Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Remo D. Spescha"'
Autor:
Alexander Breitenstein, Christophe A Wyss, Remo D Spescha, Fabian C Franzeck, Danielle Hof, Meliana Riwanto, Matthias Hasun, Alexander Akhmedov, Arnold von Eckardstein, Willibald Maier, Ulf Landmesser, Thomas F Lüscher, Giovanni G Camici
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53106 (2013)
BACKGROUND: Inflammation plays a key role in atherosclerosis. Sirt1 regulates transcription factors involved in inflammatory processes and blunts atherosclerosis in mice. However, its role in humans remains to be defined. This study was therefore des
Externí odkaz:
https://doaj.org/article/91504a2fa2a84a3dbd9075311dc1e0b1
Autor:
Candela Diaz-Cañestro, Fabrizio Montecucco, Gianluigi Savarese, Thomas F. Lüscher, Giacomo Giacalone, Remo D. Spescha, Luka Kulic, Martin F Reiner, Jürg H. Beer, Daniel S. Gaul, Luca Liberale, Maria Sessa, Nicole R. Bonetti, Gerd A. Kullak-Ublick, Alexander Akhmedov, Christian M. Matter, Aurora Semerano, Heidi Amstalden, Roger M. Nitsch, Giovanni G. Camici, Rebecca Spescha, Sylvie Briand-Schumacher, Mario Merlini
Publikováno v:
J Cereb Blood Flow Metab
Lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) is implicated in cardiovascular disease by modulating apoptosis and oxidative stress. We hypothesized that LOX-1 may be involved in pathophysiology of stroke by mediating ischaemia/reper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65f57ba05cc2e578b03a56748300f11
https://doi.org/10.1177/0271678x18793266
https://doi.org/10.1177/0271678x18793266
Autor:
Martin F Reiner, Thomas F. Lüscher, Christine Lohmann, Francesco Paneni, Ariane Schaub Clerigue, Giovanni G. Camici, Juerg-Hans Beer, Jasmin Manz, Nicole R. Bonetti, Alexander Akhmedov, Thimoteus Speer, Simona Stivala, Sarah Costantino, Remo D. Spescha, Alexander Breitenstein, Erik W. Holy
Publikováno v:
Cardiovascular research
Aims The lectin-like oxLDL receptor-1 (LOX-1) promotes endothelial uptake of oxidized low-density lipoprotein (oxLDL) and plays an important role in atherosclerosis and acute coronary syndromes (ACS). However, its role in arterial thrombus formation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c5be651ffa2ff19edc0bc70dcfdda1ab
https://doi.org/10.1093/cvr/cvx015
https://doi.org/10.1093/cvr/cvx015
Autor:
Alexander Breitenstein, Remo D. Spescha, Thomas F. Lüscher, F.C. Tanner, Simon F. Stämpfli, Stephan Keller, Martin F Reiner, H.-J. Beer, Alexander Akhmedov, A. Schaub Clerigué, Giovanni G. Camici, Y. Shi
Publikováno v:
Thrombosis and haemostasis
SummaryDespite public awareness of its deleterious effects, smoking remains a major cause of death. Indeed, it is a risk factor for atherothrombotic complications and in line with this, the introduction of smoking ban in public areas reduced smoking-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::53814ceea7095649f7822dc1801d0074
https://doi.org/10.1160/th16-05-0351
https://doi.org/10.1160/th16-05-0351
Autor:
G G Camici, J H Beer, Christian M. Matter, Fabrizio Montecucco, Thomas F. Lüscher, Nicole R. Bonetti, Daniel S. Gaul, Martin F Reiner, Gerd A. Kullak-Ublick, Candela Diaz-Cañestro, Alexander Akhmedov, Gianluigi Savarese, Luca Liberale, Remo D. Spescha, Mario Merlini
Publikováno v:
European Heart Journal. 39
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7fa01abfefeaea658f67a8aad6d2d928
https://doi.org/10.1093/eurheartj/ehy565.p2494
