Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Reinmar, Hager"'
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 18 (2024)
Voltage-gated potassium channels are a widely distributed subgroup of potassium channels responsible for the efflux of potassium in the repolarisation of the cell membrane, and hence contribute to the latency and propagation of action potentials. As
Externí odkaz:
https://doaj.org/article/326c09a8658b4338b36f2c2b029151d1
Autor:
Ugne Simanaviciute, Harry G. Potter, Reinmar Hager, Jocelyn Glazier, Emma Hodson-Tole, John Gigg, Robyn Grant
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 39, Iss , Pp 100807- (2024)
Poly I:C rat offspring are used to investigate the effects of in utero exposure to maternal immune activation (MIA) and have been suggested as a model of neurodevelopmental disorders (NDD). The behavioural symptoms of this model are diverse and can v
Externí odkaz:
https://doaj.org/article/9cb1c92b53d44a8ca9abffe37dce1c05
Publikováno v:
Child and Adolescent Psychiatry and Mental Health, Vol 16, Iss 1, Pp 1-22 (2022)
Abstract Background Resilience is broadly defined as the ability to maintain or regain functioning in the face of adversity. Recent work to harmonise the quantification and definition of resilience quantifies resilience as the residual variance in ps
Externí odkaz:
https://doaj.org/article/71320e711a88425ba965a66c8b23ec8a
Publikováno v:
BMC Ecology and Evolution, Vol 22, Iss 1, Pp 1-12 (2022)
Abstract Background Host-parasite interactions represent complex co-evolving systems in which genetic and associated phenotypic variation within a species can significantly affect selective pressures on traits, such as host immunity, in the other. Wh
Externí odkaz:
https://doaj.org/article/756fdaa87fdd4c3a97fe076ae4fe4203
Publikováno v:
Frontiers in Neuroscience, Vol 17 (2023)
The adult brain is a complex structure with distinct functional sub-regions, which are generated from an initial pool of neural epithelial cells within the embryo. This transition requires a number of highly coordinated processes, including neurogene
Externí odkaz:
https://doaj.org/article/229cdda3830449e79256fc7ec719dbc1
Publikováno v:
PLoS ONE, Vol 18, Iss 10, p e0282449 (2023)
Climatic changes, such as heatwaves, pose unprecedented challenges for insects, as escalated temperatures above the thermal optimum alter insect reproductive strategies and energy metabolism. While thermal stress responses have been reported in diffe
Externí odkaz:
https://doaj.org/article/b5fbdec20128400ca3189ef6eb8ccb5c
Autor:
Jarred M. Lorusso, Rebecca M. Woods, Francesca McEwan, Jocelyn D. Glazier, Joanna C. Neill, Michael Harte, Reinmar Hager
Publikováno v:
Brain, Behavior, & Immunity - Health, Vol 25, Iss , Pp 100514- (2022)
Schizophrenia and other neurodevelopmental disorders often have very heterogeneous symptoms, especially regarding cognition: while some individuals may exhibit deficient cognition, others are relatively unaffected. Studies using developmental animal
Externí odkaz:
https://doaj.org/article/defa50170c71470982aef4f4f0339b37
Publikováno v:
Epigenetics, Vol 16, Iss 3, Pp 313-326 (2021)
It is increasingly recognized that epigenetic mechanisms play a key role in acclimatization and adaptation to thermal stress in invertebrates. DNA methylation and its response to temperature variation has been poorly studied in insects. Here, we inve
Externí odkaz:
https://doaj.org/article/436d488fa42d4cdc99357001912abd6b
Publikováno v:
Frontiers in Psychiatry, Vol 13 (2022)
Resilience is broadly defined as the ability to maintain or regain functioning in the face of adversity and is influenced by both environmental and genetic factors. The identification of specific genetic factors and their biological pathways underpin
Externí odkaz:
https://doaj.org/article/62472ced7a8248b8bc2a394bc475ac3c
Autor:
Rebecca M. Woods, Jarred M. Lorusso, Isabella Harris, Hager M. Kowash, Christopher Murgatroyd, Joanna C. Neill, Jocelyn D. Glazier, Michael Harte, Reinmar Hager
Publikováno v:
Biomolecules, Vol 13, Iss 3, p 489 (2023)
Exposure to maternal immune activation (MIA) in utero significantly elevates the risk of developing schizophrenia and other neurodevelopmental disorders. To understand the biological mechanisms underlying the link between MIA and increased risk, prec
Externí odkaz:
https://doaj.org/article/46d2a050e91546bc912de2571fe2ad4c