Zobrazeno 1 - 10
of 91
pro vyhledávání: '"René C.-Gaudreault"'
Autor:
Antoine Carpentier, Luis Misal, Sharwatie Ramsaywack, Christopher M. Vogels, Stéphane Gobeil, Stephen A. Westcott, René C.-Gaudreault, Frédéric-Georges Fontaine
Publikováno v:
Results in Chemistry, Vol 7, Iss , Pp 101493- (2024)
Boron-containing and boron-omited derivatives based on the structural motif of capsaicin have been synthesized. The vanillyl amide moiety of the parent capsaicin molecule was retained and the boron atom was incorporated into the aliphatic region. All
Externí odkaz:
https://doaj.org/article/01a00f627f254965b08bd69d6525fc47
Autor:
Charu Kothari, Alisson Clemenceau, Geneviève Ouellette, Kaoutar Ennour-Idrissi, Annick Michaud, René C.-Gaudreault, Caroline Diorio, Francine Durocher
Publikováno v:
Cancers, Vol 13, Iss 14, p 3557 (2021)
Triple-negative breast cancer (TNBC) is a major concern among the different subtypes of breast cancer (BC) due to the lack of effective treatment. In a previous study by our group aimed at understanding the difference between TNBC and non-TNBC tumors
Externí odkaz:
https://doaj.org/article/015a9820f5fd4d8c856c6d6020c65eed
Autor:
Jessica S Fortin, Alexandre Patenaude, Rena G Deschesnes, Marie-France Côté, Eric Petitclerc, René C.-Gaudreault
Publikováno v:
Journal of Pharmacy & Pharmaceutical Sciences, Vol 13, Iss 2 (2010)
PURPOSE. We investigated the involvement of MAPK signaling in the cell death mechanisms of classical microtubule interfering agents (MIA) and aryl-3-(2-chloroethyl)ureas (CEU) acting as antimitotics, along with CEU that don’t affect directly microt
Externí odkaz:
https://doaj.org/article/53a1881ce0b84ba29a05b27c0efbe9e2
Autor:
Atziri Corin Chavez Alvarez, Chahrazed Bouzriba, Emmanuel Moreau, Philippe Auzeloux, Sophie Besse, Vincent Ouellette, Mitra Zarifi Khosroshahi, Marie-France Côté, Sylvie Pilote, Elisabeth Miot-Noirault, Jean-Michel Chezal, Chantale Simard, René C -Gaudreault, Sébastien Fortin
Publikováno v:
Journal of Medicinal Chemistry. 66:2477-2497
Autor:
René C.-Gaudreault, Marie-France Côté, Jacques Lacroix, Éric Petitclerc, Jean L.C. Rousseau, Réna G. Deschesnes, Alexandre Patenaude
Supplementary Figure 3 from New Soft Alkylating Agents with Enhanced Cytotoxicity against Cancer Cells Resistant to Chemotherapeutics and Hypoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fbe591730b8b2441ad72c114d464028
https://doi.org/10.1158/0008-5472.22370597
https://doi.org/10.1158/0008-5472.22370597
Autor:
René C.-Gaudreault, Marie-France Côté, Jacques Lacroix, Éric Petitclerc, Jean L.C. Rousseau, Réna G. Deschesnes, Alexandre Patenaude
Chloroethylureas (CEU) are soft alkylating agents that covalently bind to β-tubulin (βTAC) and affect microtubule polymerization dynamics. Herein, we report the identification of a CEU subset and its corresponding oxazolines, which induce cell grow
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712ac88f4e645fec73ddb078788e182a
https://doi.org/10.1158/0008-5472.c.6496454
https://doi.org/10.1158/0008-5472.c.6496454
Autor:
René C.-Gaudreault, Marie-France Côté, Jacques Lacroix, Éric Petitclerc, Jean L.C. Rousseau, Réna G. Deschesnes, Alexandre Patenaude
Supplementary Figure 2 from New Soft Alkylating Agents with Enhanced Cytotoxicity against Cancer Cells Resistant to Chemotherapeutics and Hypoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::414fcc3f61b66dc729c6505b5d14030e
https://doi.org/10.1158/0008-5472.22370603.v1
https://doi.org/10.1158/0008-5472.22370603.v1
Autor:
René C.-Gaudreault, Marie-France Côté, Jacques Lacroix, Éric Petitclerc, Jean L.C. Rousseau, Réna G. Deschesnes, Alexandre Patenaude
Supplementary Figure 1 from New Soft Alkylating Agents with Enhanced Cytotoxicity against Cancer Cells Resistant to Chemotherapeutics and Hypoxia
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac292b03d61b7d2be359707c2792261f
https://doi.org/10.1158/0008-5472.22370606.v1
https://doi.org/10.1158/0008-5472.22370606.v1
Autor:
Martin Perreault, Sébastien Tremblay, Stéphane Gobeil, René C.-Gaudreault, Marie-France Côté, Joël Boutin
Publikováno v:
Medicinal Chemistry Research. 29:1424-1437
Inflammation is an important, normal, and complex host defense response to injury, autoimmune responses or infectious agents. However, chronic inflammation is associated with diseases like rheumatoid arthritis, cancers, cardiovascular diseases, diabe
Autor:
Vincent Ouellette, René C.-Gaudreault, Gervais Bérubé, Marie-France Côté, Heidar-Ali Tajmir-Riahi
Publikováno v:
European Journal of Medicinal Chemistry. 179:660-666
Prostate cancer is the most diagnosed type of cancer in men in Canada. One out of eight men will be stricken with this disease during the course of his life. It is noteworthy that, at initial diagnoses 80–90% of cancers are androgen dependent. Henc