Zobrazeno 1 - 10
of 6 338
pro vyhledávání: '"Reis-Filho"'
Autor:
Zimmermann, Johannes, Wiktorek, Dariusz, Meusburger, Thomas, Monge-Dalmau, Miquel, Fabregat, Antonio, Jarasch, Alexander, Schmidt, Günter, Reis-Filho, Jorge S., Simpson, T. Ian
As the number of scientific publications and preprints is growing exponentially, several attempts have been made to navigate this complex and increasingly detailed landscape. These have almost exclusively taken unsupervised approaches that fail to in
Externí odkaz:
http://arxiv.org/abs/2408.03339
Autor:
Chiara Maria Lavinia Loeffler, Omar S. M. El Nahhas, Hannah Sophie Muti, Zunamys I. Carrero, Tobias Seibel, Marko van Treeck, Didem Cifci, Marco Gustav, Kevin Bretz, Nadine T. Gaisa, Kjong-Van Lehmann, Alexandra Leary, Pier Selenica, Jorge S. Reis-Filho, Nadina Ortiz-Bruechle, Jakob Nikolas Kather
Publikováno v:
BMC Biology, Vol 22, Iss 1, Pp 1-14 (2024)
Abstract Background Homologous recombination deficiency (HRD) is recognized as a pan-cancer predictive biomarker that potentially indicates who could benefit from treatment with PARP inhibitors (PARPi). Despite its clinical significance, HRD testing
Externí odkaz:
https://doaj.org/article/003303862b20434e84941368c6c014a7
Autor:
Kurt Schmid, Friedrich Wolfgang Keppeler, Fabio Renan Miranda da Silva, Jhully Helen da Silva Santos, Simone Franceschini, Jakob Brodersen, Tommaso Russo, Euan Harvey, José Amorim Reis-Filho, Tommaso Giarrizzo
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract The increase in the construction of mega dams in tropical basins is considered a threat to freshwater fish diversity. Although difficult to detect in conventional monitoring programs, rheophilic species and those reliant on shallow habitats
Externí odkaz:
https://doaj.org/article/89af0a8ed8ce4ec585e781eb31d70508
Autor:
Manisha Jalan, Aman Sharma, Xin Pei, Nils Weinhold, Erika S. Buechelmaier, Yingjie Zhu, Sana Ahmed-Seghir, Abhirami Ratnakumar, Melody Di Bona, Niamh McDermott, Joan Gomez-Aguilar, Kyrie S. Anderson, Charlotte K. Y. Ng, Pier Selenica, Samuel F. Bakhoum, Jorge S. Reis-Filho, Nadeem Riaz, Simon N. Powell
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-17 (2024)
Abstract Collisions of the transcription and replication machineries on the same DNA strand can pose a significant threat to genomic stability. These collisions occur in part due to the formation of RNA-DNA hybrids termed R-loops, in which a newly tr
Externí odkaz:
https://doaj.org/article/7cd61270c6534754a1bbd7203bce046c
Autor:
Yingjie Zhu, Xin Pei, Ardijana Novaj, Jeremy Setton, Daniel Bronder, Fatemeh Derakhshan, Pier Selenica, Niamh McDermott, Mehmet Orman, Sarina Plum, Shyamal Subramanyan, Sara H. Braverman, Biko McMillan, Sonali Sinha, Jennifer Ma, Andrea Gazzo, Atif Khan, Samuel Bakhoum, Simon N. Powell, Jorge S. Reis-Filho, Nadeem Riaz
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-17 (2024)
Abstract Background Pathogenic BRCA1 or BRCA2 germline mutations contribute to hereditary breast, ovarian, prostate, and pancreatic cancer. Paradoxically, bi-allelic inactivation of BRCA1 or BRCA2 (bBRCA1/2) is embryonically lethal and decreases cell
Externí odkaz:
https://doaj.org/article/a99e307f304a411b854e096a6e780f20
Autor:
Nahhas, Omar S. M. El, Loeffler, Chiara M. L., Carrero, Zunamys I., van Treeck, Marko, Kolbinger, Fiona R., Hewitt, Katherine J., Muti, Hannah S., Graziani, Mara, Zeng, Qinghe, Calderaro, Julien, Ortiz-Brüchle, Nadina, Yuan, Tanwei, Hoffmeister, Michael, Brenner, Hermann, Brobeil, Alexander, Reis-Filho, Jorge S., Kather, Jakob Nikolas
Deep Learning (DL) can predict biomarkers from cancer histopathology. Several clinically approved applications use this technology. Most approaches, however, predict categorical labels, whereas biomarkers are often continuous measurements. We hypothe
Externí odkaz:
http://arxiv.org/abs/2304.05153
Autor:
Steffi Oesterreich, Leigh Pate, Adrian V. Lee, Fangyuan Chen, Rachel C. Jankowitz, Rita Mukhtar, Otto Metzger, Matthew J. Sikora, Christopher I. Li, Christos Sotiriou, Osama S. Shah, Thijs Koorman, Gary Ulaner, Jorge S. Reis-Filho, Nancy M. Davidson, Karen Van Baelen, Laurie Hutcheson, Siobhan Freeney, Flora Migyanka, Claire Turner, Patrick Derksen, Todd Bear, Christine Desmedt
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-7 (2024)
Abstract There is growing awareness of the unique etiology, biology, and clinical presentation of invasive lobular breast cancer (ILC), but additional research is needed to ensure translation of findings into management and treatment guidelines. We c
Externí odkaz:
https://doaj.org/article/674206de519c4c9a91765a34839d5098
Publikováno v:
Rumores, Vol 18, Iss 35 (2024)
Propomos uma comparação entre o documentário Fireball: Mitos, cometas e meteoros (Fireball: Visitors from Darker Worlds, 2020), de Werner Herzog e Clive Oppenheimer, e o conto A cor que caiu do espaço (The Color Out of Space, 1927), de H. P. Love
Externí odkaz:
https://doaj.org/article/7e9935a53b3c4fd18fb228b4fea5f18f
Autor:
Raí Emanuel da Silva, Nathanael dos Santos Alves, Cynthia Karolina Rodrigues do Nascimento, Raylane Meneses Marques dos Santos, Wellerson Lucas de Pinho Barreto, Jadiel Silva Reis Filho, Victor Brito Dantas Martins, Erika Cecília Vallim Severino, Marcelo Costa Araújo, Miguel Araújo Rios Neto, Aline Dias Paiva, Kennio Ferreira-Paim, Fernanda Machado Fonseca
Publikováno v:
Bioscience Journal, Vol 40, Pp e40040-e40040 (2024)
This study aimed to identify and evaluate the antimicrobial susceptibility profile of extended-spectrum β-lactamase (ESBL)-producing Enterobacterales isolated from blood cultures of patients with suspected sepsis. This retrospective cross-sectional
Externí odkaz:
https://doaj.org/article/1cfe8e62e0a341a08922405b83f6205c
Autor:
Ivan José dos Reis Filho, Jamille de Campos Coleti, Ricardo Marcondes Marcacini, Solange Oliveira Rezende
Publikováno v:
Data in Brief, Vol 55, Iss , Pp 110545- (2024)
This dataset involves a collection of soybean market news through web scraping from a Brazilian website. The news articles gathered span from January 2015 to June 2023 and have undergone a labeling process to categorize them as relevant or non-releva
Externí odkaz:
https://doaj.org/article/eb3724434409498a875abb2fc2f436e7