Molecular basis of GDF15 induction and suppression by drugs in cardiomyocytes and cancer cells toward precision medicine.

Autor: Winter, Lisa-Maria¹ (AUTHOR), Reinhardt, Diana¹ (AUTHOR), Schatter, Ariane¹ (AUTHOR), Tissen, Vivien¹ (AUTHOR), Wiora, Heike¹ (AUTHOR), Gerlach, Daniel² (AUTHOR), Tontsch-Grunt, Ulrike² (AUTHOR), Colbatzky, Florian¹ (AUTHOR), Stierstorfer, Birgit¹ (AUTHOR), Yun, Seong-Wook¹ (AUTHOR) seong-wook.yun@boehringer-ingelheim.com

Publikováno v: Scientific Reports. 7/26/2023, Vol. 13 Issue 1, p1-13. 13p.

Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems

Autor: Nestor, Colm E, Ottaviano, Raffaele, Reinhardt, Diana, Cruickshanks, Hazel A, Mjoseng, Heidi K, McPherson, Rhoanne C, Lentini, Antonio, Thomson, John P, Dunican, Donncha S, Pennings, Sari, Anderton, Stephen M, Benson, Mikael, Meehan, Richard R

Publikováno v: Nestor, C E, Ottaviano, R, Reinhardt, D, Cruickshanks, H A, Mjoseng, H K, McPherson, R C, Lentini, A, Thomson, J P, Dunican, D S, Pennings, S, Anderton, S M, Benson, M & Meehan, R R 2015, ' Rapid reprogramming of epigenetic and transcriptional profiles in mammalian culture systems ', Genome Biology, vol. 16, no. 11, 11 . https://doi.org/10.1186/s13059-014-0576-y

BackgroundThe DNA methylation profile of mammalian cell lines differs from the primary tissue from which they were derived, exhibiting increasing divergence from the in vivo methylation profile with extended time in culture. Few studies have directly

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Two common endoglin mutations in families with hereditary hemorrhagic telangiectasia in the Netherlands Antilles: evidence for a founder effect.

Autor: Gallione, Carol J., Scheessele, Erin A., Reinhardt, Diana, Duits, Ashley J., Berg, Jonathan N., Westermann, Cornelius J.J., Marchuk, Douglas A.

Publikováno v: Human Genetics; Jul2000, Vol. 107 Issue 1, p40-44, 5p