Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Remko van Leeuwen"'
Autor:
Colin Bournez, Martijn Riool, Leonie de Boer, Robert A. Cordfunke, Leonie de Best, Remko van Leeuwen, Jan Wouter Drijfhout, Sebastian A. J. Zaat, Gerard J. P. van Westen
Publikováno v:
Antibiotics, Vol 12, Iss 4, p 725 (2023)
To combat infection by microorganisms host organisms possess a primary arsenal via the innate immune system. Among them are defense peptides with the ability to target a wide range of pathogenic organisms, including bacteria, viruses, parasites, and
Externí odkaz:
https://doaj.org/article/bba35ed07cc441348c3987da0c9147cf
Autor:
Yoanne D Mouwenda, Madeleine E Betouke Ongwe, Friederike Sonnet, Koen A Stam, Lucja A Labuda, Sophie De Vries, Martin P Grobusch, Frejus J Zinsou, Yabo J Honkpehedji, Jean-Claude Dejon Agobe, David J Diemert, Remko van Leeuwen, Maria E Bottazzi, Peter J Hotez, Peter G Kremsner, Jeffrey M Bethony, Simon P Jochems, Ayola A Adegnika, Marguerite Massinga Loembe, Maria Yazdanbakhsh
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009732 (2021)
Two hookworm vaccine candidates, Na-GST-1 and Na-APR-1, formulated with Glucopyranosyl Lipid A (GLA-AF) adjuvant, have been shown to be safe, well tolerated, and to induce antibody responses in a Phase 1 clinical trial (Clinicaltrials.gov NCT02126462
Externí odkaz:
https://doaj.org/article/74b241e8340f43ffaff17b49d024c36c
Autor:
Till Bärnighausen, Albrecht Jahn, Eva Annette Rehfuess, Ibrahim Abubakar, Kerstin Klipstein-Grobusch, Hutan Ashrafian, Nuria Casamitjana, Antoine Flahault, Anette Agardh, Astrid Berner-Rodoreda, Mario Raviglione, Günter Fröschl, Jolene Skordis-Worral, Leo Visser, Constance Schultsz, Antoni Plasència, Robyn Norton, Remko van Leeuwen
Publikováno v:
BMJ Global Health, Vol 4, Iss 5 (2019)
Global Health has not featured as prominently in the European Union (EU) research agenda in recent years as it did in the first decade of the new millennium, and participation of low-income and middle-income countries (LMICs) in EU health research ha
Externí odkaz:
https://doaj.org/article/fb795a5ef7ad40d09c6b1b4d1d88ce31
Autor:
Colin Bournez, Martijn Riool, Leonie de Boer, Robert A. Cordfunke, Leonie de Best, Remko van Leeuwen, Jan Wouter Drijfhout, Sebastian A. J. Zaat, Gerard J. P. van Westen
Publikováno v:
Antibiotics; Volume 12; Issue 4; Pages: 725
Antibiotics, 12(4):725
Antibiotics, 12(4):725. Multidisciplinary Digital Publishing Institute (MDPI)
Antibiotics, 12(4):725
Antibiotics, 12(4):725. Multidisciplinary Digital Publishing Institute (MDPI)
To combat infection by microorganisms host organisms possess a primary arsenal via the innate immune system. Among them are defense peptides with the ability to target a wide range of pathogenic organisms, including bacteria, viruses, parasites, and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bc8bc37eb251bc4d3bda010ce4400bf
https://hdl.handle.net/1887/3618249
https://hdl.handle.net/1887/3618249
Autor:
Antoni Plasència, Simone Villa, Ibrahim Abubakar, Astrid Berner-Rodoreda, Mario Carlo Raviglione, Günter Fröschl, Marianne A B van der Sande, Oriana Ramirez-Rubio, Claire Craig Gray, Frank Cobelens, Núria Casamitjana, Remko van Leeuwen, Flemming Konradsen, David Gisselsson Nord, Till Bärnighausen, Clarissa Prazeres da Costa
Publikováno v:
The Lancet, 397(10290), 2145-2147. Elsevier Limited
Autor:
Frejus Jeannot Zinsou, David Diemert, Jeffrey M. Bethony, Simon P. Jochems, Martin P. Grobusch, Yabo Josiane Honkpehedji, Sophie De Vries, Maria Elena Bottazzi, Peter J. Hotez, Remko van Leeuwen, Peter G. Kremsner, Friederike Sonnet, Jean-Claude Dejon Agobe, Ayola A. Adegnika, Yoanne D. Mouwenda, Koen A. Stam, Lucja A. Labuda, Marguerite Massinga Loembe, Madeleine E. Betouke Ongwe, Maria Yazdanbakhsh
Publikováno v:
PLOS NEGLECTED TROPICAL DISEASES, 15(10). PUBLIC LIBRARY SCIENCE
