Zobrazeno 1 - 10
of 118
pro vyhledávání: '"Remus T Dame"'
Autor:
Samuel Schwab, Yimin Hu, Bert van Erp, Marc K. M. Cajili, Marcus D. Hartmann, Birte Hernandez Alvarez, Vikram Alva, Aimee L. Boyle, Remus T. Dame
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Histones are important chromatin-organizing proteins in eukaryotes and archaea. They form superhelical structures around which DNA is wrapped. Recent studies have shown that some archaea and bacteria contain alternative histones that exhibit
Externí odkaz:
https://doaj.org/article/ee1726d5e7934d70aae55b1a914800b2
Publikováno v:
PLoS Genetics, Vol 14, Iss 9, p e1007582 (2018)
The genomes of all organisms throughout the tree of life are compacted and organized in chromatin by association of chromatin proteins. Eukaryotic genomes encode histones, which are assembled on the genome into octamers, yielding nucleosomes. Post-tr
Externí odkaz:
https://doaj.org/article/3eb68035816841478250e8f736b1533b
Autor:
Ramon A van der Valk, Jocelyne Vreede, Liang Qin, Geri F Moolenaar, Andreas Hofmann, Nora Goosen, Remus T Dame
Publikováno v:
eLife, Vol 6 (2017)
Bacteria frequently need to adapt to altered environmental conditions. Adaptation requires changes in gene expression, often mediated by global regulators of transcription. The nucleoid-associated protein H-NS is a key global regulator in Gram-negati
Externí odkaz:
https://doaj.org/article/7e8de8306837484288f8eca19e55465f
Autor:
Kiran Chintakayala, Shivani S Singh, Amanda E Rossiter, Rajesh Shahapure, Remus T Dame, David C Grainger
Publikováno v:
PLoS Genetics, Vol 9, Iss 1, p e1003152 (2013)
The Escherichia coli curved DNA binding protein A (CbpA) is a poorly characterised nucleoid associated factor and co-chaperone. It is expressed at high levels as cells enter stationary phase. Using genetics, biochemistry, and genomics, we have examin
Externí odkaz:
https://doaj.org/article/5ffb1e2368324accbb2dddc8776fa0d6
Publikováno v:
PLoS Genetics, Vol 7, Iss 6, p e1002123 (2011)
The Escherichia coli chromosome is organized into four macrodomains, the function and organisation of which are poorly understood. In this review we focus on the MatP, SeqA, and SlmA proteins that have recently been identified as the first examples o
Externí odkaz:
https://doaj.org/article/b17659bd93e040ce853eaa26be49f20f
Autor:
Fatema-Zahra M. Rashid, Frédéric G. E. Crémazy, Andreas Hofmann, David Forrest, David C. Grainger, Dieter W. Heermann, Remus T. Dame
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-25 (2023)
Abstract Nucleoid associated proteins (NAPs) maintain the architecture of bacterial chromosomes and regulate gene expression. Thus, their role as transcription factors may involve three-dimensional chromosome re-organisation. While this model is supp
Externí odkaz:
https://doaj.org/article/e5591af993724439831c95bd12cafc31
Autor:
Sapir Ofer, Fabian Blombach, Amanda M. Erkelens, Declan Barker, Zoja Soloviev, Samuel Schwab, Katherine Smollett, Dorota Matelska, Thomas Fouqueau, Nico van der Vis, Nicholas A. Kent, Konstantinos Thalassinos, Remus T. Dame, Finn Werner
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract In eukaryotes, histone paralogues form obligate heterodimers such as H3/H4 and H2A/H2B that assemble into octameric nucleosome particles. Archaeal histones are dimeric and assemble on DNA into ‘hypernucleosome’ particles of varying sizes
Externí odkaz:
https://doaj.org/article/bc8d288a4e11401aafac8f1923d0ab56
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
In archaea, histones play a role in genome compaction and are involved in transcription regulation. Whereas archaeal histones bind DNA without sequence specificity, they bind preferentially to DNA containing repeats of alternating A/T and G/C motifs.
Externí odkaz:
https://doaj.org/article/5b0b41d6b1564249a77384b1633019b8
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Bacteria use specific silencing proteins to prevent spurious transcription of horizontally acquired DNA. Here, Forrest et al. describe differences in silencing strategies between E. coli and Bacillus subtilis, driven by the respective specificities o
Externí odkaz:
https://doaj.org/article/b2c4ce862b7448de9dd5acdab4432acc
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Architectural DNA–binding proteins are involved in many important DNA transactions by virtue of their ability to change DNA conformation. Histone-like protein from E. coli strain U93, HU, is one of the most studied bacterial architectural
Externí odkaz:
https://doaj.org/article/fd07cee0f0fd48a4b18836862b76e6ba