Zobrazeno 1 - 10
of 153
pro vyhledávání: '"Reinhard Wallich"'
Autor:
Florian Röttgerding, Alex Wagemakers, Joris Koetsveld, Volker Fingerle, Michael Kirschfink, Joppe W. Hovius, Peter F. Zipfel, Reinhard Wallich, Peter Kraiczy
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-15 (2017)
Abstract Borrelia (B.) miyamotoi, an emerging tick-borne relapsing fever spirochete, resists complement-mediated killing. To decipher the molecular principles of immune evasion, we sought to identify determinants contributing to complement resistance
Externí odkaz:
https://doaj.org/article/d332e145360d4ee0b985697b6a40fcbf
Autor:
Durdica Marosevic, Gabriele Margos, Reinhard Wallich, Andreas Wieser, Andreas Sing, Volker Fingerle
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 11, Iss 9, p e0005865 (2017)
Borrelia recurrentis is the causative agent of louse-borne relapsing fever, endemic to the Horn of Africa. New attention was raised in Europe, with the highest number of cases (n = 45) reported among migrants in 2015 in Germany and sporadically from
Externí odkaz:
https://doaj.org/article/3b6ea99a96044838895f6962448d8ce5
Autor:
Philipp Kolb, Jolanta Vorreiter, Jüri Habicht, Detlef Bentrop, Reinhard Wallich, Michael Nassal
Publikováno v:
FEBS Open Bio, Vol 5, Iss 1, Pp 42-55 (2015)
Ticks transmit numerous pathogens, including borreliae, which cause Lyme disease. Tick saliva contains a complex mix of anti‐host defense factors, including the immunosuppressive cysteine‐rich secretory glycoprotein Salp15 fromIxodes scapularis t
Externí odkaz:
https://doaj.org/article/b8ed4247025a40a9ab88107762147cbc
Publikováno v:
PLoS ONE, Vol 10, Iss 9, p e0136180 (2015)
Ticks are vectors for various, including pathogenic, microbes. Tick saliva contains multiple anti-host defense factors that enable ticks their bloodmeals yet also facilitate microbe transmission. Lyme disease-causing borreliae profit specifically fro
Externí odkaz:
https://doaj.org/article/128d01c022eb48459925b8d5a7b90094
Publikováno v:
PLoS ONE, Vol 9, Iss 3, p e90796 (2014)
Candida albicans is a major cause of invasive fungal infections worldwide. Upon infection and when in contact with human plasma as well as body fluids the fungus is challenged by the activated complement system a central part of the human innate immu
Externí odkaz:
https://doaj.org/article/e00bd37f75e04ecc989d14e7287910fa
Autor:
Jasmin Schwab, Claudia Hammerschmidt, Dania Richter, Christine Skerka, Franz-Rainer Matuschka, Reinhard Wallich, Peter F Zipfel, Peter Kraiczy
Publikováno v:
PLoS ONE, Vol 8, Iss 1, p e53659 (2013)
Spirochetes belonging to the Borrelia (B.) burgdorferi sensu lato complex differ in their resistance to complement-mediated killing, particularly in regard to human serum. In the present study, we elucidate the serum and complement susceptibility of
Externí odkaz:
https://doaj.org/article/47cc9e4df0a44d48875f737aad721b03
Autor:
Hannes U Eberhardt, Denise Buhlmann, Peter Hortschansky, Qian Chen, Sascha Böhm, Markus J Kemper, Reinhard Wallich, Andrea Hartmann, Teresia Hallström, Peter F Zipfel, Christine Skerka
Publikováno v:
PLoS ONE, Vol 8, Iss 11, p e78617 (2013)
Mutations and deletions within the human CFHR gene cluster on chromosome 1 are associated with diseases, such as dense deposit disease, CFHR nephropathy or age-related macular degeneration. Resulting mutant CFHR proteins can affect complement regulat
Externí odkaz:
https://doaj.org/article/0a3e82dd6e944352ab29effbc719de8a
Publikováno v:
PLoS ONE, Vol 8, Iss 5, p e63437 (2013)
Many pathogenic microorganisms express fibronectin-binding molecules that facilitate their adherence to the extracellular matrix and/or entry into mammalian cells. We have previously described a Borrelia recurrentis gene, cihC that encodes a 40-kDa s
Externí odkaz:
https://doaj.org/article/cdeec34e64924bada816146e272bc927
Autor:
Claudia Hammerschmidt, Teresia Hallström, Christine Skerka, Reinhard Wallich, Brian Stevenson, Peter F. Zipfel, Peter Kraiczy
Publikováno v:
Clinical and Developmental Immunology, Vol 2012 (2012)
Borrelia burgdorferi evades complement-mediated killing by interacting with complement regulators through distinct complement regulator-acquiring surface proteins (CRASPs). Here, we extend our analyses to the contribution of CRASP-4 in mediating comp
Externí odkaz:
https://doaj.org/article/3d9dac5ad8654a5891bda6784667aee9
Autor:
Corinna Siegel, Teresia Hallström, Christine Skerka, Hannes Eberhardt, Barbara Uzonyi, Tobias Beckhaus, Michael Karas, Reinhard Wallich, Brian Stevenson, Peter F Zipfel, Peter Kraiczy
Publikováno v:
PLoS ONE, Vol 5, Iss 10, p e13519 (2010)
One virulence property of Borrelia burgdorferi is its resistance to innate immunity, in particular to complement-mediated killing. Serum-resistant B. burgdorferi express up to five distinct complement regulator-acquiring surface proteins (CRASP) whic
Externí odkaz:
https://doaj.org/article/093d32e2843c4fb6adaeb67baa568d9e