Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Reinhold J, Hutz"'
Autor:
Qing Liu, Jan M Spitsbergen, Ronan Cariou, Chun-Yuan Huang, Nan Jiang, Giles Goetz, Reinhold J Hutz, Peter J Tonellato, Michael J Carvan
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e100910 (2014)
The goal of this project was to investigate the effects and possible developmental disease implication of chronic dietary TCDD exposure on global gene expression anchored to histopathologic analysis in juvenile zebrafish by functional genomic, histop
Externí odkaz:
https://doaj.org/article/216467fba74c41be8d20e9f6cd238e4d
Publikováno v:
Reproductive Toxicology. 52:57-61
2,3,7,8-Tetrachlorodibenzo- p -dioxin (TCDD) is the most toxic congener of the polyhalogenated aromatic hydrocarbons (PAH), which causes anatomical abnormalities and developmental defects, impairs ovulation and reduces fertility. TCDD's endocrine-dis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a616e0b14de15f7be215806249bb1475
https://doi.org/10.1016/j.reprotox.2015.02.003
https://doi.org/10.1016/j.reprotox.2015.02.003
Publikováno v:
Reproduction, Fertility and Development. 31:1017
3-nitropropionic acid (3-NPA) is known to be a mitochondrial toxin produced by plants and fungi, which may produce DNA damage in cells. However, studies of its reproductive toxicology are lacking. We know that poly(ADP-ribose) polymerase (PARP) plays
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::416b21f1e2db8c6f80a9caa32ace9e02
https://doi.org/10.1071/rd18406
https://doi.org/10.1071/rd18406
Autor:
Michael J. Carvan, Qing Liu, Jan M. Spitsbergen, Tiago S. Hori, Jeremy K. Larson, Reinhold J. Hutz, Giles Goetz, Steven Geis, Matthew L. Rise, Joseph McGraw, Mark Mieritz
Publikováno v:
Aquatic Toxicology. :356-368
The goal of this project was to use functional genomic methods to identify molecular biomarkers as indicators of the impact of TCDD exposure in rainbow trout. Specifically, we investigated the effects of chronic dietary TCDD exposure on whole juvenil
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8829264912bf58848b734734acae4166
https://doi.org/10.1016/j.aquatox.2013.06.018
https://doi.org/10.1016/j.aquatox.2013.06.018
Autor:
Zhengrong Zhou, Fangxiong Shi, Xin Zhou, Hao Wang, Quanwei Wei, Reinhold J. Hutz, Pan Huang, Liang Zhang
Publikováno v:
International Journal of Molecular Medicine. 30:650-658
Insulin-like growth factor 1 (IGF-1) and Akt [also known as protein kinase B (PKB)] proteins have been reported to exhibit gastroprotective effects by reducing water immersion and restraint stress (WRS)-induced gastric mucosal cellular apoptosis. To
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e9eabe152fa41dde189e7f3768f4c9e
https://doi.org/10.3892/ijmm.2012.1041
https://doi.org/10.3892/ijmm.2012.1041
Autor:
Reinhold J. Hutz, Rosemary Stelzer
Publikováno v:
Journal of Reproduction and Development. 55:685-690
Nanoparticle technology refers to research and technology developed at the atomic or molecular level for materials of approximately 1-100 nm in length. Through accidental or involuntary exposure, nanoparticles are potentially toxic to the body, inclu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::997c4f5221b6f3603aee68fa3b2ebcba
https://doi.org/10.1262/jrd.20241
https://doi.org/10.1262/jrd.20241
Autor:
Gentao Liu, Yongqing Jiang, Zhengchao Wang, Reinhold J. Hutz, Zhuang Xie, Wenbin Liu, Fangxiong Shi, Xuebin Li
Publikováno v:
Zoological Science. 22:1339-1346
FoxO1 is a transcription factor implicated in a multitude of physiological processes including cell cycle progression, apoptosis and insulin signaling. Recent findings indicate that FoxO1 is a key regulator during the proliferation and maturation of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::acc13bf3a402d723662616dae2307286
https://doi.org/10.2108/zsj.22.1339
https://doi.org/10.2108/zsj.22.1339
Publikováno v:
Toxicological Sciences. 87:497-507
TCDD (2,3,7,8-tetrachlorodibenzo-p-dioxin) is a reproductive toxicant and endocrine disruptor in nearly all vertebrates; however, the mechanisms by which TCDD alters the reproductive system is not well understood. The zebrafish provides a powerful ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::15f3098f01f6b63474e81f4b85aa3af8
https://doi.org/10.1093/toxsci/kfi201
https://doi.org/10.1093/toxsci/kfi201
Publikováno v:
Neonatology. 88:66-72
Background: Intrauterine growth retardation (IUGR) is a common problem in human and other species and increases the risk of death of the fetus and newborn during the perinatal period. Objectives: This study was conducted to examine the influences of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db420043bad850ccd3245b480de168ea
https://doi.org/10.1159/000084645
https://doi.org/10.1159/000084645
Publikováno v:
Reproductive Toxicology. 17:567-573
Polychlorinated biphenyls (PCBs) are ubiquitous man-made toxicants capable of endocrine disruption. Studies in several species have shown that exposure to PCBs and their hydroxylated metabolites reduces fecundity and decreases circulating concentrati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5c21e70bbaa147b146d2db24ddb39f6a
https://doi.org/10.1016/s0890-6238(03)00095-9
https://doi.org/10.1016/s0890-6238(03)00095-9