Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Remi Jawando"'
Autor:
Ching He, Nancy Doyle, Erin Stevens, Padma K. Narayanan, Remi Jawando, Cen Xu, Nianyu Li, Madeline M. Fort, Kevin Salyers, Florence Poitout-Belissent, Riki Stevenson, Mai Phuong Nguyen, Katherine Sprugel, Vibha Jawa, Nancy E. Everds, Keith Bailey, Sam M Tran, Jacquelin Jolette
Publikováno v:
Toxicologic Pathology. 41:951-969
Cynomolgus monkeys dosed with a therapeutic monoclonal antibody (mAbY.1) at ≥50 mg/kg had unexpected acute thrombocytopenia (nadir ∼3,000 platelets/µl), sometimes with decreases in red cell mass. Increased activated macrophages, mitotic figures,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705a5085d5ece89e6d49152525d560d7
https://doi.org/10.1177/0192623312474727
https://doi.org/10.1177/0192623312474727
Autor:
Dan A. Rock, Wei-Jian Pan, Michael J. Santostefano, Hugo M. Vargas, James F. Reindel, Duc Tran, Madeline M. Fort, Kai O. Reynhardt, Jacqueline A. Kirchner, Padma K. Narayanan, Remi Jawando, William A. Rees, Nancy E. Everds, Peter J. Prince, Sean Lear, Kelly Hensley, Christine Vissinga
Publikováno v:
Toxicologic pathology. 40(6)
AMG X, a human neutralizing monoclonal antibody (mAb) against a soluble human protein, caused thrombocytopenia, platelet activation, reduced mean arterial pressure, and transient loss of consciousness in cynomolgus monkeys after first intravenous adm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48b455e0b072e4e10b74933b0f1af8bc
https://pubmed.ncbi.nlm.nih.gov/22552394
https://pubmed.ncbi.nlm.nih.gov/22552394