Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Reint K, Jellema"'
Autor:
Floris Groenendaal, Wes Onland, Wessel Ganzevoort, Ewoud Schuit, Rene F. Kornelisse, Salwan Al-Nasiry, Mette van de Meent, Dianne G. Kleuskens, Sanne J. Gordijn, Elisabeth M. W. Kooi, Bas B. van Rijn, Johannes J. Duvekot, Reint K. Jellema, H. Marieke Knol, Gwendolyn T. R. Manten, Susanne M. Mulder-de Tollenaer, Jan B. Derks, Mireille N. Bekker, A. Titia Lely, Judith Kooiman
Publikováno v:
BMJ Open, Vol 13, Iss 3 (2023)
Introduction Early-onset fetal growth restriction (FGR) requires timely, often preterm, delivery to prevent fetal hypoxia causing stillbirth or neurologic impairment. Antenatal corticosteroids (CCS) administration reduces neonatal morbidity and morta
Externí odkaz:
https://doaj.org/article/947d069066f54a8ba600e15caf39f028
Autor:
Hyun Young Park, Valéry L. E. van Bruggen, Carine J. Peutz-Kootstra, Daan R. M. G. Ophelders, Reint K. Jellema, Chris P. M. Reutelingsperger, Bart P. F. Rutten, Tim G. A. M. Wolfs
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 6, p 5929 (2023)
Perinatal brain injury following hypoxia-ischemia (HI) is characterized by high mortality rates and long-term disabilities. Previously, we demonstrated that depletion of Annexin A1, an essential mediator in BBB integrity, was associated with a tempor
Externí odkaz:
https://doaj.org/article/a67a481efbd34bd0ba47df3d1ca1364f
Autor:
Daan R. M. G. Ophelders, Agnes W. Boots, Matthias C. Hütten, Salwan Al-Nasiry, Reint K. Jellema, Owen B. Spiller, Frederik-Jan van Schooten, Agnieszka Smolinska, Tim G. A. M. Wolfs
Publikováno v:
Frontiers in Pediatrics, Vol 9 (2021)
Chorioamnionitis is a major risk factor for preterm birth and an independent risk factor for postnatal morbidity for which currently successful therapies are lacking. Emerging evidence indicates that the timing and duration of intra-amniotic infectio
Externí odkaz:
https://doaj.org/article/ca67e004cb8e4a74ae8b860223421b3a
Autor:
Tammo Delhaas, Peter Andriessen, Judith Oeh van Laar, Rik Vullings, Ben Jm Hermans, Hendrik J Niemarkt, Reint K Jellema, Daan Rmg Ophelders, Tim Gam Wolfs, Boris W Kramer, Alex Zwanenburg
Publikováno v:
PLoS ONE, Vol 14, Iss 8, p e0221220 (2019)
The conclusion of our recent paper that performance of the STAN device in clinical practice is potentially limited by high false-negative and high false-positive STAN-event rates and loss of ST waveform assessment capacity during severe hypoxemia, ev
Externí odkaz:
https://doaj.org/article/549484c31d2b4e2c877b3dad57002d52
Autor:
Daan R.M.G. Ophelders, Tim G.A.M. Wolfs, Reint K. Jellema, Alex Zwanenburg, Peter Andriessen, Tammo Delhaas, Anna-Kristin Ludwig, Stefan Radtke, Vera Peters, Leon Janssen, Bernd Giebel, Boris W. Kramer
Publikováno v:
Stem Cells Translational Medicine, Vol 5, Iss 6, Pp 754-763 (2016)
Preterm neonates are susceptible to perinatal hypoxic‐ischemic brain injury, for which no treatment is available. In a preclinical animal model of hypoxic‐ischemic brain injury in ovine fetuses, we have demonstrated the neuroprotective potential
Externí odkaz:
https://doaj.org/article/29030b3ea97e4a9a974183f7346a8ae7
Autor:
Maria Nikiforou, Carolin Willburger, Anja E de Jong, Nico Kloosterboer, Reint K Jellema, Daan R M G Ophelders, Harry W M Steinbusch, Boris W Kramer, Tim G A M Wolfs
