Zobrazeno 1 - 10
of 339
pro vyhledávání: '"René, Hen"'
Autor:
Antoine Besnard, Tomer Langberg, Sally Levinson, Duong Chu, Cinzia Vicidomini, Kimberly N. Scobie, Andrew J. Dwork, Victoria Arango, Gorazd B. Rosoklija, J. John Mann, René Hen, E. David Leonardo, Maura Boldrini, Amar Sahay
Publikováno v:
Cell Reports, Vol 23, Iss 11, Pp 3183-3196 (2018)
Summary: Stress exposure is associated with the pathogenesis of psychiatric disorders, including post-traumatic stress disorder (PTSD) and major depressive disorder (MDD). Here, we show in rodents that chronic stress exposure rapidly and transiently
Externí odkaz:
https://doaj.org/article/3c57edd6b6b14a11979a871628b1efed
Autor:
Frank Yocca, Carlos M. Villalon, Andrew Sleight, Trevor Sharp, Pramod R. Saxena, Bryan Roth, John A. Peters, Stephen J. Peroutka, John Neumaier, Ewan Mylecharane, Derek N. Middlemiss, Graeme R. Martin, Luc Maroteaux, Klaus Peter Latté, Patrick P. A. Humphrey, Daniel Hoyer, Rebecca Hills, Katharine Herrick-Davis, Julie Hensler, René Hen, Paul R. Hartig, Michel Hamon, Mark Hamblin, Manfred Göthert, Richard M. Eglen, Aline Dumuis, Marlene L. Cohen, Amy Butler, Theresa Branchek, Joel Bockaert, Gordon Baxter, Nicholas M. Barnes, Rodrigo Andrade
Publikováno v:
IUPHAR/BPS Guide to Pharmacology CITE. 2023
5-HT receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on 5-HT receptors [198] and subsequently revised [180]) are, with the exception of the ionotropic 5-HT3 class, GPCRs where the endogenous agonist is 5-hydroxytryptamine. The diversi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4af4d3d745f0e8e57bd57986ad25334a
https://doi.org/10.2218/gtopdb/f1/2023.1
https://doi.org/10.2218/gtopdb/f1/2023.1
Autor:
Barbara Planchez, Natalia Lagunas, Anne-Marie Le Guisquet, Marc Legrand, Alexandre Surget, René Hen, Catherine Belzung
Publikováno v:
Cells, Vol 10, Iss 5, p 972 (2021)
Many studies evaluated the functional role of adult hippocampal neurogenesis (AHN) and its key role in cognitive functions and mood regulation. The effects of promoting AHN on the recovery of stress-induced symptoms have been well studied, but its in
Externí odkaz:
https://doaj.org/article/fdeb4cfd7e6e4537931cb96ed17b629b
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::12023884ab430ce30cba477f48358093
https://doi.org/10.3791/64863
https://doi.org/10.3791/64863
Autor:
Katherine M. Nautiyal, René Hen
Publikováno v:
F1000Research, Vol 6 (2017)
The role of serotonin in major depressive disorder (MDD) is the focus of accumulating clinical and preclinical research. The results of these studies reflect the complexity of serotonin signaling through many receptors, in a large number of brain reg
Externí odkaz:
https://doaj.org/article/afe733ffdbb74be7b673966ea76c638f
Autor:
Karly Tegang, Amit Etkin, Kerry Ressler, Jakob Hartmann, Clara Stucke, Adam Savitz, Wei Wu, Maria Ferreira da Silva, René Hen, Wei-li Chang
Publikováno v:
Biological Psychiatry. 93:S226
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::817c71657f9611a0acac62bcfe1cbd91
https://doi.org/10.1016/j.biopsych.2023.02.567
https://doi.org/10.1016/j.biopsych.2023.02.567
Autor:
Aaron S Coyner, Renee C Ryals, Cristy A Ku, Cody M Fischer, Rachel C Patel, Shreya Datta, Paul Yang, Yuquan Wen, René Hen, Mark E Pennesi
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159776 (2016)
To assess the neuroprotective effects of flibanserin (formerly BIMT-17), a dual 5-HT1A agonist and 5-HT2A antagonist, in a light-induced retinopathy model.Albino BALB/c mice were injected intraperitoneally with either vehicle or increasing doses of f
Externí odkaz:
https://doaj.org/article/58b04a535e554b66a5804b6129cfa245
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-11 (2020)
Nature Communications
Nature communications, vol 11, iss 1
Nature Communications
Nature communications, vol 11, iss 1
Ventral hippocampal CA1 (vCA1) projections to the amygdala are necessary for contextual fear memory. Here we used in vivo Ca2+ imaging in mice to assess the temporal dynamics by which ensembles of vCA1 neurons mediate encoding and retrieval of contex
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d6a11eb4be6a3688f5b3887870ab807
http://link.springer.com/article/10.1038/s41467-020-17270-w
http://link.springer.com/article/10.1038/s41467-020-17270-w
Autor:
Li Li, Steven C. Wyler, Luis A. León-Mercado, Baijie Xu, Youjin Oh, null Swati, Xiameng Chen, Rong Wan, Amanda G. Arnold, Lin Jia, Guanlin Wang, Katherine Nautiyal, René Hen, Jong-Woo Sohn, Chen Liu
Publikováno v:
The Journal of experimental medicine. 219(8)
Triptans are a class of commonly prescribed antimigraine drugs. Here, we report a previously unrecognized role for them to suppress appetite in mice. In particular, frovatriptan treatment reduces food intake and body weight in diet-induced obese mice
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d08a65fcac0756ddfdf9526eed5598
https://pubmed.ncbi.nlm.nih.gov/35796804
https://pubmed.ncbi.nlm.nih.gov/35796804
Autor:
Kenji F. Tanaka, Ko Matsui, Takuya Sasaki, Hiromi Sano, Shouta Sugio, Kai Fan, René Hen, Junichi Nakai, Yuchio Yanagawa, Hidetoshi Hasuwa, Masaru Okabe, Karl Deisseroth, Kazuhiro Ikenaka, Akihiro Yamanaka
Publikováno v:
Cell Reports, Vol 2, Iss 2, Pp 397-406 (2012)
Optogenetics has been enthusiastically pursued in recent neuroscience research, and the causal relationship between neural activity and behavior is becoming ever more accessible. Here, we established knockin-mediated enhanced gene expression by impro
Externí odkaz:
https://doaj.org/article/80497b0c34204d25abbad65903c189a8