PLoS neglected tropical diseases, 15(10):e0009732. Public Library of Science
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009732 (2021)
PLoS neglected tropical diseases, 15(10):e0009732. Public Library of Science
PLoS Neglected Tropical Diseases
PLoS Neglected Tropical Diseases, Vol 15, Iss 10, p e0009732 (2021)
Two hookworm vaccine candidates, Na-GST-1 and Na-APR-1, formulated with Glucopyranosyl Lipid A (GLA-AF) adjuvant, have been shown to be safe, well tolerated, and to induce antibody responses in a Phase 1 clinical trial (Clinicaltrials.gov NCT02126462
Autor:
Martin P. Grobusch, Frejus Jeannot Zinsou, Peter G. Kremsner, Remko van Leeuwen, David Diemert, Sophia G. de Vries, Eunice M Betouke Ongwe, Benjamin Mordmueller, Marjan Molemans, Odilon Nouatin, Susana Pinto de Jesus, Jean-Claude Dejon Agobe, Ayola A. Adegnika, Emmanuel B. Bache, Selidji T Agnandji, Yabo J Honkepehedji, Kafui G Vodonou, Rodrigue Bikangui, Prince G Manouana, Peter J. Hotez, Bertrand Lell, Aurore Bouyoukou Hounkpatin, Maria Yazdanbakhsh, Marguerite Massinga Loembe, Anne-Marie Nkoma Mouima, Jean Ronald Edoa, Carsten Koehler, Guangzhao Li, Yoanne D. Mouwenda, Vera Kühne, Maria Elena Bottazzi, Jeffrey M. Bethony
Publikováno v:
The Lancet Infectious Diseases
The Lancet Infectious Diseases, 21(2), 275-285. ELSEVIER SCI LTD
The Lancet Infectious Diseases, 21(2), 275-285. ELSEVIER SCI LTD
Background Hookworms cause substantial morbidity in children and women of reproductive age. The control strategy of mass drug administration is suboptimal, hence the need for a vaccine. Necator americanus aspartic protease-1 (Na-APR-1) and N american
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6eb55fd2ffad7c271f775a2b2d818cb0
https://hdl.handle.net/1887/3214678
https://hdl.handle.net/1887/3214678
Autor:
Marion Rietveld, Jan W. Drijfhout, Alwin E. Adriaans, Peter H. Nibbering, Kirsten J. M. Schimmel, Robert A. Cordfunke, Suzan Commandeur, Sarah Zwart, Abdoelwaheb El Ghalbzouri, Elisabeth M. Haisma, Anikó Göblyös, Bep Ravensbergen, Jan den Hartigh, Remko van Leeuwen
Publikováno v:
International Journal of Antimicrobial Agents, 54(5), 610-618. ELSEVIER
Skin bacterial colonization/infection is a frequent cause of morbidity in patients with chronic wounds and allergic/inflammatory skin diseases. This study aimed to develop a novel approach to eradicate meticillin-resistant Staphylococcus aureus (MRSA
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d1d989a7219782a5a850e344b063d61
http://hdl.handle.net/1887/122411
http://hdl.handle.net/1887/122411
Autor:
Bayode Romeo Adegbite, Jeannot Fréjus Zinsou, Ayola A. Adegnika, Peter J. Hotez, Maria Elena Botazzi, Dejon Agobe Jean Claude, Maria Yazdanbakhsh, Jean Ronald Edoa, Josiane Honpkehedji, Remko van Leeuwen, Sophie De Vries, Peter G. Kremsner, David Diemert, Martin P. Grobusch
Publikováno v:
BMJ Global Health. 4:A12.1-A12
BackgroundHuman hookworm infection is a major public health issue in tropical low and middle-income countries with severe consequences. To date, improvement of water supply, sanitation, and hygiene is the major contributor to disease control, and add
Autor:
Phuong L. Nguyen, Esteban Martínez, Cavan S. Reilly, Ashley T. Haase, Elzbieta Bakowska, Andrzej Horban, Robert L. Murphy, Baiba Berzins, Remko van Leeuwen, Steven M. Wolinsky, Timothy W. Schacker, José M. Gatell
Publikováno v:
Journal of infectious diseases, 186(8), 1092-1097. Oxford University Press
The Journal of Infectious Diseases, 186(8), 1092-1097. Oxford University Press
The Journal of Infectious Diseases, 186(8), 1092-1097. Oxford University Press
Effective highly active antiretroviral therapy (HAART) for human immunodeficiency virus type 1 is associated with virus suppression and immune reconstitution. However, in some patients, this reconstitution is partial or incomplete because CD4(+) cell