Zobrazeno 1 - 10
of 139
pro vyhledávání: '"Remus M Berretta"'
Autor:
Yijun Yang, Jaslyn Johnson, Constantine D. Troupes, Eric A. Feldsott, Lindsay Kraus, Emily Megill, Zilin Bian, Ngefor Asangwe, Tabito Kino, Deborah M. Eaton, Tao Wang, Marcus Wagner, Lena Ma, Christopher Bryan, Markus Wallner, Hajime Kubo, Remus M. Berretta, Mohsin Khan, Hong Wang, Raj Kishore, Steven R. Houser, Sadia Mohsin
Publikováno v:
Redox Biology, Vol 67, Iss , Pp 102909- (2023)
Few therapies have produced significant improvement in cardiac structure and function after ischemic cardiac injury (ICI). Our possible explanation is activation of local inflammatory responses negatively impact the cardiac repair process following i
Externí odkaz:
https://doaj.org/article/f68a1e3939344780bdcabe697059e9a3
Autor:
Thomas E. Sharp, III, BA, Hajime Kubo, PhD, Remus M. Berretta, BS, Timothy Starosta, BS, Markus Wallner, MD, PhD, Giana J. Schena, BS, Alexander R. Hobby, BS, Daohai Yu, PhD, Danielle M. Trappanese, PhD, Jon C. George, MD, Jeffery D. Molkentin, PhD, Steven R. Houser, PhD
Publikováno v:
JACC: Basic to Translational Science, Vol 2, Iss 6, Pp 669-683 (2017)
Inotropic support is often required to stabilize the hemodynamics of patients with acute decompensated heart failure; while efficacious, it has a history of leading to lethal arrhythmias and/or exacerbating contractile and energetic insufficiencies.
Externí odkaz:
https://doaj.org/article/dd3c3f7a8fed47668b3c56e6c1ad9062
Autor:
Alaina L. Headrick, Jaslyn Johnson, Timothy A. McKinsey, Giana Schena, Yijun Yang, Sadia Mohsin, Deborah M Eaton, Raj Kishore, Keith A. Koch, John W. Elrod, Steven R. Houser, Hajime Kubo, Remus M. Berretta, Alycia N Hildebrand, Emma K Murray
Publikováno v:
Am J Physiol Heart Circ Physiol
Heart failure is the one of the leading causes of death in the United States. Heart failure is a complex syndrome caused by numerous diseases, including severe myocardial infarction (MI). MI occurs after an occlusion of a cardiac artery causing downs
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876566a6f6474635de6efedc48a6a574
https://doi.org/10.1152/ajpheart.00197.2021
https://doi.org/10.1152/ajpheart.00197.2021
Autor:
Deborah M. Eaton, Remus M. Berretta, Jacqueline E. Lynch, Joshua G. Travers, Ryan D. Pfeiffer, Michelle L. Hulke, Huaqing Zhao, Alexander R. H. Hobby, Giana Schena, Jaslyn P. Johnson, Markus Wallner, Edward Lau, Maggie P. Y. Lam, Kathleen C. Woulfe, Nathan R. Tucker, Timothy A. McKinsey, Marla R. Wolfson, Steven R. Houser
Publikováno v:
American journal of physiology. Heart and circulatory physiology. 323(4)
Approximately 50% of all heart failure (HF) diagnoses can be classified as HF with preserved ejection fraction (HFpEF). HFpEF is more prevalent in females compared with males, but the underlying mechanisms are unknown. We previously showed that press
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0533c0ec3093f75dbffdca87ff1e9495
https://pubmed.ncbi.nlm.nih.gov/36053749
https://pubmed.ncbi.nlm.nih.gov/36053749
Autor:
John W. Elrod, Steven R. Houser, Markus Wallner, Remus M. Berretta, Dhanendra Tomar, Anh T Huynh, Joanne F Garbincius, Deborah M Eaton, Emma K Murray, Devin W. Kolmetzky, Andrew A. Gibb
Publikováno v:
JACC: Basic to Translational Science
Visual Abstract
Highlights • Early cardiac mitochondrial dysfunction is mediated by transcriptional down-regulation of the mitochondrial proteome. • Comprehensive metabolic remodeling is conserved throughout HFpEF progression and includes in
Highlights • Early cardiac mitochondrial dysfunction is mediated by transcriptional down-regulation of the mitochondrial proteome. • Comprehensive metabolic remodeling is conserved throughout HFpEF progression and includes in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::474acd63270db1077349e2d878112f6b
