M, Henken, F E, Snijders, P J F, Claassen-Kramer, D, Berkhof, J, Helmerhorst, TJ, Heideman, D A M, Wilting, S M, Murakami, Y, Ito, A, Meijer, C J L M & Steenbergen, R D M 2008, ' Association between dense CADM1 promoter methylation and reduced protein expression in high-grade CIN and cervical SCC ', Journal of Pathology, vol. 215, no. 4, pp. 388-397 . https://doi.org/10.1002/path.2367
We previously showed that silencing of TSLC1 recently renamed CADM1, is functionally involved in high-risk HPV-mediated cervical carcinogenesis. CADM1 silencing often results from promoter methylation. Here, we determined the extent of CADM1 promoter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e614da7ecc809d78a02fb0bf22509fb
https://doi.org/10.1002/path.2367
https://doi.org/10.1002/path.2367
Autor:
Sander Mertens, Maarten A. Huismans, Carla S. Verissimo, Bas Ponsioen, Rene Overmeer, Natalie Proost, Olaf van Tellingen, Marieke van de Ven, Harry Begthel, Sylvia F. Boj, Hans Clevers, Jeanine M.L. Roodhart, Johannes L. Bos, Hugo J.G. Snippert
Publikováno v:
Cell Reports, Vol 42, Iss 4, Pp 112324- (2023)
Summary: Patient-derived organoids (PDOs) are widely heralded as a drug-screening platform to develop new anti-cancer therapies. Here, we use a drug-repurposing library to screen PDOs of colorectal cancer (CRC) to identify hidden vulnerabilities with
Externí odkaz:
https://doaj.org/article/90d447bcda174d4aba2b71aaf83d4fbd