Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Remo Weck"'
Publikováno v:
ChemistryOpen, Vol 8, Iss 9, Pp 1183-1189 (2019)
Abstract The reactivity and selectivity of iridium(I) catalysed hydrogen isotope exchange (HIE) reactions can be varied by using wide range of reaction temperatures. Herein, we have done a detailed comparison study with common iridium(I) catalysts (1
Externí odkaz:
https://doaj.org/article/fd45a41c3a814e2fa5d3bd8e67631e5d
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals.
Autor:
Carla Marie Stork, Remo Weck, Mégane Valero, Henrik Kramp, Stefan Güssregen, Siegfried R. Waldvogel, Anna Sib, Volker Derdau
Publikováno v:
Angewandte Chemie International Edition.
Autor:
Patrick Morawietz, Remo Weck, Andrew A. Scholte, Jens Atzrodt, Stefan Güssregen, Volker Derdau
Publikováno v:
Green Chemistry. 24:4824-4829
Hydrogen isotope exchange reactions with iridium(i) catalyst [(COD)Ir(IMes)(PPh3)]X 2 with significantly increased (up to 7 fold) radiochemical yields (RCY) in tritium gas reactions are reported.
Autor:
Jennifer Blass, Thomas Kruissink, Mégane Valero, Remo Weck, Stefan Güssregen, Alleyn T. Plowright, Volker Derdau
Publikováno v:
Angewandte Chemie International Edition
Angewandte Chemie (International Ed. in English)
Angewandte Chemie (International Ed. in English)
An assessment of the C−H activation catalyst [(COD)Ir(IMes)(PPh3)]PF6 (COD=1,5‐cyclooctadiene, IMes=1,3‐bis(2,4,6‐trimethylphenyl)imidazol‐2‐ylidene) in the deuteration of phenyl rings containing different functional directing groups is d
Autor:
Volker Derdau, Nils Rackelmann, Armin Bauer, Remo Weck, Anurag Mishra, Fabien Legros, Patricia Fernandez-Rodriguez, Christoph Pöverlein, María Méndez, Sven Ruf, Martin Sandvoss, Helena Mora-Radó
Publikováno v:
Chemistry (Weinheim an der Bergstrasse, Germany). 26(56)
Hydrogen isotopically labelled compounds are essential diagnostic tools in drug research and development, as they provide vital information about the biological metabolism of drug candidates and their metabolites. Herein we report a photoredox-initia
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 61:895-902
Radiolabelled azidophenyl analogues can make powerful photoaffinity probes for the identification of molecular targets. We describe our efforts to prepare tritiated azidophenyl analogues of the taxols cabazitaxel and docetaxel. Late-stage tritiation
Autor:
Mégane Valero, Volker Derdau, Remo Weck, Kristof Jess, Annina Burhop, Matthias Tamm, Jens Atzrodt
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals
We have developed a novel and efficient iridium-catalyzed hydrogen isotope exchange reaction method with secondary and tertiary sulfonamides at ambient temperatures. Furthermore N-oxides and phosphonamides have been successfully applied in hydrogen i
Publikováno v:
European Journal of Organic Chemistry. 2017:1418-1424
For the first time we report the optimized hydrogen-isotope exchange (HIE) conditions for the selective aromatic deuteriation of various sulfonylureas and tertiary sulfonamides, as well as for a broad range of secondary sulfonamides. Based on a compr
Autor:
Volker Derdau, Remo Weck, Peter G. Jones, Matthias Tamm, Matthias Freytag, Kristof Jess, Jens Atzrodt
Publikováno v:
Advanced Synthesis & Catalysis. 359:629-638
Phenylene-bridged hybrid phosphine-imidazolin-2-imine RP,NR′ ligands (R=Ph, Cy, i-Pr, t-Bu; R′=Me, i-Pr) were prepared from 1,2-dibromobenzene by palladium-catalyzed C–N coupling with 1,3,4,5-tetramethylimidazolin-2-imine or 1,3-diisopropyl-4,5