https://doi.org/10.1016/j.jacbts.2021.07.004
https://doi.org/10.1016/j.jacbts.2021.07.004
Autor:
Daohai Yu, Victor Rizzo, Xiongwen Chen, Jonathan P. Lambert, Markus Wallner, Abdelkarim Sabri, Jaslyn Johnson, Carlos Manuel Romero, Yijun Yang, Claire Poulet, Julia Gorelik, Andrew A. Gibb, Polina Gross, Jose L. Sanchez-Alonso, Joanne F Garbincius, Remus M. Berretta, John W. Elrod, Deborah M Eaton, Erdem Varol, Hajime Kubo, Carla Lucarelli, Jean Ross, Steven R. Houser, Eric Feldsott
Publikováno v:
Circulation Research. 128:92-114
Rationale: Ca 2+ -induced Ca 2+ release (CICR) in normal hearts requires close approximation of L-type calcium channels (LTCCs) within the transverse tubules (T-tubules) and RyR (ryanodine receptors) within the junctional sarcoplasmic reticulum. CICR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8f26ec0029d7f615793680e9749ea350
https://doi.org/10.1161/circresaha.119.315715
https://doi.org/10.1161/circresaha.119.315715
Autor:
David M. Harris, Kenneth B. Margulies, Xin Zhang, Xiongwen Chen, Xiaoying Zhang, Remus M. Berretta, Yijia Li, Valentino Piacentino, Steven R. Houser
Publikováno v:
Channels. 14:231-245
Low voltage activated (ICa-LVA) calcium currents including Cav1.3 and T-type calcium current (ICa-T) have not been reported in adult human left ventricular myocytes (HLVMs). We tried to examine the...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6a7482fa775780298515dc44d3fe1e2f
https://doi.org/10.1080/19336950.2020.1794420
https://doi.org/10.1080/19336950.2020.1794420
Autor:
Deborah M Eaton, Remus M Berretta, Jacqueline E Lynch, Joshua G Travers, Kathleen C Woulfe, Ryan D Pfeiffer, Michelle L Hulke, Alexander R Hobby, Giana Schena, Jaslyn P Johnson, Markus Wallner, Nathan R Tucker, Timothy A McKinsey, Marla R Wolfson, Steven R Houser
Publikováno v:
Circulation. 144
Introduction: Approximately 50% of all heart failure (HF) diagnoses can be classified as HF with preserved ejection fraction (HFpEF), which has no FDA approved therapies. HFpEF is more prevalent in females compared to males, but the underlying mechan
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2981644644f17732bcdc8bff808d5c4
https://doi.org/10.1161/circ.144.suppl_1.8955
https://doi.org/10.1161/circ.144.suppl_1.8955
Autor:
Jaslyn Johnson, Yijun Yang, Polina Gross, Deborah Eaton, Giana Schena, Remus M Berretta, Hajime KUBO, Sadia Mohsin, Ying Tian, Steven R Houser
Publikováno v:
Circulation. 144
Rationale: The adult mammalian heart has a very limited capacity to regenerate cardiomyocytes that die from pathological damage. Several studies suggest that those few new myocytes found after injury are derived from pre-existing cardiomyocytes. A re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fa96f092a3cb7012d8692893a657649d
https://doi.org/10.1161/circ.144.suppl_1.14091
https://doi.org/10.1161/circ.144.suppl_1.14091
Autor:
Timothy A. McKinsey, Jaslyn Johnson, Kathleen C. Woulfe, Giana Schena, Steven R. Houser, Jacqueline E Lynch, Joshua G Travers, Alexander R Hobby, Deborah M Eaton, M. Wallner, Marla R. Wolfson, Remus M. Berretta
Publikováno v:
Circulation Research. 129
Rationale: Heart Failure with preserved Ejection Fraction (HFpEF) accounts for approximately 50% of all HF diagnoses with no FDA approved therapies. HFpEF is more prevalent in females versus males, but the mechanisms driving the development of HFpEF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::303b5ed8eec01aa83fd7156b9c4644ce
https://doi.org/10.1161/res.129.suppl_1.p411
https://doi.org/10.1161/res.129.suppl_1.p411