Zobrazeno 1 - 10
of 42
pro vyhledávání: '"René, Hennig"'
Publikováno v:
Engineering, Vol 26, Iss , Pp 132-150 (2023)
As the roles of glycans in health and disease continue to be unraveled, it is becoming apparent that glycans’ immense complexity cannot be ignored. To fully delineate glycan structures, we developed an integrative approach combining a set of cost-e
Externí odkaz:
https://doaj.org/article/79d6f955893c4879851bc7d1e77f8b07
Autor:
Léa Chuzel, Samantha L. Fossa, Madison L. Boisvert, Samanta Cajic, René Hennig, Mehul B. Ganatra, Udo Reichl, Erdmann Rapp, Christopher H. Taron
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-17 (2021)
Abstract Background Sulfate modification of N-glycans is important for several biological functions such as clearance of pituitary hormones or immunoregulation. Yet, the prevalence of this N-glycan modification and its functions remain largely unexpl
Externí odkaz:
https://doaj.org/article/23378c5ccb8e488faa63d8ccb97cde6c
Publikováno v:
Molecules, Vol 28, Iss 4, p 1843 (2023)
Glycosylation, especially N-glycosylation, is one of the most common protein modifications, with immense importance at the molecular, cellular, and organismal level. Thus, accurate and reliable N-glycan analysis is essential in many areas of pharmace
Externí odkaz:
https://doaj.org/article/169405da7ed742ab9baa17f7c29db810
Autor:
Christina Fotopoulou, Thomas Berg, Annekristin Hausen, René Hennig, Rajiv Jalan, Massimo Malagó, Jeroen Capel, Andrea De Gottardi, Guido Stirnimann
Publikováno v:
BMC Palliative Care, Vol 18, Iss 1, Pp 1-9 (2019)
Abstract Background Malignant Ascites (MA) is a therapeutic dilemma significantly impairing patients’ quality of life (QoL). The Sequana Medical alfapump System (AP), a subcutaneous, externally rechargeable, implantable device, continually draining
Externí odkaz:
https://doaj.org/article/0310453e305e47819e3114a348acb574
Autor:
Anja Schaffert, Maja Hanić, Mislav Novokmet, Olga Zaytseva, Jasminka Krištić, Anja Lux, Lars Nitschke, Matthias Peipp, Marija Pezer, René Hennig, Erdmann Rapp, Gordan Lauc, Falk Nimmerjahn
Publikováno v:
Frontiers in Immunology, Vol 10 (2020)
Select residues in the biantennary sugar moiety attached to the fragment crystallizable of immunoglobulin G (IgG) antibodies can modulate IgG effector functions. Thus, afucosylated IgG glycovariants have enhanced cytotoxic activity, whereas IgG glyco
Externí odkaz:
https://doaj.org/article/1d611dbd27574706bdc1efeaf803f067
Autor:
Stefan Fritz, Katharina Feilhauer, André Schaudt, Hansjörg Killguss, Eduard Esianu, René Hennig, Jörg Köninger
Publikováno v:
BMC Surgery, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Pylorotomy and pyloroplasty in thoracoabdominal esophagectomy are routinely performed in many high-volume centers to prevent delayed gastric emptying (DGE) due to truncal vagotomy. Currently, controversy remains regarding the need
Externí odkaz:
https://doaj.org/article/9571f394b04d48feaa26d3398062c9f9
Autor:
Uwe Möginger, Sonja Grunewald, René Hennig, Chu-Wei Kuo, Falko Schirmeister, Harald Voth, Erdmann Rapp, Kay-Hooi Khoo, Peter H. Seeberger, Jan C. Simon, Daniel Kolarich
Publikováno v:
Frontiers in Oncology, Vol 8 (2018)
The glycome of one of the largest and most exposed human organs, the skin, as well as glycan changes associated with non-melanoma skin cancers have not been studied in detail to date. Skin cancers such as basal cell carcinoma (BCC) and squamous cell
Externí odkaz:
https://doaj.org/article/861d7b34bf424f7ca4632517589bbdaf
Autor:
Mehul B. Ganatra, Erdmann Rapp, Samantha L. Fossa, Udo Reichl, Samanta Cajic, Christopher H. Taron, Léa Chuzel, René Hennig, Madison L. Boisvert
Publikováno v:
Microbial Cell Factories, Vol 20, Iss 1, Pp 1-17 (2021)
Microbial Cell Factories
Microbial Cell Factories
BackgroundSulfate modification ofN-glycans is important for several biological functions such as clearance of pituitary hormones or immunoregulation. Yet, the prevalence of thisN-glycan modification and its functions remain largely unexplored. Charac
Publikováno v:
Experientia supplementum (2012). 112
The in-depth characterization of protein glycosylation has become indispensable in many research fields and in the biopharmaceutical industry. Especially knowledge about modulations in immunoglobulin G (IgG) N-glycosylation and their effect on immuni
Autor:
René Hennig, Timo Kehl, Seema Noor, Xian-Zhong Ding, Sambasiva M. Rao, Frank Bergmann, Gerhard Fürstenberger, Markus W. Büchler, Helmut Friess, Peter Krieg, Thomas E. Adrian
Publikováno v:
Neoplasia: An International Journal for Oncology Research, Vol 9, Iss 11, Pp 917-926 (2007)
Pancreatic cancer patients have an abysmal prognosis because of late diagnosis and lack of therapeutic options. Pancreatic intraepithelial neoplasias (PaniNs), the precursor lesions, are a potential target for chemoprevention. Targeting eicosanoid pa
Externí odkaz:
https://doaj.org/article/9c16cb6c7c9d45d2ad4270d0813265b2