Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Reinhold Welker"'
Publikováno v:
The EMBO Journal. 22:1707-1715
Mature, infectious HIV-1 particles contain a characteristic cone-shaped core that encases the viral RNA and replication proteins. The architectures of mature virions and isolated cores were studied using cryo-electron microscopy. The average size ( a
Autor:
Markus Hildinger, Reinhold Welker, Barbara S. Schnierle, Sonja Thaler, Patricia Schult-Dietrich, Dorothee von Laer, Matthias T. Dittmar, Boris Fehse, Gabriela Stiegler
Publikováno v:
Journal of Virology. 75:3038-3042
Peptides derived from the heptad repeats of human immunodeficiency virus (HIV) gp41 envelope glycoprotein, such as T20, can efficiently inhibit HIV type 1 (HIV-1) entry. In this study, replication of HIV-1 was inhibited more than 100-fold in a T-help
Publikováno v:
Biochemical Journal. 343:199-207
Diphtheria toxin enters the cytosol of mammalian cells where it inhibits cellular protein synthesis, leading to cell death. Recently we found that the addition of a signal for N-end-rule-mediated protein degradation to diphtheria toxin substantially
Publikováno v:
Journal of Virology. 71:5209-5217
Retrovirus morphogenesis involves assembly of structural Gag polyproteins with subsequent budding from the plasma membrane, followed by proteolytic cleavage by the viral proteinase (PR) and extracellular maturation to the infectious virion. Intracist
Publikováno v:
Virology
The Nef protein of primate immunodeficiency viruses is essential for establishing a highly productive pathogenic infection in vivo. In tissue culture, Nef is not required for infection but enhances viral infectivity. This effect is most pronounced in
Publikováno v:
Viral Infections and Treatment
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ecd892e499af1b5a2dcd7f0b140cd19a
https://doi.org/10.1201/b14823
https://doi.org/10.1201/b14823
Autor:
Akiko Iwasaki, Steffen Mueller, Melissa M. Linehan, Akio Nomoto, Eckard Wimmer, Reinhold Welker
Publikováno v:
The Journal of infectious diseases. 186(5)
Oral transmission of poliovirus is restricted to humans and certain primate species. The expression of the human poliovirus receptor (CD155) within gastrointestinal-associated lymphoid tissues from species that are susceptible (human) or resistant (r
Publikováno v:
The Journal of biological chemistry. 277(10)
The cellular receptor for poliovirus CD155 (or PVR) is the founding member of a new class of membrane-associated immunoglobulin-like proteins, which include the mouse tumor-associated antigen E4 (Tage4) and three proteins termed "nectins." Using a ye
Publikováno v:
Journal of virology. 75(22)
Nuclear export of incompletely spliced RNAs is a prerequisite for retroviral replication. Complex retroviruses like human immunodeficiency virus (HIV) encode a viral transport factor (Rev), which binds to its target sequence on the RNA genome and dir