Výsledky vyhledávání - "Remco J, Knol"

Radiosynoviorthesis: almost seventy years of experience but still somewhat fameless

Autor: Friso M. van der ZANT, Remco J. KNOL, Wouter A. BROOS

Publikováno v: The quarterly journal of nuclear medicine and molecular imaging : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR), [and] Section of the Society of.... 66(4)

Radiosynoviorthesis (RSO) or radiation synovectomy has been practiced for more than half a century, but in many parts of the world, it is still relatively unknown and not used to its full potential in the standard care for chronic, persistent or recu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2a1b72e1c99088d9894c7f2a9e82dcc0
https://pubmed.ncbi.nlm.nih.gov/35708601

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Design, synthesis, radiolabeling, and in vitro and in vivo evaluation of bridgehead iodinated analogues of N-{2-[4-(2-methoxyphenyl)piperazin-1-yl]ethyl}-N-(pyridin-2-yl)cyclohexanecarboxamide (WAY-100635) as potential SPECT ligands for the 5-HT1A receptor

Autor: Rana, Al Hussainy, Joost, Verbeek, Dion, van der Born, Anton H, Braker, Josée E, Leysen, Remco J, Knol, Jan, Booij, J Koos D M, Herscheid

Publikováno v: Journal of medicinal chemistry. 54(10)

Here we describe the design, synthesis, and pharmacological profile of 5-HT(1A) receptor ligands related to 1 (WAY-100635). The cyclohexyl moiety in 1 and its O-desmethylated analogue 3 were replaced by the bridgehead iodinated bridge-fused rings: ad

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::db4a5dd222bf7a0e9f5e47fa9a4b6944
https://pubmed.ncbi.nlm.nih.gov/21520940

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