Zobrazeno 1 - 6
of 6
pro vyhledávání: '"René Markgraf"'
Autor:
Peter Schlattmann, Thomas Lehmann, Tim Rahmel, Johannes Roth, Peter Kranke, Frank M Brunkhorst, Andreas Greinacher, Patrick Meybohm, Philipp Helmer, Stefan Hagel, Florian Rißner, Michael Bauer, Matthias Gründling, Sven-Olaf Kuhn, Christian Fuchs, Luis Ferreira Moita, Frank Bloos, Matthias Michael, Ulrike Schumacher, Matthias Unterberg, Daniel Thomas-Rüddel, Christiane Helbig, Johannes Ehler, Heiko Schenk, Thomas Köcher, Markus Gräler, Ann-Julika Heger, Sebastian Weis, Karen Dlubatz, Jakob Hammersen, Katja Leonhardt, René Markgraf, Franziska Röstel, Nicole Schwarze, Mariann Städtler, Wolfgang Vivas-Varela, Andre Hagedorn, Andrea Wittkowski, Florian Rumpf, Tobias Haas, Sebastian Hottenrott, Eva Kranke, Marianne Neuf, Anke Reppchen, Daniel Röder, Julius Schmidt
Publikováno v:
BMJ Open, Vol 14, Iss 4 (2024)
Introduction Sepsis remains the major cause of death among hospitalised patients in intensive care. While targeting sepsis-causing pathogens with source control or antimicrobials has had a dramatic impact on morbidity and mortality of sepsis patients
Externí odkaz:
https://doaj.org/article/61a05aa5bd5545d9812046f23ab53e28
Autor:
Enrico Leipold, Stefan H. Heinemann, René Markgraf, Oliver Hartley, Jana Schirmeyer, Marianne Paolini-Bertrand
Publikováno v:
British Journal of Pharmacology, Vol. 167, No 3 (2012) pp. 576-86
BACKGROUND AND PURPOSE Voltage-gated sodium channels (Na(V) channels) are key players in the generation and propagation of action potentials, and selective blockade of these channels is a promising strategy for clinically useful suppression of electr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::301aa490031217cb0f1423bded86ea00
https://doi.org/10.1111/j.1476-5381.2012.02004.x
https://doi.org/10.1111/j.1476-5381.2012.02004.x
Autor:
Philippe Favreau, Rolf Boelens, Jordi Molgó, Hubert François Gaertner, Daniel Bertrand, Jan Tytgat, Enrico Leipold, Henry G. Hocking, Ludovic Carlier, Dieter D' hoedt, Reto Stöcklin, Marco Cordova, Sébastien Schlumberger, René Markgraf, Oliver Hartley, Evelyne Benoit, Marianne Paolini-Bertrand, Stefan H. Heinemann
Publikováno v:
British Journal of Pharmacology. 166:1654-1668
BACKGROUND AND PURPOSE The µ-conopeptide family is defined by its ability to block voltage-gated sodium channels (VGSCs), a property that can be used for the development of myorelaxants and analgesics. We characterized the pharmacology of a new µ-c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a0ee1bff0a091ed2e3b18b5f7226b2f0
https://doi.org/10.1111/j.1476-5381.2012.01837.x
https://doi.org/10.1111/j.1476-5381.2012.01837.x
Autor:
Diana Imhof, Jana Schirmeyer, Alesia Miloslavina, Michael Kijas, René Markgraf, Stefan H. Heinemann, Enrico Leipold
Publikováno v:
Neuropharmacology. 61:105-111
Voltage-gated sodium channels (Na(V) channels) play a pivotal role in neuronal excitability; they are specifically targeted by μ-conotoxins from the venom of marine cone snails. These peptide toxins bind to the outer vestibule of the channel pore th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15bc7b9496c6f072d11aa2791d798aec
https://doi.org/10.1016/j.neuropharm.2011.03.008
https://doi.org/10.1016/j.neuropharm.2011.03.008
Autor:
Josef Priller, Serguei N. Skatchkov, Harald Prüss, Katharina N. Seidel, Stefan H. Heinemann, René Markgraf, Misty J. Eaton, Rüdiger W. Veh, Mikhail Salzmann, Markus Höltje, Heike Heilmann, Christian Derst
Publikováno v:
Glia. 59:893-902
Large-conductance Ca2+-activated (BK) potassium channels are centrally involved in neurovascular coupling, immunity, and neural transmission. The ability to be synergistically activated by membrane depolarization, different ligands and intracellular
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7343ebda386f285bdb0abacf0ccfe3d8
https://doi.org/10.1002/glia.21160
https://doi.org/10.1002/glia.21160
Autor:
Andreas Henke, Matthias Görlach, Holger H. Sigusch, Roland Zell, Michaela Schmidtke, Brigitte Glück, René Markgraf, Axel Stelzner
Publikováno v:
Medical Microbiology and Immunology. 193:91-100
The antiviral effect of nitric oxide (NO)-releasing compounds was investigated. Using bacterially expressed and purified proteinases 2A and 3C of coxsackievirus B3, in vitro assays demonstrated the inhibition of the 2A proteinase activity in the pres
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d3af979a6c854eb779a426ef033def2
https://doi.org/10.1007/s00430-003-0198-6
https://doi.org/10.1007/s00430-003-0198-6