Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Remdesivir (GS-5734)"'
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Remdesivir is widely used for the management of COVID-19 and several studies have reported bradycardia as a potential side effect associated with this agent. The aim of the present study was to evaluate the incidence rate, severity, and p
Externí odkaz:
https://doaj.org/article/14e9ed6d31124e819473dd1f7d7c2022
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Aim: Kidney impairment is observed in patients with COVID-19. The effect of anti-COVID-19 agent remdesivir on kidneys is currently unknown. We aimed to determine the effect of remdesivir on renal fibrosis and its downstream mechanisms.Methods: Remdes
Externí odkaz:
https://doaj.org/article/053e53f3f1cb41c4a8ce80decb6389d1
Autor:
Yi-Hao Chan, Barnaby E. Young, Siew-Wai Fong, Ying Ding, Yun Shan Goh, Rhonda Sin-Ling Chee, Seow-Yen Tan, Shirin Kalimuddin, Paul A. Tambyah, Yee-Sin Leo, Lisa F. P. Ng, David Chien Lye, Laurent Renia
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
A significant proportion of COVID-19 patients will progress to critical illness requiring invasive mechanical ventilation. This accentuates the need for a therapy that can reduce the severity of COVID-19. Clinical trials have shown the effectiveness
Externí odkaz:
https://doaj.org/article/8a02a39764fe485fb57a9944f6c13c6a
Autor:
Vikas Bansal, Kiran S. Mahapure, Abhishek Bhurwal, Ishita Gupta, Sahar Hassanain, Janaki Makadia, Nimisha Madas, Paige Armaly, Romil Singh, Ishita Mehra, John C. O'Horo, Rahul Kashyap
Publikováno v:
Frontiers in Medicine, Vol 7 (2021)
Importance/Background: During current public health emergency of COVID-19 pandemic, repurposing of existing antiviral drugs may be an efficient strategy since there is no proven effective treatment. Published literature shows Remdesivir has broad-spe
Externí odkaz:
https://doaj.org/article/53368241987147dbb24ea7354026fa65
Autor:
Wei Ye, Min Yao, Yangchao Dong, Chuantao Ye, Dan Wang, He Liu, Hongwei Ma, Hui Zhang, Libin Qi, Yuewu Yang, Yuan Wang, Liang Zhang, Linfeng Cheng, Xin Lv, Zhikai Xu, Yingfeng Lei, Fanglin Zhang
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Externí odkaz:
https://doaj.org/article/1c01f4ecc76647d6953c0e100572eb16
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Remdesivir (RDV, GS-5734), a broad-spectrum antiviral drug in the class of nucleotide analogs, has been particularly tailored for treatment of coronavirus infections. However, to which extent RDV is able to modify various types of membrane ion curren
Externí odkaz:
https://doaj.org/article/00544052592b4aeeaaa38edff938ce2c
Autor:
Wei Ye, Min Yao, Yangchao Dong, Chuantao Ye, Dan Wang, He Liu, Hongwei Ma, Hui Zhang, Libin Qi, Yuewu Yang, Yuan Wang, Liang Zhang, Linfeng Cheng, Xin Lv, Zhikai Xu, Yingfeng Lei, Fanglin Zhang
Publikováno v:
Frontiers in Microbiology, Vol 11 (2020)
Human enteroviruses are responsible for diverse diseases, from mild respiratory symptoms to fatal neurological complications. Currently, no registered antivirals have been approved for clinical therapy. Thus, a therapeutic agent for the enterovirus-r
Externí odkaz:
https://doaj.org/article/163e2dead6f24f6d9969a3aef25e9bf5
Akademický článek
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Akademický článek
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Publikováno v:
Polycyclic Aromatic Compounds
The novel coronavirus disease 2019 (COVID-19) emerged in Wuhan, China, and has spread rapidly to nearly every part of the world. Unfortunately, no drug or vaccine has been accepted for the treatment of this pandemic. Researchers have established the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6914f4469f6ce698f18347a517b3456
http://europepmc.org/articles/PMC7267043
http://europepmc.org/articles/PMC7267043