Publikováno v:
Molecular Medicine, Vol 22, Iss 1, Pp 244-257 (2016)
Abstract Perinatal asphyxia, a condition of impaired gas exchange during birth, leads to fetal hypoxia-ischemia (HI) and is associated with postnatal adverse outcomes including intestinal dysmotility and necrotizing enterocolitis. Evidence from adult
Externí odkaz:
https://doaj.org/article/d19ff9506de94dbbb83f60c44dcfc506
Autor:
Daan R.M.G. Ophelders, Ruth Gussenhoven, Luise Klein, Reint K. Jellema, Rob J.J. Westerlaken, Matthias C. Hütten, Jeroen Vermeulen, Guido Wassink, Alistair J. Gunn, Tim G.A.M. Wolfs
Publikováno v:
Cells, Vol 9, Iss 8, p 1871 (2020)
With a worldwide incidence of 15 million cases, preterm birth is a major contributor to neonatal mortality and morbidity, and concomitant social and economic burden Preterm infants are predisposed to life-long neurological disorders due to the immatu
Externí odkaz:
https://doaj.org/article/bb35dfa2bba94f72963d37b4664da72a
Autor:
Peter Andriessen, Alex Zwanenburg, Judith O E H van Laar, Rik Vullings, Ben J M Hermans, Hendrik J Niemarkt, Reint K Jellema, Daan R M G Ophelders, Tim G A M Wolfs, Boris W Kramer, Tammo Delhaas
Publikováno v:
PLoS ONE, Vol 13, Iss 4, p e0195978 (2018)
INTRODUCTION:The inconclusive clinical results for ST-waveform analysis (STAN) in detecting fetal hypoxemia may be caused by the signal processing of the STAN-device itself. We assessed the performance of a clinical STAN device in signal processing a
Externí odkaz:
https://doaj.org/article/d80fbcec25894189bab58b0501a83a60
Autor:
Mette van de Meent, Dianne G. Kleuskens, Wessel Ganzevoort, Sanne J. Gordijn, Elisabeth M. W. Kooi, Wes Onland, Bas B. van Rijn, Johannes J. Duvekot, René F. Kornelisse, Salwan Al-Nasiry, Reint K. Jellema, H. Marieke Knol, Gwendolyn T. R. Manten, Susanne M. Mulder-de Tollenaer, Jan B. Derks, Floris Groenendaal, Mireille N. Bekker, Ewoud Schuit, A. Titia Lely, Judith Kooiman
Publikováno v:
BMJ Open, 13(3):e070729. BMJ PUBLISHING GROUP
BMJ open, 13(3):e070729. BMJ Publishing Group
BMJ Open, 13(3):e070729. BMJ Publishing Group
BMJ open, 13(3):e070729. BMJ Publishing Group
BMJ Open, 13(3):e070729. BMJ Publishing Group
IntroductionEarly-onset fetal growth restriction (FGR) requires timely, often preterm, delivery to prevent fetal hypoxia causing stillbirth or neurologic impairment. Antenatal corticosteroids (CCS) administration reduces neonatal morbidity and mortal
Autor:
Tim G. A. M. Wolfs, Kay Pieterman, Robert W. Mays, Reint K. Jellema, Boris W. Kramer, Jeroen Dudink, Martin Lammens, Ruth Gussenhoven, Daan R. M. G. Ophelders, Luc J. I. Zimmermann
Publikováno v:
Stem Cells Translational Medicine
Stem Cells Translational Medicine, 10(1), 57-67. AlphaMed Press
Stem cells translational medicine, 10(1), 57-67. John Wiley & Sons Ltd.
Stem Cells Translational Medicine, 10(1), 57-67. AlphaMed Press
Stem cells translational medicine, 10(1), 57-67. John Wiley & Sons Ltd.
Involvement of the cerebellum in the pathophysiology of hypoxic‐ischemic encephalopathy (HIE) in preterm infants is increasingly recognized. We aimed to assess the neuroprotective potential of intravenously administered multipotent adult progenitor