Zobrazeno 1 - 10
of 36
pro vyhledávání: '"Rekha Gyanchandani"'
Autor:
Nicholas G. Smith, Rekha Gyanchandani, Osama S. Shah, Grzegorz T. Gurda, Peter C. Lucas, Ryan J. Hartmaier, Adam M. Brufsky, Shannon Puhalla, Amir Bahreini, Karthik Kota, Abigail I. Wald, Yuri E. Nikiforov, Marina N. Nikiforova, Steffi Oesterreich, Adrian V. Lee
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-11 (2019)
Abstract Background Breast cancer is the most common invasive cancer among women worldwide. Next-generation sequencing (NGS) has revolutionized the study of cancer across research labs around the globe; however, genomic testing in clinical settings r
Externí odkaz:
https://doaj.org/article/bb493478f40a4015bc69fa0c67422ae2
Autor:
Daniel M Spagnolo, Rekha Gyanchandani, Yousef Al-Kofahi, Andrew M Stern, Timothy R Lezon, Albert Gough, Dan E Meyer, Fiona Ginty, Brion Sarachan, Jeffrey Fine, Adrian V Lee, D Lansing Taylor, S Chakra Chennubhotla
Publikováno v:
Journal of Pathology Informatics, Vol 7, Iss 1, Pp 47-47 (2016)
Background: Measures of spatial intratumor heterogeneity are potentially important diagnostic biomarkers for cancer progression, proliferation, and response to therapy. Spatial relationships among cells including cancer and stromal cells in the tumor
Externí odkaz:
https://doaj.org/article/0133c569b3f04299ad5b8fe46e6286f6
PDF file - 132K, Differentially expressed genes between resistant/bevacizumab tumors compared to parental/bevacizumab tumors.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::396f0375a360d4dd8dd26a69d03b2697
https://doi.org/10.1158/1541-7786.22509913.v1
https://doi.org/10.1158/1541-7786.22509913.v1
Autor:
Steffi Oesterreich, Adrian V. Lee, Shannon L. Puhalla, Andrew M. Stern, Tadeu F. Ambros, Adam M. Brufsky, Marina N. Nikiforova, Nancy E. Davidson, Jose Pablo Leone, Aju Mathew, Kurt R. Weiss, Brenda F. Kurland, Ronald L. Hamilton, Aaron Berg, Humberto E. Trejo Bittar, Amruth R. Jonnalagadda, Rebecca J. Watters, Ryan J. Hartmaier, Peter C. Lucas, Rekha Gyanchandani, Amir Bahreini, Peilu Wang
Supplementary Figure S1A. Pre-amplification preserves mutant allele frequency and maintains sensitivity of ESR1-D538G mutation detection by ddPCR. Supplementary Figure S1B. Pre-amplification preserves mutant allele frequency and maintains sensitivity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::874ed3e0b6ca905da80f77a7a103a569
https://doi.org/10.1158/1078-0432.22457271
https://doi.org/10.1158/1078-0432.22457271
Autor:
Adrian V. Lee, David J. Dabbs, Rohit Bhargava, Nancy E. Davidson, Steffi Oesterreich, Whitney Crosson, Michael Fastuca, Adam Brufsky, Daniel P. Normolle, Kristine Cooper, Hui-Min Lin, Yan Lin, Rekha Gyanchandani
Purpose: To examine the effect of intratumor heterogeneity (ITH) on detection of genes within gene expression panels (GEPs) and the subsequent ability to predict prognostic risk.Experimental Design: Multiplexed barcoded RNA analysis was used to measu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a1d7ce3ab1903310b809bb8d8d93c04b
https://doi.org/10.1158/1078-0432.c.6525107.v1
https://doi.org/10.1158/1078-0432.c.6525107.v1
Autor:
Adrian V. Lee, David J. Dabbs, Rohit Bhargava, Nancy E. Davidson, Steffi Oesterreich, Whitney Crosson, Michael Fastuca, Adam Brufsky, Daniel P. Normolle, Kristine Cooper, Hui-Min Lin, Yan Lin, Rekha Gyanchandani
Immunohistochemical expression levels for ER, PR, HER2 and Ki67
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039ecb074897007642a721b087a40f0b
https://doi.org/10.1158/1078-0432.22462451
https://doi.org/10.1158/1078-0432.22462451
Autor:
Adrian V. Lee, David J. Dabbs, Rohit Bhargava, Nancy E. Davidson, Steffi Oesterreich, Whitney Crosson, Michael Fastuca, Adam Brufsky, Daniel P. Normolle, Kristine Cooper, Hui-Min Lin, Yan Lin, Rekha Gyanchandani
Figures S1, S2, S3, S4, S5, and S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac9615309b04b148596a3f995c57c6ed
https://doi.org/10.1158/1078-0432.22462457
https://doi.org/10.1158/1078-0432.22462457
Autor:
Steffi Oesterreich, Adrian V. Lee, Shannon L. Puhalla, Andrew M. Stern, Tadeu F. Ambros, Adam M. Brufsky, Marina N. Nikiforova, Nancy E. Davidson, Jose Pablo Leone, Aju Mathew, Kurt R. Weiss, Brenda F. Kurland, Ronald L. Hamilton, Aaron Berg, Humberto E. Trejo Bittar, Amruth R. Jonnalagadda, Rebecca J. Watters, Ryan J. Hartmaier, Peter C. Lucas, Rekha Gyanchandani, Amir Bahreini, Peilu Wang
Table S1. Sequence of targeted amplification primers. Table S2. Sequence of ddPCR primer and probes. Table S3. Cellularity and location of bone metastases.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1310c8ff3b02821d6e1216a97abb59d4
https://doi.org/10.1158/1078-0432.22457268.v1
https://doi.org/10.1158/1078-0432.22457268.v1
Autor:
Steffi Oesterreich, Adrian V. Lee, Shannon L. Puhalla, Andrew M. Stern, Tadeu F. Ambros, Adam M. Brufsky, Marina N. Nikiforova, Nancy E. Davidson, Jose Pablo Leone, Aju Mathew, Kurt R. Weiss, Brenda F. Kurland, Ronald L. Hamilton, Aaron Berg, Humberto E. Trejo Bittar, Amruth R. Jonnalagadda, Rebecca J. Watters, Ryan J. Hartmaier, Peter C. Lucas, Rekha Gyanchandani, Amir Bahreini, Peilu Wang
Purpose: Given the clinical relevance of ESR1 mutations as potential drivers of resistance to endocrine therapy, this study used sensitive detection methods to determine the frequency of ESR1 mutations in primary and metastatic breast cancer, and in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1ea50a5bb947e85250e708764f893c75
https://doi.org/10.1158/1078-0432.c.6523548
https://doi.org/10.1158/1078-0432.c.6523548
Autor:
Peter C. Lucas, Shannon Puhalla, Steffi Oesterreich, Abigail I. Wald, Marina N. Nikiforova, Rekha Gyanchandani, Amir Bahreini, Grzegorz T. Gurda, Karthik Kota, Nicholas G. Smith, Ryan J. Hartmaier, Adrian V. Lee, Osama Shiraz Shah, Yuri E. Nikiforov, Adam Brufsky
Publikováno v:
Breast Cancer Research, Vol 21, Iss 1, Pp 1-11 (2019)
Breast Cancer Research : BCR
Breast Cancer Research : BCR
Background Breast cancer is the most common invasive cancer among women worldwide. Next-generation sequencing (NGS) has revolutionized the study of cancer across research labs around the globe; however, genomic testing in clinical settings remains li