Zobrazeno 1 - 10
of 110
pro vyhledávání: '"René, Rezsohazy"'
Autor:
Estelle Renaux, Charlotte Baudouin, Olivier Schakman, Ondine Gay, Manon Martin, Damien Marchese, Younès Achouri, René Rezsohazy, Françoise Gofflot, Frédéric Clotman
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Motor activity is organized by neuronal networks composed of motor neurons and a wide variety of pre-motor interneuron populations located in the brainstem and spinal cord. Differential expression and single-cell RNA sequencing studies recently unvei
Externí odkaz:
https://doaj.org/article/4df343ff15cd4de595e1c6ea2dfabe69
Autor:
Gaëlle Odelin, Adèle Faucherre, Damien Marchese, Amélie Pinard, Hager Jaouadi, Solena Le Scouarnec, FranceGenRef Consortium, Raphaël Chiarelli, Younes Achouri, Emilie Faure, Marine Herbane, Alexis Théron, Jean-François Avierinos, Chris Jopling, Gwenaëlle Collod-Béroud, René Rezsohazy, Stéphane Zaffran
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-17 (2023)
Bicuspid aortic valve (BAV) is the most common cardiac defect and although highly heritable, few causal mutations have been identified. Here, the authors identify variants in the poly-histidine repeat motif of HOXA1 and show that its disruption leads
Externí odkaz:
https://doaj.org/article/f7e23b8b54634e9f9ca2535ee58a075d
Autor:
Magali Belpaire, Bruno Ewbank, Arnaud Taminiau, Laure Bridoux, Noémie Deneyer, Damien Marchese, Gipsi Lima-Mendez, Jean-François Baurain, Dirk Geerts, René Rezsohazy
Publikováno v:
Frontiers in Oncology, Vol 11 (2021)
Breast cancer is a heterogeneous disease and the leading cause of female cancer mortality worldwide. About 70% of breast cancers express ERα. HOX proteins are master regulators of embryo development which have emerged as being important players in o
Externí odkaz:
https://doaj.org/article/a4686644493249dc876740ee2e407464
Publikováno v:
Journal of Developmental Biology, Vol 9, Iss 4, p 56 (2021)
While the functions of HOX genes have been and remain extensively studied in distinct model organisms from flies to mice, the molecular biology of HOX proteins remains poorly documented. In particular, the mechanisms involved in regulating the activi
Externí odkaz:
https://doaj.org/article/5f5d5f80f4b8483d8fe0f0d9a5a05b89
Autor:
Caroline Sauvegarde, Delphine Paul, Laure Bridoux, Alice Jouneau, Séverine Degrelle, Isabelle Hue, René Rezsohazy, Isabelle Donnay
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0165898 (2016)
We previously showed that the homeodomain transcription factor HOXB9 is expressed in mammalian oocytes and early embryos. However, a systematic and exhaustive study of the localization of the HOXB9 protein, and HOX proteins in general, during mammali
Externí odkaz:
https://doaj.org/article/098bf998cce54de9ad7f6f3938305328
Publikováno v:
PLoS ONE, Vol 10, Iss 10, p e0141347 (2015)
The homeodomain transcription factor Hoxa2 interacts with the RING-finger type E3 ubiquitin ligase RCHY1 and induces its proteasomal degradation. In this work, we dissected this non-transcriptional activity of Hoxa2 at the molecular level. The Hoxa2-
Externí odkaz:
https://doaj.org/article/f10c9ed923cc47a0a46e1aa33dc3053f
Publikováno v:
Belpaire, M, Taminiau, A, Geerts, D & Rezsohazy, R 2022, ' HOXA1, a breast cancer oncogene ', Biochimica et Biophysica Acta. Reviews on Cancer, vol. 1877, no. 4, 188747, pp. 188747 . https://doi.org/10.1016/j.bbcan.2022.188747
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer, Vol. 1877, no.4, p. 188747 (2022)
Biochimica et Biophysica Acta (BBA)-Reviews on Cancer, Vol. 1877, no.4, p. 188747 (2022)
More than 25 years ago, the first literature records mentioned HOXA1 expression in human breast cancer. A few years later, HOXA1 was confirmed as a proper oncogene in mammary tissue. In the following two decades, molecular data about the mode of acti
Autor:
René Rezsohazy, Jérôme Mallefet, Tomohiro Sugihara, Jérôme Delroisse, Mitsumasa Koyanagi, Akihisa Terakita, Laurent Duchatelet
Publikováno v:
Scientific Reports
Scientific Reports, Vol. 10, no.1, p. 10195 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
Scientific Reports, Vol. 10, no.1, p. 10195 (2020)
Scientific Reports, Vol 10, Iss 1, Pp 1-15 (2020)
The velvet belly lanternshark, Etmopterus spinax, uses counterillumination to disappear in the surrounding blue light of its marine environment. This shark displays hormonally controlled bioluminescence in which melatonin (MT) and prolactin (PRL) tri
Autor:
Bruno Hudry, Sophie Remacle, Marie-Claire Delfini, René Rezsohazy, Yacine Graba, Samir Merabet
Publikováno v:
PLoS Biology, Vol 10, Iss 6, p e1001351 (2012)
Hox transcription factors control a number of developmental processes with the help of the PBC class proteins. In vitro analyses have established that the formation of Hox/PBC complexes relies on a short conserved Hox protein motif called the hexapep
Externí odkaz:
https://doaj.org/article/176b748390114b9f84d890d5cc0e9ffa
Autor:
René Rezsohazy, Magali Belpaire, Hervé Degand, Pierre Morsomme, Laure Bridoux, Tamara Pringels, Amandine Draime
Publikováno v:
FEBS Letters. 592:1185-1201
HOXA1 belongs to the HOX family of transcription factors which are key regulators of animal development. Little is known about the molecular pathways controlling HOXA1. Recent data from our group revealed distinct partner proteins interacting with HO