Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Remie A. Fujiwara"'
Autor:
Douglas S. Chapin, Sheryl A. McCarthy, Jeffrey L. Stock, Christopher J. Schmidt, Robert D. Williams, Christine A. Strick, Frank S. Menniti, Larry C. James, John D. McNeish, Remie A. Fujiwara, Judith A. Siuciak
Publikováno v:
Neuropharmacology. 51:374-385
PDE10A is a newly identified phosphodiesterase that is highly expressed by the medium spiny projection neurons of the striatum. In order to investigate the physiological role of PDE10A in the central nervous system, PDE10A knockout mice (PDE10A(-/-))
The activity of pramipexole in the mouse forced swim test is mediated by D2 rather than D3 receptors
Autor:
Judith A. Siuciak, Remie A. Fujiwara
Publikováno v:
Psychopharmacology. 175
Recent studies have reported antidepressant-like activities of the dopamine D2/D3 agonist pramipexole in the chronic mild stress model and in the forced swim test, suggesting that D3 receptor agonists may represent a new class of antidepressant drugs