Zobrazeno 1 - 10
of 650
pro vyhledávání: '"Ren, Lai"'
Autor:
Jingmei Hu, Yalan Han, Anna Luo, Hao Zhang, Lifeng Tian, Huajun Cai, Beiru Xue, Ren Lai, Lei Luo
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-10 (2024)
Abstract Otopetrin 1 (OTOP1) is a proton-activated channel crucial for animals’ perception of sour taste. Despite its significance, the gating mechanism of OTOP1 remains poorly understood. Here, we demonstrate that carvacrol activates the mouse OTO
Externí odkaz:
https://doaj.org/article/5269743aa339470fa32aa995c6ec895b
Publikováno v:
Feed Research. 2024, Vol. 47 Issue 18, p63-69. 7p.
Autor:
Xiaopeng Tang, Mingqian Fang, Ruomei Cheng, Junkun Niu, Xiaoshan Huang, Kuanhong Xu, Gan Wang, Yang Sun, Zhiyi Liao, Zhiye Zhang, James Mwangi, Qiumin Lu, Aili Wang, Longbao Lv, Chao Liu, Yinglei Miao, Ren Lai
Publikováno v:
Research, Vol 7 (2024)
Cross-talks (e.g., host-driven iron withdrawal and microbial iron uptake between host gastrointestinal tract and commensal microbes) regulate immunotolerance and intestinal homeostasis. However, underlying mechanisms that regulate the cross-talks rem
Externí odkaz:
https://doaj.org/article/1e442ea016454a42946cd444abbd68b0
Autor:
Yangyue Ni, Ruiyan Xiong, Yuxiao Zhu, Ning Luan, Chuanxin Yu, Kun Yang, Huiquan Wang, Xuejun Xu, Yuxuan Yang, Siyu Sun, Liyun Shi, Jon Rob Padde, Lin Chen, Lu Chen, Min Hou, Zhipeng Xu, Ren Lai, Minjun Ji
Publikováno v:
EBioMedicine, Vol 95, Iss , Pp 104751- (2023)
Summary: Background: Regulatory T cells (Tregs) can alleviate the development of autoimmune and inflammatory diseases, thereby proposing their role as a new therapeutic strategy. Parasitic helminths have co-evolved with hosts to generate immunologica
Externí odkaz:
https://doaj.org/article/7488dbdd392e4d18aa028f6c94d9f584
Autor:
Lifeng Tian, Hao Zhang, Shilong Yang, Anna Luo, Peter Muiruri Kamau, Jingmei Hu, Lei Luo, Ren Lai
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-10 (2023)
pH sensation is critical for survival of vertebrates. Here, authors found six vertebrate OTOP1 channels that were highly conserved and directly activated by extracellular alkali. Key mutations of OTOP1 reduced alkali affinity without affecting acid a
Externí odkaz:
https://doaj.org/article/e0596dfd3c934c23975fa01e8e545f25
Publikováno v:
Molecules, Vol 29, Iss 1, p 35 (2023)
Spiders (Araneae), having thrived for over 300 million years, exhibit remarkable diversity, with 47,000 described species and an estimated 150,000 species in existence. Evolving with intricate venom, spiders are nature’s skilled predators. While on
Externí odkaz:
https://doaj.org/article/359ee5289e324479badbd6977fe812f8
Autor:
Gan Wang, Min Zhang, Ping Meng, Chengbo Long, Xiaodong Luo, Xingwei Yang, Yunfei Wang, Zhiye Zhang, James Mwangi, Peter Muiruri Kamau, Zhi Dai, Zunfu Ke, Yi Zhang, Wenlin Chen, Xudong Zhao, Fei Ge, Qiumin Lv, Mingqiang Rong, Dongsheng Li, Yang Jin, Xia Sheng, Ren Lai
Publikováno v:
Acta Pharmaceutica Sinica B, Vol 12, Iss 5, Pp 2268-2279 (2022)
Unlike healthy, non-transformed cells, the proteostasis network of cancer cells is taxed to produce proteins involved in tumor development. Cancer cells have a higher dependency on molecular chaperones to maintain proteostasis. The chaperonin T-compl
Externí odkaz:
https://doaj.org/article/283910d86bdf442eac0cd9da6b6292df
Autor:
Mohammad Qorbani, Amr Sabbah, Ying-Ren Lai, Septia Kholimatussadiah, Shaham Quadir, Chih-Yang Huang, Indrajit Shown, Yi-Fan Huang, Michitoshi Hayashi, Kuei-Hsien Chen, Li-Chyong Chen
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-8 (2022)
Systematically study of in-plane intrinsic defects and edge atoms is important to guide the design of low-dimensional photocatalysts. Here the authors investigate photocatalytic CO2 reduction to CH4 over reconstructed edge atoms of monolayer semicond
Externí odkaz:
https://doaj.org/article/ed763eed48574f3db65c9721044fa55e
Autor:
Li-Na Cha, Juan Yang, Jin-Ai Gao, Xin Lu, Xiao-Long Chang, Thuku, Rebecca Caroline, Qi Liu, Qiu-Min Lu, Dong-Sheng Li, Ren Lai, Ming-Qian Fang
Publikováno v:
Zoological Research; 2024, Vol. 45 Issue 5, p1001-1012, 12p
Publikováno v:
Biomolecules, Vol 13, Iss 10, p 1453 (2023)
With the increase in drug-resistant bacteria, new antibacterial drugs have emerged as a prominent area of research and development. Antimicrobial peptides (AMPs), as innate immune agents, have garnered significant attention due to their potent, rapid
Externí odkaz:
https://doaj.org/article/b49832bbb31b4fbdb76d2da0076cd151