Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Reinier C.A. van Ham"'
Publikováno v:
Nucleic Acids Research. 19:6301-6308
The human XPBC/ERCC-3 was cloned by virtue of its ability to correct the excision repair defect of UV-sensitive rodent mutants of complementation group 3. The gene appeared to be in addition implicated in the human, cancer prone repair disorder xerod
Autor:
Reinier C.A. van Ham, Dirk Bootsma, Wim Vermeulen, Geert Weeda, Alex J. van der Eb, Jan H.J. Hoeijmakers
Publikováno v:
Cell. 62:777-791
The human gene ERCC-3 specifically corrects the defect in an early step of the DNA excision repair pathway of UV-sensitive rodent mutants of complementation group 3. The predicted 782 amino acid ERCC-3 protein harbors putative nucleotide, chromatin,