Zobrazeno 1 - 10
of 105
pro vyhledávání: '"Remo Fumagalli"'
Autor:
Remo Fumagalli, Cesare R. Sirtori
Publikováno v:
Atherosclerosis. 186:1-11
A number of reports have indicated that both lowering low density lipoprotein (LDL)-cholesterol and raising high density lipoprotein (HDL)-cholesterol can result in significant cardiovascular benefit, both in terms of reduction of events and also, to
Publikováno v:
European Journal of Pharmacology. 355:77-83
Picotamide is an antiplatelet drug with a peculiar dual mechanism of action: it inhibits thromboxane A2 synthase and antagonizes the pharmacological responses mediated by thromboxane A2 receptor. We investigated the in vitro effect of picotamide on s
Autor:
Pascal Pfister, Alberto Corsini, Franco Pazzucconi, Remo Fumagalli, Lorenzo Arnaboldi, Cesare R. Sirtori, Rodolfo Paoletti
Publikováno v:
Journal of Cardiovascular Pharmacology. 31:773-778
The beneficial effects of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) on coronary events have generally been attributed to their hypocholesterolemic properties. Mevalonate and other intermediates of cholesterol synt
Autor:
Maurizio R. Soma, Elena Donetti, Chiara Teruzzi, Rodolfo Paoletti, Roberta Baetta, Alessandra Rossi, Carmen Comparato, Remo Fumagalli, Monica Calore
Publikováno v:
Pharmacological Research. 36:115-121
The in vitro and in vivo activity of atorvastatin and other 3-hydroxy-3-methylglutaryl coenzyme A (HMGCoA) reductase inhibitors (fluvastatin, pravastatin and simvastatin) has been investigated. Atorvastatin, fluvastatin, pravastatin and simvastatin c
Autor:
A. Sartani, M. Bonfatti, M. R. Accomazzo, P. Quarato, Rodolfo Paoletti, Alberto Corsini, Simonetta Nicosia, M. Raiteri, Remo Fumagalli, R. Testa
Publikováno v:
Journal of Cardiovascular Pharmacology. 28:687-694
The in vitro effects were investigated of the new dihydropyridine calcium antagonist (CA) lercanidipine and its enantiomers on arterial myocyte (smooth muscle cell; SMC) migration and proliferation as related to L-type calcium channel inhibition. Ler
Autor:
Charles C. Hsi, Juey-Jen Hwang, Catherine Metayer, Silvana Müller, P. Toutouzas, Steven S. Coughlin, Creusa M.R. Dalbo, Franco Bernini, Hayder Omran, D. Babalis, Anne Pauline Schroeder, Elvira Jelen, Remo Fumagalli, N. Leflcos, Randolph P. Martin, Søren Larsen, Reinaldo B. Bestetti, Mogens Lytken Larsen, Nobuyuki Ohte, Victor Parsonnet, H. Schäfer, Nobuyoshi Tomioka, Dimitri Novitzky, Takeshi Hashimoto, Bent Østergaard Kristensen, Russell F. Stahl, Eran Leitersdorf, Hiroshi Akawawa, Santiago Ewig, Fujio Ohkawa, Björn W. Karlson, Torsten Bauer, Keiji Yamamoto, Margareta Sjölin, Mamoru Suzaki, Daniel Smith, Stefano Bellosta, Takao Fujinami, Yi-Heng Li, Hideyuki Fujikawa, Hector Fontanet, Kevin G. Shortt, Janice M. Belle Isle, Henrik Egeblad, Sachie Akita, Kenji Kobayashi, Alan H. Auerbach, Angela Bång, Michael Snyder, Saeed Ahmad, Benedikte Haastrup, Uichi Ikeda, Pierangelo Quarato, Yukihiro Hojo, Annebirthe Bo Hansen, Alberto Corsini, V. Votteas, Hitomi Narita, Dalmo Correia Filho, A. Manolis, Johan Herlitz, Frances J. Mather, Allan Rohold, Chiharu Kishimoto, Berndt Lüderitz, Carlos Alberto Arruda, Kwan-Lih Hsu, D. Tsagadopoulos, Jer-Min Lin, Woodfin. Cobbs, Kazuyuki Shimada, Yuji Hiraoka, H. Antonakoudis, Torben Haghfelt, Hitoshi Takada, T. Makris, Rodolfo Paoletti, Thomas Bartel, G. Vyssoulis, Hiromichi Sekiguchi, Mary Lynch, Antonio M. Gotto, Babs R. Soller, A. Achimastos, Raimund Erbel, Robin L. Miller, Maurizio R. Soma, Iris Shviro, Elena Donetti, Gert Baumann, Yung-Zu Tseng, Nicholas Coblio, Etsuko Maruya, Olavo C. Freitas
Publikováno v:
Cardiology. 87:I-VI
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 15:1352-1358
Abstract We previously reported that mevalonate starvation elicited by hydroxymethyl glutaryl coenzyme A (HMG-CoA) reductase inhibitors reduced cholesterol accumulation promoted in murine macrophages by acetylated LDL (AcLDL). In the present study we
Publikováno v:
Arteriosclerosis, Thrombosis, and Vascular Biology. 15:420-428
Abstract The major relation existing between cell growth and cholesterol homeostasis prompted us to investigate the effect of 26-aminocholesterol (26-NH 2 ), 27-hydroxycholesterol (27-OH), and 25-hydroxycholesterol (25-OH) on these cellular events. T
Autor:
Alberto Corsini, Remo Fumagalli, Stefano Bellosta, Beitz J, Rodolfo Paoletti, P Grignaffini, Mest Hj
Publikováno v:
Cytotechnology. 11(Suppl 1)
The effect of trapidil derivative AR12456 on intracellular cholesterol metabolism was investigated in human hepatoma cell line HepG2. AR12456 enhanced the uptake and degradation of(125)I-LDL in a dose-dependent manner. The drug inhibited cholesterol
Autor:
Rodolfo Paoletti, Remo Fumagalli, Joel D. Morrisett, Michele Meschia, P. G. Crosignani, F. Bruschi, Maurizio R. Soma
Publikováno v:
Chemistry and Physics of Lipids. :345-350
Lipoprotein(a) (Lp(a)) plasma concentrations in Caucasian populations are classified as a quantitative genetic trait. Although the prevailing view has been that Lp(a) levels are affected by age and gender, recent data are beginning to indicate otherw