Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Rekha Raghunathan"'
Publikováno v:
MethodsX, Vol 6, Iss , Pp 2329-2347 (2019)
We describe a protocol for glycomic and proteomic profiling that uses serial enzyme digestions from the surface of fresh frozen or fixed tissue slides. The abundances of the extracted glycans and peptides are determined using liquid chromatography-ma
Externí odkaz:
https://doaj.org/article/146f2c9d7d9848e1b31ee5affd3b9e96
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 16, p 9299 (2022)
Neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) are both characterized by pathogenic protein aggregates that correlate with the progressive degeneration of neurons and the loss of behavioral funct
Externí odkaz:
https://doaj.org/article/7c1d9675467a443fb875b8a977dd2903
Autor:
Yang Yang, Jaeil Ahn, Rekha Raghunathan, Bhaskar V. Kallakury, Bruce Davidson, Zuzana Brnakova Kennedy, Joseph Zaia, Radoslav Goldman
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Sulfation of heparan sulfate proteoglycans (HSPG) regulates signaling of growth factor receptors via specific interactions with the sulfate groups. 6-O-Sulfation of HSPG is an impactful modification regulated by the activities of dedicated extracellu
Externí odkaz:
https://doaj.org/article/92fd7849509b421b86479f0e80d7c514
Autor:
Sam Thiagalingam, Hamid M. Abdolmaleky, Björn M. Reinhard, Adam C. Gower, Yuriy Alekseyev, Rekha Raghunathan, Panagiotis Papageorgis, Sait Ozturk, Chen Khuan Wong, Arthur W. Lambert
Knockdown of POSTN and ITGB3 in SUM159 cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01f07ef1d56aee1886fc9270c5145ac1
https://doi.org/10.1158/1541-7786.22511034
https://doi.org/10.1158/1541-7786.22511034
Autor:
Sam Thiagalingam, Hamid M. Abdolmaleky, Björn M. Reinhard, Adam C. Gower, Yuriy Alekseyev, Rekha Raghunathan, Panagiotis Papageorgis, Sait Ozturk, Chen Khuan Wong, Arthur W. Lambert
This file contains figure legends for the supplementary data figures.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31d269d8932301bdaf2c70fdb9693ced
https://doi.org/10.1158/1541-7786.22511010.v1
https://doi.org/10.1158/1541-7786.22511010.v1
Publikováno v:
Anal Bioanal Chem
Extracellular matrix (ECM) proteins, collectively known as the matrisome, include collagens, glycoproteins, and proteoglycans. Alterations in the matrisome have been implicated in the neurodegenerative pathologies including Parkinson’s disease (PD)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b0f97797ab6c46ed38f249083e668b2d
https://doi.org/10.1007/s00216-022-03929-4
https://doi.org/10.1007/s00216-022-03929-4
Publikováno v:
MethodsX
MethodsX, Vol 6, Iss, Pp 2329-2347 (2019)
MethodsX, Vol 6, Iss, Pp 2329-2347 (2019)
Graphical abstract
We describe a protocol for glycomic and proteomic profiling that uses serial enzyme digestions from the surface of fresh frozen or fixed tissue slides. The abundances of the extracted glycans and peptides are determined using
We describe a protocol for glycomic and proteomic profiling that uses serial enzyme digestions from the surface of fresh frozen or fixed tissue slides. The abundances of the extracted glycans and peptides are determined using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9454c4ed235907e90bc006a29a88dcc4
http://europepmc.org/articles/PMC6807300
http://europepmc.org/articles/PMC6807300
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific Reports
Scientific Reports
Previous studies on Parkinson’s disease mechanisms have shown dysregulated extracellular transport of α-synuclein and growth factors in the extracellular space. In the human brain these consist of perineuronal nets, interstitial matrices, and base
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a5c173826668b11a46d5a009ab6c8318
https://doi.org/10.1038/s41598-020-69480-3
https://doi.org/10.1038/s41598-020-69480-3
Autor:
Yang Yang, Jaeil Ahn, Rekha Raghunathan, Bhaskar V. Kallakury, Bruce Davidson, Zuzana Brnakova Kennedy, Joseph Zaia, Radoslav Goldman
Publikováno v:
Frontiers in Oncology, Vol 10 (2021)
Frontiers in Oncology
Frontiers in Oncology
Sulfation of heparan sulfate proteoglycans (HSPG) regulates signaling of growth factor receptors via specific interactions with the sulfate groups. 6-O-Sulfation of HSPG is an impactful modification regulated by the activities of dedicated extracellu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3175aa92726a1adba32d6c1273d11d20
https://pubmed.ncbi.nlm.nih.gov/33585200
https://pubmed.ncbi.nlm.nih.gov/33585200
Autor:
Patty Sheehan, Laura D. Heckman, Li Chin Wong, Sid Kamalakaran, Zhaohui Yang, Hsuan-Ni Lin, Swetha Garimalla, Dominik Biezonski, Jeremiah Hendricks, Rekha Raghunathan, Zoe Zhao, Priyam Raut, Jason Politi, Yong Dai, Asa Abeliovich, Franz Hefti
Publikováno v:
Molecular Genetics and Metabolism. 135:S112
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13dd9359c0cbb75b88a4df5458c272fe
https://doi.org/10.1016/j.ymgme.2021.11.296
https://doi.org/10.1016/j.ymgme.2021.11.296