Zobrazeno 1 - 10 of 23 pro vyhledávání: '"Remmelt R. Schür"'
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Akademický článek
The Role of Stress and Mineralocorticoid Receptor Haplotypes in the Development of Symptoms of Depression and Anxiety During Adolescence
Autor: Hinke M. Endedijk, Stefanie A. Nelemans, Remmelt R. Schür, Marco P. M. Boks, Pol van Lier, Wim Meeus, Susan Branje, Christiaan H. Vinkers
Publikováno v: Frontiers in Psychiatry, Vol 11 (2020)
Adolescence is a critical developmental period characterized by heightened levels of depressive and anxiety symptoms. Experiencing chronic or environmental stress, for example, as a result of traumatic events or insensitive parenting, increases the r
Externí odkaz: https://doaj.org/article/27b307eb50304370abe9fc9cd02b3e5f
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2
Successful treatment of post-traumatic stress disorder reverses DNA methylation marks
Autor: Bart P. F. Rutten, Christiaan H. Vinkers, Alicia K. Smith, Elbert Geuze, Caroline M. Nievergelt, Sanne J.H. van Rooij, Eric Vermetten, Remmelt R. Schür, Mitzy Kennis, Marco P. Boks, Danny M Nispeling, Monica Uddin
Publikováno v: Molecular Psychiatry, 26(4). Nature Publishing Group
Vinkers, C H, Geuze, E, van Rooij, S J H, Kennis, M, Schür, R R, Nispeling, D M, Smith, A K, Nievergelt, C M, Uddin, M, Rutten, B P F, Vermetten, E & Boks, M P 2021, ' Successful treatment of post-traumatic stress disorder reverses DNA methylation marks ', Molecular Psychiatry, vol. 26, no. 4, pp. 1264–1271 . https://doi.org/10.1038/s41380-019-0549-3
Molecular Psychiatry, 26(4), 1264-1271. SPRINGERNATURE
Molecular Psychiatry, 26(4), 1264-1271. Nature Publishing Group
Epigenetic mechanisms play a role in the detrimental effects of traumatic stress and the development of post-traumatic stress disorder (PTSD). However, it is unknown whether successful treatment of PTSD restores these epigenetic marks. This study inv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9de1efa2cd083345ad6c21eb9c10e32d
https://research.vumc.nl/en/publications/5a4f323a-2c20-474e-9de9-a1614cb2fba6
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3
Multivariate genome-wide analysis of stress-related quantitative phenotypes
Autor: Eric Vermetten, Sara L. Pulit, Erwin Bekema, Christiaan H. Vinkers, Jurjen J. Luykx, Marie Malgaz, Jan H. Veldink, Kendrick E. van der Kust, Dick Schijven, Elbert Geuze, Jelena Medic, Remmelt R. Schür, Marco P. Boks
Publikováno v: Schijven, D, Geuze, E, Vinkers, C H, Pulit, S L, Schür, R R, Malgaz, M, Bekema, E, Medic, J, van der Kust, K E, Veldink, J H, Boks, M P, Vermetten, E & Luykx, J J 2019, ' Multivariate genome-wide analysis of stress-related quantitative phenotypes ', European Neuropsychopharmacology, vol. 29, no. 12, pp. 1354-1364 . https://doi.org/10.1016/j.euroneuro.2019.09.012
European Neuropsychopharmacology, 29(12), 1354-1364. Elsevier
European Neuropsychopharmacology, 29(12), 1354-1364. ELSEVIER
European Neuropsychopharmacology, 29(12), 1354. Elsevier
Exposure to traumatic stress increases the odds of developing a broad range of psychiatric conditions. Genetic studies targeting multiple stress-related quantitative phenotypes may shed light on mechanisms underlying vulnerability to psychopathology
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd4b1ebf18d50db0a32bdda06906808e
https://hdl.handle.net/1887/122426
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4
Acute stress effects on GABA and glutamate levels in the prefrontal cortex: A 7T 1H magnetic resonance spectroscopy study
Autor: D. W. J. Klomp, René S. Kahn, Vincent O. Boer, Remmelt R. Schür, Christiaan H. Vinkers, Marian Joëls, Marco P. Boks, Jannie P. Wijnen, Lotte C Houtepen
Publikováno v: Neuroimage: Clinical [E], 14, 195. Elsevier BV
NeuroImage: Clinical, Vol 14, Iss C, Pp 195-200 (2017)
There is ample evidence that the inhibitory GABA and the excitatory glutamate system are essential for an adequate response to stress. Both GABAergic and glutamatergic brain circuits modulate hypothalamus-pituitary-adrenal (HPA)-axis activity, and st
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1315a2e2a5e1347d11cd01fbf1d74324
https://doi.org/10.1016/j.nicl.2017.01.001
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5
The effect of genetic vulnerability and military deployment on the development of post-traumatic stress disorder and depressive symptoms
Autor: Murray B. Stein, Christiaan H. Vinkers, Remmelt R. Schür, Elbert Geuze, Dick Schijven, Jan H. Veldink, Bart P. F. Rutten, Marian Joëls, Jurjen J. Luykx, Marco P. Boks, Eric Vermetten
