Zobrazeno 1 - 10
of 397
pro vyhledávání: '"Remus T"'
Autor:
Samuel Schwab, Yimin Hu, Bert van Erp, Marc K. M. Cajili, Marcus D. Hartmann, Birte Hernandez Alvarez, Vikram Alva, Aimee L. Boyle, Remus T. Dame
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-13 (2024)
Abstract Histones are important chromatin-organizing proteins in eukaryotes and archaea. They form superhelical structures around which DNA is wrapped. Recent studies have shown that some archaea and bacteria contain alternative histones that exhibit
Externí odkaz:
https://doaj.org/article/ee1726d5e7934d70aae55b1a914800b2
Autor:
Fatema-Zahra M. Rashid, Frédéric G. E. Crémazy, Andreas Hofmann, David Forrest, David C. Grainger, Dieter W. Heermann, Remus T. Dame
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-25 (2023)
Abstract Nucleoid associated proteins (NAPs) maintain the architecture of bacterial chromosomes and regulate gene expression. Thus, their role as transcription factors may involve three-dimensional chromosome re-organisation. While this model is supp
Externí odkaz:
https://doaj.org/article/e5591af993724439831c95bd12cafc31
Autor:
Sapir Ofer, Fabian Blombach, Amanda M. Erkelens, Declan Barker, Zoja Soloviev, Samuel Schwab, Katherine Smollett, Dorota Matelska, Thomas Fouqueau, Nico van der Vis, Nicholas A. Kent, Konstantinos Thalassinos, Remus T. Dame, Finn Werner
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-16 (2023)
Abstract In eukaryotes, histone paralogues form obligate heterodimers such as H3/H4 and H2A/H2B that assemble into octameric nucleosome particles. Archaeal histones are dimeric and assemble on DNA into ‘hypernucleosome’ particles of varying sizes
Externí odkaz:
https://doaj.org/article/bc8d288a4e11401aafac8f1923d0ab56
Publikováno v:
Frontiers in Microbiology, Vol 14 (2023)
In archaea, histones play a role in genome compaction and are involved in transcription regulation. Whereas archaeal histones bind DNA without sequence specificity, they bind preferentially to DNA containing repeats of alternating A/T and G/C motifs.
Externí odkaz:
https://doaj.org/article/5b0b41d6b1564249a77384b1633019b8
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-13 (2022)
Bacteria use specific silencing proteins to prevent spurious transcription of horizontally acquired DNA. Here, Forrest et al. describe differences in silencing strategies between E. coli and Bacillus subtilis, driven by the respective specificities o
Externí odkaz:
https://doaj.org/article/b2c4ce862b7448de9dd5acdab4432acc
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)
Abstract Architectural DNA–binding proteins are involved in many important DNA transactions by virtue of their ability to change DNA conformation. Histone-like protein from E. coli strain U93, HU, is one of the most studied bacterial architectural
Externí odkaz:
https://doaj.org/article/fd07cee0f0fd48a4b18836862b76e6ba
Autor:
Chao Du, Joost Willemse, Amanda M. Erkelens, Victor J. Carrion, Remus T. Dame, Gilles P. van Wezel
Publikováno v:
mSystems, Vol 7, Iss 3 (2022)
ABSTRACT Bacterial chromosome structure is, to a great extent, organized by a diverse group of proteins collectively referred to as nucleoid-associated proteins (NAPs). Many NAPs have been well studied in Streptomyces, including Lsr2, HupA, HupS, and
Externí odkaz:
https://doaj.org/article/bd447d8e4db64f64ac5a5a4cf038baa5
Autor:
Benjamin R. Gilbert, Zane R. Thornburg, Vinson Lam, Fatema-Zahra M. Rashid, John I. Glass, Elizabeth Villa, Remus T. Dame, Zaida Luthey-Schulten
Publikováno v:
Frontiers in Molecular Biosciences, Vol 8 (2021)
JCVI-syn3A is a genetically minimal bacterial cell, consisting of 493 genes and only a single 543 kbp circular chromosome. Syn3A’s genome and physical size are approximately one-tenth those of the model bacterial organism Escherichia coli’s, and
Externí odkaz:
https://doaj.org/article/275f892b8aea4872ababbebf2f3bc710
Autor:
Remus T. Dame
Publikováno v:
Microorganisms, Vol 9, Iss 11, p 2406 (2021)
A typical bacterial cell is micron-sized and contains a genome several million base pairs in length [...]
Externí odkaz:
https://doaj.org/article/dbf1bfa19c3043989a3fcc27c27bead6
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 24, p 9553 (2020)
HU is a nucleoid-associated protein expressed in most eubacteria at a high amount of copies (tens of thousands). The protein is believed to bind across the genome to organize and compact the DNA. Most of the studies on HU have been carried out in a s
Externí odkaz:
https://doaj.org/article/e5f29c4850104e57ab9379bfb5009c51