https://doi.org/10.1093/eurheartj/ehy565.p2494
Autor:
Johannes Vogel, Luka Kulic, Muriel R Kaufmann, Giacomo Giacalone, Stephan Keller, Luca Peruzzotti-Jametti, Martin F Reiner, Thomas F. Lüscher, Roland H. Wenger, Aurora Semerano, Pavani Mocharla, Roger M. Nitsch, Martina Glanzmann, Remo D. Spescha, Maria Sessa, Jürg H. Beer, Jan Klohs, D. Rodriguez Gutierrez, N. Mendez-Carmona, Alexander Akhmedov, Nicolle Kränkel, Rebecca Derungs, Giovanni G. Camici, Gianluigi Savarese
Publikováno v:
EUROPEAN HEART JOURNAL
European Heart Journal, 36
European Heart Journal
European Heart Journal, 36
European Heart Journal
European Heart Journal, 36
ISSN:1522-9645
ISSN:0195-668X
ISSN:1522-9645
ISSN:0195-668X
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5f64d83ba711f92c68667d2853a11691
https://doi.org/10.1093/eurheartj/ehv140
https://doi.org/10.1093/eurheartj/ehv140
Autor:
Giovanni G. Camici, Stephan Keller, Nadine Lauinger, Michael Weller, Susanne Wegener, Ghazaleh Tabatabai, Matthias M. Wyss, Thomas F. Lüscher, Remo D. Spescha, Bruno Weber, Francesco Cosentino, Yi Shi, Roger M. Nitsch, Francesco Paneni, Christoph Hock
Publikováno v:
European heart journal
European Heart Journal
European Heart Journal
AIMS Stroke is a leading cause of morbidity and mortality and its incidence increases with age. Both in animals and in humans oxidative stress appears to play an important role in ischaemic stroke with or without reperfusion. The adaptor protein p66(
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ddaf9b8821a42fc3e341dd3fb61baa3
http://doc.rero.ch/record/297614/files/ehs331.pdf
http://doc.rero.ch/record/297614/files/ehs331.pdf
Autor:
Thomas F. Lüscher, Sokrates Stein, Christian M. Matter, Christoph H. Westphal, Christine Lohmann, Alexander Breitenstein, Remo D. Spescha, Erik W. Holy, Felix C. Tanner, Peter J. Elliott, Giovanni G. Camici, Alexander Akhmedov
Aims The mammalian silent information regulator-two 1 (Sirt1) blunts the noxious effects of cardiovascular risk factors such as type 2 diabetes mellitus and obesity. Nevertheless, the role of Sirt1 in regulating the expression of tissue factor (TF),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1b12608b0a0ee5d1a8a9f82aa867cc8
http://doc.rero.ch/record/302593/files/cvq339.pdf
http://doc.rero.ch/record/302593/files/cvq339.pdf
Autor:
Claudia Späni, Giovanni G. Camici, Rebecca Derungs, Anne Eckert, Christian Tackenberg, Amandine Grimm, Roger M. Nitsch, Fabian Wirth, Luka Kulic, Tobias Welt, Remo D. Spescha
The mammalian ShcA adaptor protein p66Shc is a key regulator of mitochondrial reactive oxygen species (ROS) production and has previously been shown to mediate amyloid β (Aβ)-peptide-induced cytotoxicity in vitro. Moreover, p66Shc is involved in ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0207cbc428b7a2fa645490db695ed11e
https://www.zora.uzh.ch/id/eprint/130304/
https://www.zora.uzh.ch/id/eprint/130304/
Autor:
Giovanni G. Camici, Stephan Keller, Branko Simic, Thomas F. Lüscher, Felix C. Tanner, Alexander Akhmedov, Fabienne Witassek, Martina Glanzmann, Remo D. Spescha
Publikováno v:
Hypertension
Increased cyclic stretch to the vessel wall, as observed in hypertension, leads to endothelial dysfunction through increased free radical production and reduced nitric oxide bioavailability. Genetic deletion of the adaptor protein p66 Shc protects mi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a71c67c251febd2a95b195b83c656acc