Publikováno v: Schür, R R, Schijven, D, Boks, M P, Rutten, B P F, Stein, M B, Veldink, J H, Joëls, M, Geuze, E, Vermetten, E, Luykx, J J & Vinkers, C H 2019, ' The effect of genetic vulnerability and military deployment on the development of post-traumatic stress disorder and depressive symptoms ', European Neuropsychopharmacology, vol. 29, no. 3, pp. 405-415 . https://doi.org/10.1016/j.euroneuro.2018.12.009
European Neuropsychopharmacology, 29(3), 405-415. ELSEVIER SCIENCE BV
European Neuropsychopharmacology, 29(3), 405. Elsevier
European Neuropsychopharmacology, 29(3), 405-415. Elsevier
Exposure to trauma strongly increases the risk to develop stress-related psychopathology, such as post-traumatic stress disorder (PTSD) or major depressive disorder (MDD). In addition, liability to develop these moderately heritable disorders is part
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::69dd121a5e73955ac6ba52891b444a84
https://hdl.handle.net/1887/122428
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6
Successful treatment of post-traumatic stress disorder reverses DNA methylation marks
Autor: Christiaan H, Vinkers, Elbert, Geuze, Sanne J H, van Rooij, Mitzy, Kennis, Remmelt R, Schür, Danny M, Nispeling, Alicia K, Smith, Caroline M, Nievergelt, Monica, Uddin, Bart P F, Rutten, Eric, Vermetten, Marco P, Boks
Publikováno v: Molecular psychiatry. 26(4)
Epigenetic mechanisms play a role in the detrimental effects of traumatic stress and the development of post-traumatic stress disorder (PTSD). However, it is unknown whether successful treatment of PTSD restores these epigenetic marks. This study inv
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::ad757c8837bedfa995d8bef20c8683db
https://pubmed.ncbi.nlm.nih.gov/31645664
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7
Brain GABA levels across psychiatric disorders: A systematic literature review and meta-analysis of1H-MRS studies
Autor: René S. Kahn, Luc W.R. Draisma, Dennis W. J. Klomp, Marco P. Boks, Jannie P. Wijnen, Martijn G.J.C. Koevoets, Christiaan H. Vinkers, Marian Joëls, Remmelt R. Schür
Publikováno v: Human Brain Mapping. 37:3337-3352
The inhibitory gamma-aminobutyric acid (GABA) system is involved in the etiology of most psychiatric disorders, including schizophrenia, autism spectrum disorder (ASD) and major depressive disorder (MDD). It is therefore not surprising that proton ma
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a5f9dd2f3e1fbfa0a7857172ba7d8120
https://doi.org/10.1002/hbm.23244
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8
Glucocorticoid receptor exon 1F methylation and the cortisol stress response in health and disease
Autor: Remmelt R. Schür, Marian Joëls, Lotte C Houtepen, Christiaan H. Vinkers, René S. Kahn, Marco P. Boks, Judith M.C. van Leeuwen
Publikováno v: Schür, R R, van Leeuwen, J M C, Houtepen, L C, Joëls, M, Kahn, R S, Boks, M P & Vinkers, C H 2018, ' Glucocorticoid receptor exon 1 F methylation and the cortisol stress response in health and disease ', Psychoneuroendocrinology, vol. 97, pp. 182-189 . https://doi.org/10.1016/j.psyneuen.2018.07.018
Psychoneuroendocrinology, 97, 182-189. PERGAMON-ELSEVIER SCIENCE LTD
Psychoneuroendocrinology, 97, 182. Elsevier Limited
Psychoneuroendocrinology, 97, 182-189. Elsevier Limited
Schür, R R, van Leeuwen, J M C, Houtepen, L C, Joëls, M, Kahn, R S, Boks, M P & Vinkers, C H 2018, ' Glucocorticoid receptor exon 1F methylation and the cortisol stress response in health and disease ', Psychoneuroendocrinology, vol. 97, pp. 182-189 . https://doi.org/10.1016/j.psyneuen.2018.07.018
Childhood trauma has been proposed to increase vulnerability to develop psychopathology in part through an altered cortisol stress response. Research in rats has suggested that this effect is mediated by methylation in the glucocorticoid receptor 17
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e26b3246ef188563404fc0fa609f02f
https://hdl.handle.net/1983/e2a3e409-2610-4343-aed6-4c81a98977c6
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9
Glucocorticoid receptor exon 1
Autor: Remmelt R, Schür, Judith M C, van Leeuwen, Lotte C, Houtepen, Marian, Joëls, René S, Kahn, Marco P, Boks, Christiaan H, Vinkers
Publikováno v: Psychoneuroendocrinology. 97
Childhood trauma has been proposed to increase vulnerability to develop psychopathology in part through an altered cortisol stress response. Research in rats has suggested that this effect is mediated by methylation in the glucocorticoid receptor 1
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::74afdb58dd7620ac669ca6ff952c39f6
https://pubmed.ncbi.nlm.nih.gov/30036796
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