DNA toxicity of cocaine hydrochloride and cocaine freebase by means of DNA image analysis on Tetrahymena pyriformis

Autor: Stefanidou, M. Chatziioannou, A. Livaditou, A. Rellaki, A. Alevisopoulos, G. Spiliopoulou, H. Koutselinis, A.

An assay for computerized scoring of the DNA content of the protozoan Tetrahymena pyriformis has been used for the detection of toxic responses to cocaine, since DNA is responsible for the replication of the genetic material and also reflects closely

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______2127::9be5675a82b98e4f50e0b2c86c740054
https://pergamos.lib.uoa.gr/uoa/dl/object/uoadl:3022955

Genotoxicity, oxidative stress, and inflammatory response induced by crack-cocaine: relevance to carcinogenesis.

Autor: Malacarne IT; Department of Biosciences, Federal University of São Paulo, UNIFESP, Rua Silva Jardim, 136, Room 332, Vila Mathias, Santos, SP, 11050-020, Brazil., De Souza DV; Department of Biosciences, Federal University of São Paulo, UNIFESP, Rua Silva Jardim, 136, Room 332, Vila Mathias, Santos, SP, 11050-020, Brazil., Rosario BDA; Department of Biosciences, Federal University of São Paulo, UNIFESP, Rua Silva Jardim, 136, Room 332, Vila Mathias, Santos, SP, 11050-020, Brazil., Viana MB; Department of Biosciences, Federal University of São Paulo, UNIFESP, Rua Silva Jardim, 136, Room 332, Vila Mathias, Santos, SP, 11050-020, Brazil., Pereira CDS; Department of Marine Sciences, Federal University of São Paulo, UNIFESP, Santos, SP, Brazil., Estadella D; Department of Biosciences, Federal University of São Paulo, UNIFESP, Rua Silva Jardim, 136, Room 332, Vila Mathias, Santos, SP, 11050-020, Brazil., Dos Santos JN; Department of Oral Diagnosis and Therapeutics, Faculty of Dentistry, Federal University of Bahia, Salvador, BA, Brazil., Ribeiro DA; Department of Biosciences, Federal University of São Paulo, UNIFESP, Rua Silva Jardim, 136, Room 332, Vila Mathias, Santos, SP, 11050-020, Brazil. daribeiro@unifesp.br.

Publikováno v: Environmental science and pollution research international [Environ Sci Pollut Res Int] 2021 Mar; Vol. 28 (12), pp. 14285-14292. Date of Electronic Publication: 2021 Feb 03.