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Vaccination with Mycoplasma pneumoniae membrane lipoproteins induces IL-17A driven neutrophilia that mediates Vaccine-Enhanced Disease.

Autor: Mara AB; Department of Pathobiology and Veterinary Science, 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA.; Center of Excellence for Vaccine Research (CEVR), 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA., Gavitt TD; Department of Pathobiology and Veterinary Science, 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA.; Center of Excellence for Vaccine Research (CEVR), 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA., Tulman ER; Department of Pathobiology and Veterinary Science, 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA.; Center of Excellence for Vaccine Research (CEVR), 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA., Miller JM; Department of Pathobiology and Veterinary Science, 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA.; Center of Excellence for Vaccine Research (CEVR), 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA., He W; Flow Cytometry Facility, Center for Open Research Resources and Equipment, 438 Whitney Rd Ext Unit 1149, Storrs, CT, 06269, USA., Reinhardt EM; Department of Pathobiology and Veterinary Science, 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA.; Connecticut Veterinary Medical Diagnostic Laboratory (CVMDL), 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA., Ozyck RG; Department of Pathobiology and Veterinary Science, 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA., Goodridge ML; Department of Pathobiology and Veterinary Science, 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA., Silbart LK; Department of Pathobiology and Veterinary Science, 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA.; Center of Excellence for Vaccine Research (CEVR), 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA.; Department of Allied Health, University of Connecticut, 358 Mansfield Rd, Unit-1101, Storrs, CT, 06269, USA., Szczepanek SM; Department of Pathobiology and Veterinary Science, 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA. steven.szczepanek@uconn.edu.; Center of Excellence for Vaccine Research (CEVR), 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA. steven.szczepanek@uconn.edu., Geary SJ; Department of Pathobiology and Veterinary Science, 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA. steven.geary@uconn.edu.; Center of Excellence for Vaccine Research (CEVR), 61N Eagleville Rd. Unit-3089, Storrs, CT, 06269, USA. steven.geary@uconn.edu.

Publikováno v: NPJ vaccines [NPJ Vaccines] 2022 Jul 29; Vol. 7 (1), pp. 86. Date of Electronic Publication: 2022 Jul 29.