Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Remedios Nazareno"'
Publikováno v:
PLoS ONE, Vol 8, Iss 6, p e65362 (2013)
INTRODUCTION: Type 1 interferon (IFN)-inducible genes and their inducible products are upregulated in dermatomyositis muscle. Of these, IFN-stimulated gene 15 (ISG15) is one of the most upregulated, suggesting its possible involvement in the pathogen
Externí odkaz:
https://doaj.org/article/db7e3586319a4e77ba3c5cee3d82dfc0
Autor:
Mohammad Salajegheh, Theresa Lam, Remedios Nazareno, Steven A. Greenberg, Stephen J. Elledge, H. Benjamin Larman, Jack L. Pinkus, Anthony A. Amato, John F. Sauld, Hanno Steen, Sek Won Kong
Publikováno v:
Annals of Neurology. 73:408-418
Objective We previously identified a circulating autoantibody against a 43 kDa muscle autoantigen in sporadic inclusion body myositis (IBM) and demonstrated the feasibility of an IBM diagnostic blood test. Here, we sought to identify the molecular ta
Autor:
Mohammad Salajegheh, Remedios Nazareno, Anne P. Liao, Chris Morehouse, Ronald G. Jubin, Yihong Yao, Steven A. Greenberg, Bahija Jallal
Publikováno v:
Clinical Immunology. 136:130-138
To determine the potential consequences of plasmacytoid dendritic cell (pDC) accumulation in tissue sites observed in several autoimmune diseases, we measured type 1 interferon production from circulating human pDCs as a function of pDC concentration
Autor:
Jack L. Pinkus, Ronan J. Walsh, Anthony A. Amato, Brandon W. Higgs, Steven A. Greenberg, Mohammad Salajegheh, Bryan Krastins, Remedios Nazareno, Chris Morehouse, Sek Won Kong, David A. Sarracino, Yihong Yao, Bahija Jallal, Anne Liao, Kenneth C. Parker
Publikováno v:
Annals of Neurology. 67:53-63
Dermatomyositis (DM) is an autoimmune disease of unknown cause primarily affecting skeletal muscle and skin. The characteristic muscle pathology of DM is notable for capillary abnormalities and small, abnormal appearing muscle fibers around the perip
Autor:
Remedios Nazareno, Steven A. Greenberg, J. Paul Taylor, Jack L. Pinkus, Anthony A. Amato, Mohammad Salajegheh, Robert H. Baloh
Publikováno v:
Muscle & Nerve. 40:19-31
The nucleic acid binding protein TDP-43 was recently identified in normal myonuclei and in the sarcoplasm of inclusion body myositis (IBM) muscle. Here we found TDP-43 sarcoplasmic immunoreactivity in 23% of IBM myofibers, while other reported IBM bi
Publikováno v:
PLoS ONE
PLoS ONE, Vol 8, Iss 6, p e65362 (2013)
PLoS ONE, Vol 8, Iss 6, p e65362 (2013)
INTRODUCTION: Type 1 interferon (IFN)-inducible genes and their inducible products are upregulated in dermatomyositis muscle. Of these, IFN-stimulated gene 15 (ISG15) is one of the most upregulated, suggesting its possible involvement in the pathogen
Autor:
H Benjamin, Larman, Mohammad, Salajegheh, Remedios, Nazareno, Theresa, Lam, John, Sauld, Hanno, Steen, Sek Won, Kong, Jack L, Pinkus, Anthony A, Amato, Stephen J, Elledge, Steven A, Greenberg
Publikováno v:
Annals of neurology. 73(3)
We previously identified a circulating autoantibody against a 43 kDa muscle autoantigen in sporadic inclusion body myositis (IBM) and demonstrated the feasibility of an IBM diagnostic blood test. Here, we sought to identify the molecular target of th
Autor:
Kenneth C. Parker, Remedios Nazareno, Jack L. Pinkus, Steven A. Greenberg, Anthony A. Amato, Mohammad Salajegheh
Publikováno v:
Musclenerve. 40(4)
Sarcoplasmic accumulation of phosphorylated-tau has been widely stated to occur in and contribute to the pathogenesis of muscle disease in inclusion body myositis. Twenty inflammatory myopathy and 10 normal muscle samples along with a range of other
Autor:
Mohammad, Salajegheh, Jack L, Pinkus, J Paul, Taylor, Anthony A, Amato, Remedios, Nazareno, Robert H, Baloh, Steven A, Greenberg
Publikováno v:
Musclenerve. 40(1)
The nucleic acid binding protein TDP-43 was recently identified in normal myonuclei and in the sarcoplasm of inclusion body myositis (IBM) muscle. Here we found TDP-43 sarcoplasmic immunoreactivity in 23% of IBM myofibers, while other reported IBM bi
Autor:
Remedios Nazareno, N R Jayagopala Reddy, Ana C. Anderson, Vijay K. Kuchroo, Lindsay B. Nicholson, Raymond A. Sobel
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 173(2)
We have previously shown that naive SJL (H-2s) mice, which are highly susceptible to myelin proteolipid protein (PLP)-induced experimental autoimmune encephalomyelitis (EAE), have a very high frequency (1/20,000 CD4 T cells) of PLP139–151-reactive