Zobrazeno 1 - 10
of 60
pro vyhledávání: '"René Deenen"'
Autor:
Marianne Wammers, Anna-Kathrin Schupp, Johannes G. Bode, Christian Ehlting, Stephanie Wolf, René Deenen, Karl Köhrer, Dieter Häussinger, Dirk Graf
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-1 (2022)
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
Externí odkaz:
https://doaj.org/article/743e0835b3d2435d8ad490e274e98ad2
Autor:
Kensuke Shima, Inga Kaufhold, Thomas Eder, Nadja Käding, Nis Schmidt, Iretiolu M. Ogunsulire, René Deenen, Karl Köhrer, Dirk Friedrich, Sophie E. Isay, Florian Grebien, Matthias Klinger, Barbara C. Richer, Ulrich L. Günther, George S. Deepe, Thomas Rattei, Jan Rupp
Publikováno v:
mBio, Vol 12, Iss 2 (2021)
ABSTRACT Infection with the obligate intracellular bacterium Chlamydia trachomatis is the most common bacterial sexually transmitted disease worldwide. Since no vaccine is available to date, antimicrobial therapy is the only alternative in C. trachom
Externí odkaz:
https://doaj.org/article/1f21d46625f04f0eb17183c2f20ab571
Autor:
Niloofar Ale-Agha, Christine Goy, Philipp Jakobs, Ioakim Spyridopoulos, Stefanie Gonnissen, Nadine Dyballa-Rukes, Karin Aufenvenne, Florian von Ameln, Mark Zurek, Tim Spannbrucker, Olaf Eckermann, Sascha Jakob, Simone Gorressen, Marcel Abrams, Maria Grandoch, Jens W Fischer, Karl Köhrer, René Deenen, Klaus Unfried, Joachim Altschmied, Judith Haendeler
Publikováno v:
PLoS Biology, Vol 16, Iss 6, p e2004408 (2018)
We show that the cyclin-dependent kinase inhibitor 1B (CDKN1B)/p27, previously known as a cell cycle inhibitor, is also localized within mitochondria. The migratory capacity of endothelial cells, which need intact mitochondria, is completely dependen
Externí odkaz:
https://doaj.org/article/b537d1dd586d462a80e9c8203d121f2e
Publikováno v:
PLoS ONE, Vol 12, Iss 7, p e0181383 (2017)
Mycoplasma hominis is the second smallest facultative pathogen of the human urogenital tract. With less than 600 protein-encoding genes, it represents an ideal model organism for the study of host-pathogen interactions. For a comprehensive characteri
Externí odkaz:
https://doaj.org/article/631ac91a4b14447fa4eccb4b6dd6c815
Autor:
Jan Korte, Marina Alber, Carolina M Trujillo, Karl Syson, Hendrik Koliwer-Brandl, René Deenen, Karl Köhrer, Michael A DeJesus, Travis Hartman, William R Jacobs, Stephen Bornemann, Thomas R Ioerger, Sabine Ehrt, Rainer Kalscheuer
Publikováno v:
PLoS Pathogens, Vol 12, Iss 12, p e1006043 (2016)
Trehalose biosynthesis is considered an attractive target for the development of antimicrobials against fungal, helminthic and bacterial pathogens including Mycobacterium tuberculosis. The most common biosynthetic route involves trehalose-6-phosphate
Externí odkaz:
https://doaj.org/article/956cafd630f5476e943eda980fef8156
Autor:
Birgit Henrich, Ilka Hermann, Mara Di Giulio, Karl Köhrer, René Deenen, Sugi Sivalingam, Ulrike Peters, Thomas Beikler, Ralf Janda, Stefan Rüttermann
Publikováno v:
Advances in Materials Science and Engineering, Vol 2016 (2016)
Purpose. To introduce additional methods to detect and to quantify single pathogens in the complex biofilm formation on an antibacterial dental material. Materials and Methods. A conventional (ST) and an antibacterial dental composite (B) were manufa
Externí odkaz:
https://doaj.org/article/8ca3844512124b1fb829dee8296ca610
Autor:
Fabian Wolpert, Caroline Happold, Guido Reifenberger, Ana-Maria Florea, René Deenen, Patrick Roth, Marian Christoph Neidert, Katrin Lamszus, Manfred Westphal, Michael Weller, Günter Eisele
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0139603 (2015)
Immunotherapy targeting glioblastoma initiating cells (GIC) is considered a promising strategy. However, GIC are prone to evade immune response and there is a need for potent adjuvants. IFN-β might enhance the immune response and here we define its
Externí odkaz:
https://doaj.org/article/53e824d657814141a7cb2206d37e9ad3
Autor:
Anna C Luca, Sabrina Mersch, René Deenen, Stephan Schmidt, Isabelle Messner, Karl-Ludwig Schäfer, Stephan E Baldus, Wolfgang Huckenbeck, Roland P Piekorz, Wolfram T Knoefel, Andreas Krieg, Nikolas H Stoecklein
Publikováno v:
PLoS ONE, Vol 8, Iss 3, p e59689 (2013)
Three-dimensional (3D) tumor cell cultures grown in laminin-rich-extracellular matrix (lrECM) are considered to reflect human tumors more realistic as compared to cells grown as monolayer on plastic. Here, we systematically investigated the impact of
Externí odkaz:
https://doaj.org/article/fd5fe69b257a456cb73ee98f60d9ee35
Autor:
Julia Bosch, Amelie Pia Houben, Tatiana Hennicke, René Deenen, Karl Köhrer, Stefanie Liedtke, Gesine Kögler
Publikováno v:
Stem Cells International, Vol 2013 (2013)
With regard to the bone-regenerative capacity, bone marrow stromal cells (BMSC) can still be termed the “gold standard.” Nevertheless, neonatal stromal cells from cord blood (CB) feature advantages concerning availability, immaturity, and prolife
Externí odkaz:
https://doaj.org/article/32b502c8da094ed599a517668bd8e51b
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e54219 (2013)
Mycoplasma hominis is a facultative human pathogen primarily associated with bacterial vaginosis and pelvic inflammatory disease, but it is also able to spread to other sites, leading to arthritis or, in neonates, meningitis. With a minimal set of 53
Externí odkaz:
https://doaj.org/article/82fc5e3f3b0a4699a88beebed7256ade