The miR-17-92 cluster counteracts quiescence and chemoresistance in a distinct subpopulation of pancreatic cancer stem cells.

Autor: Cioffi M; Stem Cells & Cancer Group, CNIO, Madrid, Spain., Trabulo SM; Stem Cells & Cancer Group, CNIO, Madrid, Spain., Sanchez-Ripoll Y; Stem Cells & Cancer Group, CNIO, Madrid, Spain., Miranda-Lorenzo I; Stem Cells & Cancer Group, CNIO, Madrid, Spain., Lonardo E; Stem Cells & Cancer Group, CNIO, Madrid, Spain., Dorado J; Stem Cells & Cancer Group, CNIO, Madrid, Spain., Reis Vieira C; Stem Cells & Cancer Group, CNIO, Madrid, Spain Viral Vector Unit, Spanish National Cardiovascular Research Centre (CNIC), Madrid, Spain., Ramirez JC; Viral Vector Unit, Spanish National Cardiovascular Research Centre (CNIC), Madrid, Spain., Hidalgo M; Gastrointestinal Cancer Clinical Research Unit, Spanish National Cancer Research Centre (CNIO), Madrid, Spain., Aicher A; Stem Cells & Cancer Group, CNIO, Madrid, Spain., Hahn S; Department of Molecular Gastrointestinal Oncology, Ruhr-University Bochum, D-44801 Bochum, Germany., Sainz B Jr; Stem Cells & Cancer Group, CNIO, Madrid, Spain., Heeschen C; Stem Cells & Cancer Group, CNIO, Madrid, Spain Barts Cancer Institute, Centre for Stem Cells in Cancer & Ageing, Queen Mary University of London, London, UK.

Publikováno v: Gut [Gut] 2015 Dec; Vol. 64 (12), pp. 1936-48. Date of Electronic Publication: 2015 Apr 17.