Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Remai Parker"'
Autor:
Ping Siu Kee, Simran D. S. Maggo, Martin A. Kennedy, Murray L. Barclay, Allison L. Miller, Klaus Lehnert, Maurice A. Curtis, Richard L. M. Faull, Remai Parker, Paul K. L. Chin
Publikováno v:
Frontiers in Genetics, Vol 13 (2022)
Omeprazole is extensively used to manage gastroesophageal reflux disease (GERD). It is primarily metabolized by CYP2C19. The CYP2C19*17 (rs12248560) allele and the recently described CYP2C:TG haplotype (rs11188059 and rs2860840) are associated with i
Externí odkaz:
https://doaj.org/article/1a6d85326f064630b4559320e165eea4
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 14 (2021)
Gene expression studies of human post-mortem brain tissue are useful for understanding the pathogenesis of neurodegenerative disease. These studies rely on the assumption that RNA quality is consistent between disease and neurologically normal cases;
Externí odkaz:
https://doaj.org/article/bc61532a296142d095955929627b6878
Autor:
Blake Highet, James A. Wiseman, Hannah Mein, Remai Parker, Brigid Ryan, Clinton P. Turner, Yu Jing, Malvindar K. Singh-Bains, Ping Liu, Mike Dragunow, Richard L.M. Faull, Helen C. Murray, Maurice A. Curtis
Publikováno v:
Journal of Alzheimer's Disease. 92:371-390
Background: Alzheimer’s disease (AD) is the most common form of dementia and is characterized by a substantial reduction of neuroplasticity. Our previous work demonstrated that neurons involved in memory function may lose plasticity because of decr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::21a9122f891d15d94caec53061fb4178
https://doi.org/10.3233/jad-220986
https://doi.org/10.3233/jad-220986
Autor:
E E Langton, David O. Hutchinson, Anja H. Schiemann, Richard Roxburgh, Kathryn M. Stowell, Neil Pollock, Andrew R. Bjorksten, Remai Parker, R. L. Gillies, Terasa Bulger
Publikováno v:
Journal of Neuromuscular Diseases
Background Central core disease and malignant hyperthermia are human disorders of skeletal muscle resulting from aberrant Ca2+ handling. Most malignant hyperthermia and central core disease cases are associated with amino acid changes in the type 1 r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::704b6b02fef6872038068ba0b9e7f90d
https://doi.org/10.3233/jnd-170210
https://doi.org/10.3233/jnd-170210
Publikováno v:
Anesthesia & Analgesia. 118:375-380
Background Malignant hyperthermia (MH) is a potentially lethal pharmacogenetic disorder. More than 300 variants in the ryanodine receptor 1 (RYR1) have been associated with MH; however, only 31 have been identified as causative. To confirm a mutation
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b14a830146713c3b5a4d378322f6ac2
https://doi.org/10.1213/ane.0b013e3182a273ea
https://doi.org/10.1213/ane.0b013e3182a273ea