Zobrazeno 1 - 10
of 17
pro vyhledávání: '"René Mooren"'
Autor:
Pieter Simons, Erik Olofsen, Monique van Velzen, Maarten van Lemmen, René Mooren, Tom van Dasselaar, Patrick Mohr, Florian Hammes, Rutger van der Schrier, Marieke Niesters, Albert Dahan
Publikováno v:
Frontiers in Pain Research, Vol 3 (2022)
Ketamine is administered predominantly via the intravenous route for the various indications, including anesthesia, pain relief and treatment of depression. Here we report on the pharmacokinetics of sublingual and buccal fast-dissolving oral-thin-fil
Externí odkaz:
https://doaj.org/article/891d0d1bc2c948f0a6c320480e54f1c7
Autor:
Andreas Duma, Jojanneke van den Beukel, Liesbeth Siebers, René Mooren, Marieke Niesters, Leon Aarts, Thomas K. Henthorn, Kelly Jonkman, Erik Olofsen, Albert Dahan, Monique van Velzen
Publikováno v:
Anesthesiology, 127(4), 675-683
Background Esketamine is traditionally administered via intravenous or intramuscular routes. In this study we developed a pharmacokinetic model of inhalation of nebulized esketamine with special emphasis on pulmonary absorption and bioavailability. M
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f92a4f86d03a280833b03941095ad4
http://hdl.handle.net/1887/115650
http://hdl.handle.net/1887/115650
Autor:
Daniël Kleinloog, Joop M. A. van Gerven, Erica S. Klaassen, Jasper Stevens, René Mooren, Albert Dahan, Anna Uit den Boogaard, Jan Freijer
Publikováno v:
Journal of Psychopharmacology, 29(4), 401-413
The psychomimetic effects that occur after acute administration of ketamine can constitute a model of psychosis and antipsychotic drug action. However, the optimal dose/concentration has not been established and there is a large variety in outcome me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::899911924c2d6e5d8639e8a0d542a8c4
http://hdl.handle.net/1887/106612
http://hdl.handle.net/1887/106612
Autor:
Frank H. M. Engbers, Albert Dahan, Raymonda Romberg, Erik Olofsen, Hans Bijl, René Mooren, Benjamin Kest
Publikováno v:
Anesthesiology. 103:130-139
Background To assess whether patient sex contributes to the interindividual variability in alfentanil analgesic sensitivity, the authors compared male and female subjects for pain sensitivity after alfentanil using a pharmacokinetic-pharmacodynamic m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe455f9e14412bb4a18f99a488f46174
https://doi.org/10.1097/00000542-200507000-00020
https://doi.org/10.1097/00000542-200507000-00020
Autor:
Maarten Swartjes, Albert Dahan, Martin C.R. Bauer, Natasja Geleijnse, René Mooren, Ingeborg Noppers, Leon Aarts, Elise Sarton, Marieke Niesters
Publikováno v:
European Journal of Pain, 15(9), 942-949
To assess the analgesic efficacy of the N-methyl-D-aspartate receptor antagonist S(+)-ketamine on fibromyalgia pain, the authors performed a randomized double blind, active placebo-controlled trial. Twenty-four fibromyalgia patients were randomized t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c9e744e21d5604dc9d2c174c48429ee
https://hdl.handle.net/1887/110580
https://hdl.handle.net/1887/110580
Autor:
Ingeborg Noppers, René Mooren, Evan D. Kharasch, Leon Aarts, Elise Sarton, Marieke Niesters, Erik Olofsen, Albert Dahan
Publikováno v:
Anesthesiology
Anesthesiology, 114(6), 1435-1445
Anesthesiology, 114(6), 1435-1445
Background Low-dose ketamine is used as analgesic for acute and chronic pain. It is metabolized in the liver to norketamine via cytochrome P450 (CYP) enzymes. There are few human data on the involvement of CYP enzymes on the elimination of norketamin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ff10f02ea9c90ed42a5eaca850c4f40
https://hdl.handle.net/1887/109278
https://hdl.handle.net/1887/109278
Autor:
Albert Dahan, Jan den Hartigh, Leon Aarts, Elise Sarton, Eveline L. A. van Dorp, Terry Smith, Erik Olofsen, René Mooren
Publikováno v:
Anesthesia and Analgesia, 111(3), 626-632
BACKGROUND: In pharmacokinetic pharmacodynamic modeling studies, venous plasma samples are sometimes used to derive pharmacodynamic model parameters. In the current study the extent of arteriovenous concentration differences of morphine-6-glucuronide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef5966a1aa184e730dcf311994a6e3a2
http://hdl.handle.net/1887/110667
http://hdl.handle.net/1887/110667
Autor:
Ingeborg Noppers, Martin C.R. Bauer, Albert Dahan, Erik Olofsen, Elise Sarton, René Mooren, Marnix Sigtermans
Publikováno v:
European Journal of Pain, 14(3), 302-307
Aims: The aim of the study was to explore the analgesic effect of the N-methyl-D-aspartate receptor (NMDAR) antagonist ketamine in acute experimental versus chronic spontaneous pain in Complex Regional Pain Syndrome type 1 (CRPS-1) patients. Methods:
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8cb0c98811aa88c7ed7caeec9a91ce8
https://hdl.handle.net/1887/109352
https://hdl.handle.net/1887/109352
Autor:
Mischa J. G. Simon, Jack W. van Kleef, René Mooren, Marije Reekers, F. Boer, Albert Dahan, Jaap Vuyk
Publikováno v:
Anesthesia and Analgesia, 110(2), 466-472
BACKGROUND: Indocyanine green plasma disappearance rate (ICG-PDR) is used to evaluate hepatic function. Although hepatic failure is generally said to occur with an ICG-PDR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc6076803dab3b1b10935e55a5ca5ece
http://hdl.handle.net/1887/110403
http://hdl.handle.net/1887/110403
Publikováno v:
British Journal of Anaesthesia. 68:370-375
We have studied the pulmonary extraction and retention of sufentanil, alfentanil and morphine using a double indicator technique in 30 patients undergoing elective aortocoronary bypass surgery. Patients were allocated to three groups (10 each) to rec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f38e96da7d532d4118df8d5e6dd959b
https://doi.org/10.1093/bja/68.4.370
https://doi.org/10.1093/bja/68.4.370