Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Reinhold Hofbauer"'
Publikováno v:
BioTechniques, Vol 26, Iss 5, Pp 846-850 (1999)
Externí odkaz:
https://doaj.org/article/5541e6e6f7594b18adfee967c61d0d11
Background: L‑carnitine is an indispensable metabolite in eukaryotic cells, which facilitates transport of long‑chain fatty acids into the mitochondrial matrix for subsequent β-oxidation and helps to safeguard the acetyl-CoA level. Additionally,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fbd913663c250189b137cb79f309f2e1
https://doi.org/10.21203/rs.2.14505/v1
https://doi.org/10.21203/rs.2.14505/v1
Autor:
Reinhold Hofbauer, Sylvia Brunner, Alison C. Agu, Alfred Lohninger, Alzbeta Godarova, Elke Litzlbauer
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 136:1349-1363
In order to analyze the biological influence of carnitine on the transcriptional regulation of mitochondrial carnitine acetyltransferase (CRAT) and carnitine palmitoyltransferases (CPT1A and CPT2) in conditions simulating carnitine deficiency in vivo
Autor:
Elke Litzlbauer, Herbert Staniek, Hermann Mascher, Alfred Lohninger, Alma Sendic, Daniel Mascher, Reinhold Hofbauer, Heinrich Bergmüler, Michael Eder, Cornelia Schwieglhofer, Dietmar Blesky
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 136:1425-1442
Endurance exercise training is known to increase fatty acid (FA) oxidation during exercise and to stimulate mRNA synthesis of mitochondrial carnitine acyltransferases in skeletal muscle. To test the hypothesis that long-term endurance training induce
Autor:
Alison C. Agu, Reinhold Hofbauer, Josef Kletzmayr, Alzbeta Godarova, Alfred Lohninger, Elke Litzlbauer
Publikováno v:
Monatshefte für Chemie - Chemical Monthly. 136:1509-1521
We analysed the effects of carnitine substitution on carnitine acyltransferases in Rat1-cells, mouse NIH3T3, and human MRC5 fibroblasts serving as reporter cells. For cultivation we used human sera isolated from well-defined conditions of carnitine d
Autor:
Seyedhossein Aharinejad, K. Paya, Dietmar Abraham, D. Pullirsch, Reinhold Hofbauer, Mitra Fakhari
Publikováno v:
Journal of Pediatric Surgery. 37:582-587
Background: Angiogenesis is essential for tumor growth and relies on the production of angiogenic factors. Vascular endothelial growth factor (VEGF) is a major regulator of angiogenesis that binds to tyrosine kinase receptors Flt-1 and KDR. The inter
Publikováno v:
BMC Genomics
Background The carnitine acetyltransferase (CrAT) is a mitochondrial matrix protein that directly influences intramitochondrial acetyl-CoA pools. Murine CrAT is encoded by a single gene located in the opposite orientation head to head to the PPP2R4 g
Autor:
Hannes Traxler, Roland Blumer, G. Laufer, Romana Schäfer, Alfred Kocher, Seyedhossein Aharinejad, Aurelia Miksovsky, D. Pullirsch, Shahrokh Taghavi, Reinhold Hofbauer, Dietmar Abraham, Alexandrowicz R
Publikováno v:
Transplantation. 72:1043-1049
Little is known about the long-term impact of cardiac transplantation on activity and modifications of endothelin (ET)-1 system, vascular endothelial growth factor (VEGF), and mitochondrial metabolism and morphology in patients with ischemic cardiomy
Autor:
Reinhold Hofbauer, Birgitte Munch-Petersen, Jacob Fromberg Christensen, Tina Kristensen, Dvora Berenstein
Publikováno v:
Journal of Biological Chemistry. 275:32187-32192
Cytosolic thymidine kinase (TK1) cDNA from human lymphocytes was cloned, expressed in Escherichia coli, purified, and characterized with respect to the ATP effect on thymidine affinity and oligomerization. Sequence analysis of this lymphocyte TK1 cDN
Publikováno v:
Protein Expression and Purification. 5:432-441
Recombinant Herpes Simplex Virus Type 1 thymidine kinase (TK) was isolated in a fast and gentle two-step procedure from Escherichia coli as a thrombin cleavable fusion protein. The TK was expressed as an inducible glutathione S-acetyl transferase fus