Zobrazeno 1 - 10
of 14
pro vyhledávání: '"René A.W. van Lier"'
Autor:
Michiel C. van Aalderen, Maartje van den Biggelaar, Ester B.M. Remmerswaal, Floris P.J. van Alphen, Alexander B. Meijer, Ineke J.M. ten Berge, René A.W. van Lier
Publikováno v:
Cell Reports, Vol 19, Iss 5, Pp 1068-1079 (2017)
Summary: Pathogens trigger T cells to express distinct sets of effector proteins. To better understand the molecular mechanisms that drive functional specification, we used high-resolution mass spectrometry and label-free protein quantification to me
Externí odkaz:
https://doaj.org/article/98eef1ee188d4fcb8f35110efad6283b
Autor:
Carlos van der Putten, Ester B.M. Remmerswaal, Matty L. Terpstra, Nelly D. van der Bom, Jesper Kers, Ineke J.M. ten Berge, Suzanne E. Geerlings, René A.W. van Lier, Frederike J. Bemelman, Michiel C. van Aalderen
Publikováno v:
Cells, Vol 10, Iss 2, p 288 (2021)
Background: At border sites, and in internal organs, tissue resident memory T cells (TRM) contribute to the immune barrier against pathogens like viruses, bacteria, fungi, and cancer. However, information on the presence and function of these cells i
Externí odkaz:
https://doaj.org/article/bd07b9dcfb0540859617e33e9a2a4c91
Autor:
Gin-Wen Chang, Cheng-Chih Hsiao, Yen-Ming Peng, Felipe A. Vieira Braga, Natasja A.M. Kragten, Ester B.M. Remmerswaal, Martijn D.B. van de Garde, Rachel Straussberg, Gabriele M. König, Evi Kostenis, Vera Knäuper, Linde Meyaard, René A.W. van Lier, Klaas P.J.M. van Gisbergen, Hsi-Hsien Lin, Jörg Hamann
Publikováno v:
Cell Reports, Vol 15, Iss 8, Pp 1757-1770 (2016)
Natural killer (NK) cells possess potent cytotoxic mechanisms that need to be tightly controlled. Here, we explored the regulation and function of GPR56/ADGRG1, an adhesion G protein-coupled receptor implicated in developmental processes and expresse
Externí odkaz:
https://doaj.org/article/5fb9b1597dee429ea865037cd9e6f62f
Autor:
Taco W. Kuijpers, Ester M.M. van Leeuwen, Barbara H. Barendregt, Paul Klarenbeek, Daan J. aan de Kerk, Paul A. Baars, Machiel H. Jansen, Niek de Vries, René A.W. van Lier, Mirjam van der Burg
Publikováno v:
Haematologica, Vol 98, Iss 7 (2013)
Mutations in the common gamma chain (γc, CD132, encoded by the IL2RG gene) can lead to B+T−NK− X-linked severe combined immunodeficiency, as a consequence of unresponsiveness to γc-cytokines such as interleukins-2, -7 and -15. Hypomorphic mutat
Externí odkaz:
https://doaj.org/article/3135c2c8e5d44233ad97b1a493673ae6
Autor:
René A.W. van Lier, Pleun Hombrink
Publikováno v:
Journal of Experimental Medicine. 219
Tissue-resident memory T cells (TRM cells) reside in the epithelium and contribute to the first line defense against invading pathogens. Snyder et al. (2022. J. Exp. Med.https://doi.org/10.1084/jem.20212059) now report that clonally expanded, recipie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c766ce1fc1756367180f09213faba818
https://doi.org/10.1084/jem.20220121
https://doi.org/10.1084/jem.20220121
Autor:
Anna E. Oja, Florencia Morgana, Ruth Hagen, Cherien A. Ghandour, Martijn A. Nolte, Suzan H.M. Rooijakkers, René A.W. van Lier, Bart W. Bardoel, Pleun Hombrink
Local T cell responses are required for optimal protection of the lungs against airborne pathogens. This localized protection is mediated by various immune cells, including resident memory T cells (TRM). While human lung CD8+ TRM line the epithelium
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b501ec74f4f1c3f62799b56b7d4b8d68
https://doi.org/10.1101/2022.02.16.479923
https://doi.org/10.1101/2022.02.16.479923
Autor:
René A.W. van Lier, Anno Saris, Ed Slot, Federica Linty, Theo Rispens, Boris M. Hogema, Ellen van der Schoot, Susan Cuvalay, Natasja A. M. Kragten, Anna E. Oja, Esther J. Nossent, Cherien A. Ghandour, Hans Vrielink, Leo M. A. Heunks, Gestur Vidarsson, Pleun Hombrink, Anja ten Brinke, Francis Swaneveld
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e28707e12a0d06386a79dab878b2bd30
https://doi.org/10.1002/eji.202048908/v2/response1
https://doi.org/10.1002/eji.202048908/v2/response1
Autor:
Věra M. J. Novotný, Ed Slot, Michel Molier, Jan H. M. Karregat, Johan Reimerink, Chantal B.E.M. Reusken, René A.W. van Lier, Johan IJlst, Boris M. Hogema, Hans L. Zaaijer
The world is combating an ongoing COVID-19 pandemic1-4. Health-care systems, society and the economy are impacted in an unprecedented way. It is unclear how many people have contracted the causative coronavirus (SARS-CoV-2) unknowingly. Therefore, re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46028aa6552b366252d18cb71169467b
https://doi.org/10.21203/rs.3.rs-25862/v1
https://doi.org/10.21203/rs.3.rs-25862/v1
Autor:
Astrid A. Bovens, Felix M. Behr, Natasja A. M. Kragten, Thomas H. Wesselink, Regina Stark, Klaas P.J.M. Gisbergen, René A.W. van Lier
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1327cebfe4b1e0bbade141772d1a13f7
https://doi.org/10.1002/eji.201948509/v2/response1
https://doi.org/10.1002/eji.201948509/v2/response1
Autor:
Ineke J. M. ten Berge, Mirjam H.M. Heemskerk, René A.W. van Lier, Ester M. M. van Leeuwen, Ester B. M. Remmerswaal
Publikováno v:
Blood, 108(9), 3121-3127. American Society of Hematology
To obtain insight into human CD4+ T cell differentiation and selection in vivo, we longitudinally studied cytomegalovirus (CMV)–specific CD4+ T cells after primary infection. Early in infection, CMV-specific CD4+ T cells have the appearance of inte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::655215cab9b396b389231d48eaf7b054
https://pure.amc.nl/en/publications/strong-selection-of-virusspecific-cytotoxic-cd4-tcell-clones-during-primary-human-cytomegalovirus-infection(b7b13b43-0b6b-4847-aca0-70eeaa8fd054).html
https://pure.amc.nl/en/publications/strong-selection-of-virusspecific-cytotoxic-cd4-tcell-clones-during-primary-human-cytomegalovirus-infection(b7b13b43-0b6b-4847-aca0-70eeaa8fd054).html