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of 10 247
pro vyhledávání: '"Reinisch, A"'
New medical treatment development requires multiple phases of clinical trials. Despite the significant human and financial costs of bringing a drug to market, less than 20% of drugs in testing will make it from the first phase to final approval. Rece
Externí odkaz:
http://arxiv.org/abs/2408.10995
Autor:
Volker Möbus, Hans-Joachim Lück, Ekkehart Ladda, Peter Klare, Knut Engels, Marcus Schmidt, Andreas Schneeweiss, Eva-Maria Grischke, Grischa Wachsmann, Helmut Forstbauer, Michael Untch, Frederik Marmé, Jens-Uwe Blohmer, Christian Jackisch, Jens Huober, Elmar Stickeler, Mattea Reinisch, Theresa Link, Bruno Sinn, Wolfgang Janni, Carsten Denkert, Sabine Seiler, Christine Solbach, Sabine Schmatloch, Julia Rey, Sibylle Loibl
Publikováno v:
npj Breast Cancer, Vol 10, Iss 1, Pp 1-10 (2024)
Abstract GAIN-2 trial evaluated the optimal intense dose-dense (idd) strategy for high-risk early breast cancer. This study reports the secondary endpoints pathological complete response (pCR) and overall survival (OS). Patients (n = 2887) were rando
Externí odkaz:
https://doaj.org/article/b93eb5cc3e364be681372848cc75b63c
Autor:
Fanomezana M. Ranaivoson, Rieke Bande, Isabell Cardaun, Antonio De Riso, Annette Gärtner, Pui Loke, Christina Reinisch, Prasuna Vogirala, Edward Beaumont
Publikováno v:
IUCrJ, Vol 11, Iss 3, Pp 395-404 (2024)
Human peptidylarginine deiminase isoform VI (PAD6), which is predominantly limited to cytoplasmic lattices in the mammalian oocytes in ovarian tissue, is essential for female fertility. It belongs to the peptidylarginine deiminase (PAD) enzyme family
Externí odkaz:
https://doaj.org/article/b9751cfa701542cf81ac2d65fef67ad1
Autor:
Laurent Peyrin‐Biroulet, Perttu Arkkila, Alessandro Armuzzi, Silvio Danese, Marc Ferrante, Jordi Guardiola, Jørgen Jahnsen, Edouard Louis, Milan Lukáš, Walter Reinisch, Xavier Roblin, Philip J Smith, Taek Kwon, Jeeyoung Kim, Sangwook Yoon, Dong-Hyeon Kim, Raja Atreya
Publikováno v:
BMC Gastroenterology, Vol 24, Iss 1, Pp 1-12 (2024)
Abstract Background While indirect comparison of infliximab (IFX) and vedolizumab (VDZ) in adults with Crohn’s disease (CD) or ulcerative colitis (UC) shows that IFX has better effectiveness during induction, and comparable efficacy during maintena
Externí odkaz:
https://doaj.org/article/5d1ccaccfa3b4ae6bc5630baead360c9
Autor:
Isabel Reinisch, Helene Michenthaler, Alba Sulaj, Elisabeth Moyschewitz, Jelena Krstic, Markus Galhuber, Ruonan Xu, Zina Riahi, Tongtong Wang, Nemanja Vujic, Melina Amor, Riccardo Zenezini Chiozzi, Martin Wabitsch, Dagmar Kolb, Anastasia Georgiadi, Lisa Glawitsch, Ellen Heitzer, Tim J. Schulz, Michael Schupp, Wenfei Sun, Hua Dong, Adhideb Ghosh, Anne Hoffmann, Dagmar Kratky, Laura C. Hinte, Ferdinand von Meyenn, Albert J. R. Heck, Matthias Blüher, Stephan Herzig, Christian Wolfrum, Andreas Prokesch
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract In obesity, sustained adipose tissue (AT) inflammation constitutes a cellular memory that limits the effectiveness of weight loss interventions. Yet, the impact of fasting regimens on the regulation of AT immune infiltration is still elusive
Externí odkaz:
https://doaj.org/article/84abdd4dbbbf4fedab68791a6e68856d
Autor:
Reinisch, Gilbert
We define a new quantum Hermitian operator (namely, the energy variance operator) which is simply duplicated from the statistical definition of energy variance in classical physics. Its expectation value yields the standard deviation of the energy ab
Externí odkaz:
http://arxiv.org/abs/2205.12763
Autor:
Bungenberg, Marc, Reinisch, August
This open access book considers the potential setup for a future Multilateral Investment Court (MIC). The option of an MIC was first discussed by the EU Commission in 2016 and has since been made an official element of the EU Common Commercial Policy
Externí odkaz:
http://library.oapen.org/handle/20.500.12657/23089
Autor:
Magro, Fernando, Protic, Marijana, De Hertogh, Gert, Chan, Lai Shan, Pollack, Paul, Jairath, Vipul, Carlier, Hilde, Hon, Emily, Feagan, Brian G., Harpaz, Noam, Pai, Rish, Reinisch, Walter
Publikováno v:
In Clinical Gastroenterology and Hepatology September 2024 22(9):1878-1888
Autor:
Narula, Neeraj, Wong, Emily C.L., Dulai, Parambir S., Patel, Jaiminkumar, Marshall, John K., Yzet, Clara, Jairath, Vipul, Ungaro, Ryan, Colombel, Jean-Frederic, Reinisch, Walter
Publikováno v:
In Clinical Gastroenterology and Hepatology August 2024 22(8):1687-1696
Autor:
Schreiber, Stefan, D'Haens, Geert, Cummings, Fraser, Irving, Peter M., Ye, Byong Duk, Ben-Horin, Shomron, Kim, Dong-Hyeon, Jeong, Ae Lee, Reinisch, Walter
Publikováno v:
In Digestive and Liver Disease July 2024 56(7):1204-1212