Zobrazeno 1 - 10
of 58
pro vyhledávání: '"Reinilde Heyrman"'
Publikováno v:
Journal of Clinical Hypertension (Greenwich, Conn.)
The objective of this prespecified TRINITY study subgroup analysis was to assess the efficacy and safety of triple-combination treatment with olmesartan medoxomil (OM) 40 mg, amlodipine besylate (AML) 10 mg, and hydrochlorothiazide (HCTZ) 25 mg vs th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a955d84e2a9f23dc1dcec41b5314fa1
http://europepmc.org/articles/PMC3908371
http://europepmc.org/articles/PMC3908371
Autor:
Shashank Rohatagi, Helen Moore, Reinilde Heyrman, SaeHeum Song, Michelle Green, Raymond Miller, Timothy J. Carrothers, James Lee, Michael Melino, Daniel E. Salazar, Antonia Wang, Manini Patel
Publikováno v:
Clinical Pharmacology in Drug Development. 2:103-112
CS-8635, a fixed-dose triple combination of olmesartan, amlodipine, and hydrochlorothiazide, was developed to address the growing need for additional blood pressure (BP) reduction in patients not controlled with dual-combination therapies. Prior to P
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6b55fd7f812b63ff305ba02e447a5756
https://doi.org/10.1002/cpdd.17
https://doi.org/10.1002/cpdd.17
Autor:
Pamela S. Douglas, Jay H. Traverse, Jarosław D. Kasprzak, Victor Guetta, Reinilde Heyrman, Jerome Roncalli, Jennifer A. White, Timothy D. Henry, Uwe Zeymer, C. Michael Gibson, Oscar H. Kracoff, Jingyu Liu, Howard Levy, Derek P. Chew, Sunil V. Rao, Norbert Frey, Mitchell W. Krucoff, Paul Vermeersch, Jose Lopez-Sendon, Hussein R. Al-Khalidi, Jean Francois Tanguay
Publikováno v:
Journal of the American College of Cardiology. 68(7)
Background Bioabsorbable cardiac matrix (BCM) is a novel device that attenuates adverse left ventricular (LV) remodeling after large myocardial infarctions in experimental models. Objectives This study aimed to analyze whether BCM, compared with sali
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33bb83cb955be30a582e2540336cdb51
https://pubmed.ncbi.nlm.nih.gov/27515332
https://pubmed.ncbi.nlm.nih.gov/27515332
Autor:
Thomas G. Wells, Douglas L. Blowey, Reinilde Heyrman, Daniel E. Salazar, Janice E. Sullivan, Joseph R. Sherbotie, SaeHeum Song, Shashank Rohatagi, Jeffrey L. Blumer
Publikováno v:
Pediatric Drugs. 14:401-409
Background: The prevalence and importance of hypertension in younger patients is becoming increasingly recognized; however, only a limited number of clinical trials have been conducted in the pediatric population. Objective: The aim of this study was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4db304e5a23e5af1e64ec3c7a7759b50
https://doi.org/10.2165/11631450-000000000-00000
https://doi.org/10.2165/11631450-000000000-00000
Autor:
Reinilde Heyrman, Suzanne Oparil, Joseph L. Izzo, Thomas Littlejohn, Steven G. Chrysant, Victor Fernandez, Michael Melino, James Lee, Dean J. Kereiakes
Publikováno v:
American Journal of Cardiovascular Drugs. 12:233-243
Background Although awareness of hypertension in Black patients has increased, blood pressure (BP) is frequently inadequately controlled. Objective This prespecified subgroup analysis of the TRINITY study evaluated the efficacy and safety of olmesart
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61fcb37397d366c41361fc5f48ea7fb3
https://doi.org/10.1007/bf03261832
https://doi.org/10.1007/bf03261832
Autor:
Suzanne Oparil, Reinilde Heyrman, Steven G. Chrysant, Thomas Littlejohn, Victor Fernandez, Dean J. Kereiakes, James Lee, Joseph L. Izzo, Michael Melino
Publikováno v:
The Journal of Clinical Hypertension. 14:149-157
J Clin Hypertens (Greenwich). 2012;14:149-157. ©2012 Wiley Periodicals, Inc. Most patients with hypertension require combination therapy in order to achieve blood pressure (BP) goals. This 40-week open-label extension of the 12-week double-blind Tri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8937da794e104cc3b415632acebc08b
https://doi.org/10.1111/j.1751-7176.2011.00588.x
https://doi.org/10.1111/j.1751-7176.2011.00588.x
Autor:
D R Wada, Timothy J. Carrothers, Daniel E. Salazar, J Shi, Shashank Rohatagi, SaeHeum Song, Reinilde Heyrman
Publikováno v:
Clinical Pharmacology & Therapeutics. 91:250-256
Modeling and simulation were used extensively in the development of an indication for the use of olmesartan medoxomil in pediatric patients with hypertension. Simulations based on models developed in adult patients indicated that two dose groups were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a7c1aa45b4f0b3430391e237e569880
https://doi.org/10.1038/clpt.2011.220
https://doi.org/10.1038/clpt.2011.220
Autor:
Suzanne Oparil, Steven G. Chrysant, Michael Melino, Reinilde Heyrman, Thomas Littlejohn, Victor Fernandez, James Lee, Dean J. Kereiakes, Joseph L. Izzo
Publikováno v:
The Journal of Clinical Hypertension. 13:873-880
This 12-week, multicenter, randomized, double-blinded, 4-arm study in 440 patients with moderate to severe hypertension compared ambulatory blood pressure (ABP) responses with a triple-combination regimen (olmesartan medoxomil [OM] 40 mg, amlodipine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5104eb39809904d604e20517d3d4818a
https://doi.org/10.1111/j.1751-7176.2011.00544.x
https://doi.org/10.1111/j.1751-7176.2011.00544.x
Autor:
Reinilde Heyrman, Steven G. Chrysant, James Lee, Sulekha Karki, Michael Melino, Suzanne Oparil
Publikováno v:
Journal of Human Hypertension
A prespecified subgroup analysis of a 44-week open-label extension study is presented. The efficacy and safety of the combination of amlodipine (AML) + olmesartan medoxomil (OM), with and without the addition of hydrochlorothiazide (HCTZ), were inves
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44895f6eb3a3e830429a8182203d711e
https://doi.org/10.1038/jhh.2010.16
https://doi.org/10.1038/jhh.2010.16
Publikováno v:
Journal of Human Hypertension
Hypertension is particularly prevalent in patients aged ≥65 years, those with a body mass index ≥30 kg m(-2), Blacks and those with type II diabetes. Here we report a prespecified secondary analysis of the efficacy of amlodipine (10 mg day(-1)),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::11ddb0a9ec2b976fa2c101834a6812c2
https://doi.org/10.1038/jhh.2010.5
https://doi.org/10.1038/jhh.2010.5