Zobrazeno 1 - 10
of 628
pro vyhledávání: '"René Leemans"'
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss Suppl 2 (2021)
Externí odkaz:
https://doaj.org/article/96358219d45f48909e26fab2ae725a47
Autor:
Tara Muijlwijk, Irene H. Nauta, Anabel van der Lee, Kari J. T. Grünewald, Arjen Brink, Sonja H. Ganzevles, Robert J. Baatenburg de Jong, Lilit Atanesyan, Suvi Savola, Mark A. van de Wiel, Laura A. N. Peferoen, Elisabeth Bloemena, Rieneke van de Ven, C. René Leemans, Jos B. Poell, Ruud H. Brakenhoff
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-18 (2024)
Abstract Cancer is caused by an accumulation of somatic mutations and copy number alterations (CNAs). Besides mutations, these copy number changes are key characteristics of cancer development. Nonetheless, some tumors show hardly any CNAs, a remarka
Externí odkaz:
https://doaj.org/article/225436245a4a4f2badda609a77918405
Autor:
Bernard A Fox, Rieneke van de Ven, Carmen Ballesteros-Merino, Tara Muijlwijk, Sonja H Ganzevles, Ruud H Brakenhoff, Jos B Poell, Dennis N L M Nijenhuis, C René Leemans, Laura A N Peferoen, Elisabeth Bloemena, Fatima Ekhlas
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Approximately 50% of head and neck squamous cell carcinomas (HNSCC) recur after treatment with curative intent. Immune checkpoint inhibitors are treatment options for recurrent/metastatic HNSCC; however, less than 20% of patients respond.
Externí odkaz:
https://doaj.org/article/706241e19a784c6ebfc691493690aafb
Autor:
Tanja D de Gruijl, Rieneke van de Ven, K Hakki Karagozoglu, Pim de Graaf, Ronald Boellaard, Ruud H Brakenhoff, C René Leemans, Gerben J C Zwezerijnen, C Willemien Menke-van der Houven van Oordt, Iris H C Miedema, Niels E Wondergem, Jan-Jaap Hendrickx, Simone E J Eerenstein, Rolf J Bun, Dorien C Mulder, Jens Voortman, Albert D Windhorst, J Pascal Hagers, Laura A N Peferoen, Elisabeth Bloemena
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 7 (2024)
Background Addition of neoadjuvant immune checkpoint inhibition to standard-of-care interventions for locally advanced oral cancer could improve clinical outcome.Methods In this study, 16 evaluable patients with stage III/IV oral cancer were treated
Externí odkaz:
https://doaj.org/article/3a0f349d6bd74bb79ff5d9ffc2077cbb
Autor:
von Buchwald, Christian, Jakobsen, Kathrine Kronberg, Carlander, Amanda-Louise Fenger, Tous, Sara, Grønhøj, Christian, Rasmussen, Jacob H., Brooks, Jill, Taberna, Miren, Mena, Marisa, Morey, Francisca, Bruni, Laia, Batis, Nikolaos, Brakenhoff, Ruud H., René Leemans, C., Jong, Robert J.Baatenburg de, Klussmann, Jens Peter, Wuerdemann, Nora, Wagner, Steffen, Dalianis, Tina, Marklund, Linda o, Mirghani, Haïtham, Schache, Andrew, James, Jaqueline A., Huang, Shao Hui, O’Sullivan, Brian, Nankivell, Paul, Broglie, Martina A., Hoffmann, Markus, Quabius, Elgar Susanne, Anderson, Lesley A., Craig, Stephanie G., Alemany, Laia, Mehanna, Hisham
Publikováno v:
In European Journal of Cancer November 2024 211
Autor:
Jan B. Vermorken, Volker Budach, C. René Leemans, Jean-Pascal Machiels, Piero Nicolai, Brian O'Sullivan
This is an open access book.With a wealth of exciting data emerging in this rapidly evolving field this book will review the state-of-the-art knowledge with emphasis on multidisciplinary decision and management of head and neck cancer. The book provi
Autor:
Jan B. Vermorken, Volker Budach, C. René Leemans, Jean-Pascal Machiels, Piero Nicolai, Brian O’Sullivan
This open access book discusses the most current issues in head and neck cancer with a focus on current trends such as biomarkers, precision medicine and immunotherapy. New approaches in the diagnosis such as liquid biopsies and imaging biomarkers to
Autor:
Anna Corti, Loris De Cecco, Stefano Cavalieri, Deborah Lenoci, Federico Pistore, Giuseppina Calareso, Davide Mattavelli, Pim de Graaf, C. René Leemans, Ruud H. Brakenhoff, Marco Ravanelli, Tito Poli, Lisa Licitra, Valentina Corino, Luca Mainardi
Publikováno v:
Biomarker Research, Vol 11, Iss 1, Pp 1-14 (2023)
Abstract Background . At present, the prognostic prediction in advanced oral cavity squamous cell carcinoma (OCSCC) is based on the tumor-node-metastasis (TNM) staging system, and the most used imaging modality in these patients is magnetic resonance
Externí odkaz:
https://doaj.org/article/70e9ed0a5e974d13933a26dc8dbdbbf4
Autor:
Bernard A Fox, Rieneke van de Ven, Yoshinobu Koguchi, Venkatesh Rajamanickam, Tara Muijlwijk, Sonja H Ganzevles, Ruud H Brakenhoff, Arjen Brink, Changlin Ke, Joseph N Fass, Jos B Poell, Dennis N L M Nijenhuis, C René Leemans
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 12, Iss 1 (2024)
Background The response rate to immune checkpoint inhibitors targeting programmed cell death 1 (PD-1) receptor is 13%–18% for patients with recurrent or metastatic head and neck squamous cell carcinoma (HNSCC). Detailed understanding of the tumor i
Externí odkaz:
https://doaj.org/article/4c0703b158e44abebdb94f559e449d18
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
ObjectiveHead and neck cancer care is highly complex, and multidisciplinary team meetings (MDTs) are vital for improved outcomes. In the Netherlands, head and neck cancer care is practiced in eight high-volume head and neck oncologic centers (HNOC) a
Externí odkaz:
https://doaj.org/article/8d9d78c2e278435188d1d1f5d864e41d