Zobrazeno 1 - 10
of 133
pro vyhledávání: '"Reinhard Seifert"'
Autor:
Matthias Broser, Anika Spreen, Patrick E. Konold, Enrico Schiewer, Suliman Adam, Veniamin Borin, Igor Schapiro, Reinhard Seifert, John T. M. Kennis, Yinth Andrea Bernal Sierra, Peter Hegemann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-1 (2024)
Externí odkaz:
https://doaj.org/article/66437da637c848348ff049b21ce79cbc
Autor:
Matthias Broser, Anika Spreen, Patrick E. Konold, Enrico Schiewer, Suliman Adam, Veniamin Borin, Igor Schapiro, Reinhard Seifert, John T. M. Kennis, Yinth Andrea Bernal Sierra, Peter Hegemann
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-10 (2020)
Abstract The Rhizoclosmatium globosum genome encodes three rhodopsin-guanylyl cyclases (RGCs), which are predicted to facilitate visual orientation of the fungal zoospores. Here, we show that RGC1 and RGC2 function as light-activated cyclases only up
Externí odkaz:
https://doaj.org/article/10eb544325fe4b8da25b941e9130ed31
Autor:
Yinth Andrea Bernal Sierra, Benjamin R. Rost, Martin Pofahl, António Miguel Fernandes, Ramona A. Kopton, Sylvain Moser, Dominik Holtkamp, Nicola Masala, Prateep Beed, John J. Tukker, Silvia Oldani, Wolfgang Bönigk, Peter Kohl, Herwig Baier, Franziska Schneider-Warme, Peter Hegemann, Heinz Beck, Reinhard Seifert, Dietmar Schmitz
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-13 (2018)
Optogenetic tools enable precise experimental control of the behaviour of cells. Here, the authors introduce a genetically-encoded two-protein system that enables silencing of excitable cells such as neurons and cardiomyocytes using blue light, and d
Externí odkaz:
https://doaj.org/article/d8999362660741adba65546c0b941d4e
Autor:
Sahrai Saeed, Giuseppe Mancia, Ronak Rajani, Reinhard Seifert, Denise Parkin, John B. Chambers
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 7, Iss 22 (2018)
Background Exaggerated blood pressure response during exercise predicts future hypertension and cardiovascular events in general population and different patients groups. However, its clinical and prognostic implications in patients with aortic steno
Externí odkaz:
https://doaj.org/article/621a21cbb9674bd387db799eb2509933
Autor:
Espen Ø. Bjørnestad, Robert A. Borsholm, Gard F. T. Svingen, Eva R. Pedersen, Reinhard Seifert, Øivind Midttun, Per M. Ueland, Grethe S. Tell, Kaare H. Bønaa, Ottar Nygård
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 6, Iss 11 (2017)
BackgroundPlasma total homocysteine (tHcy) is related to plasma neopterin, an indicator of interferon‐γ‐mediated immune activation, and both biomarkers positively predict cardiovascular risk. We examined whether the association between tHcy and
Externí odkaz:
https://doaj.org/article/bae074dd08a44a2db42fd5dc7afead36
Autor:
Shatanik Mukherjee, Vera Jansen, Jan F Jikeli, Hussein Hamzeh, Luis Alvarez, Marco Dombrowski, Melanie Balbach, Timo Strünker, Reinhard Seifert, U Benjamin Kaupp, Dagmar Wachten
Publikováno v:
eLife, Vol 5 (2016)
The cellular messenger cAMP regulates multiple cellular functions, including signaling in cilia and flagella. The cAMP dynamics in these subcellular compartments are ill-defined. We introduce a novel FRET-based cAMP biosensor with nanomolar sensitivi
Externí odkaz:
https://doaj.org/article/aaf3386b6d7b47d1b78fa1f71fd7c228
Autor:
Heidi Borgeraas, Jens Kristoffer Hertel, Gard Frodahl Tveitevåg Svingen, Eva Ringdal Pedersen, Reinhard Seifert, Ottar Nygård, Jøran Hjelmesæth
Publikováno v:
PLoS ONE, Vol 11, Iss 3, p e0152029 (2016)
BackgroundAsymmetric dimethylarginine (ADMA) is associated with increased risk of atherosclerotic cardiovascular disease and mortality through inhibition of nitrogen oxide (NO) synthesis. As positive correlations between serum concentrations of NO an
Externí odkaz:
https://doaj.org/article/68a8fba08c404f84b85887e35431dcea
Autor:
Sylvia Fechner, Luis Alvarez, Wolfgang Bönigk, Astrid Müller, Thomas K Berger, Rene Pascal, Christian Trötschel, Ansgar Poetsch, Gabriel Stölting, Kellee R Siegfried, Elisabeth Kremmer, Reinhard Seifert, U Benjamin Kaupp
Publikováno v:
eLife, Vol 4 (2015)
Calcium in the flagellum controls sperm navigation. In sperm of marine invertebrates and mammals, Ca2+ signalling has been intensely studied, whereas for fish little is known. In sea urchin sperm, a cyclic nucleotide-gated K+ channel (CNGK) mediates
Externí odkaz:
https://doaj.org/article/5659ad2ef0964e8487bb8bca21e42599
Autor:
Hall Schartum-Hansen, Kjetil H Løland, Gard F T Svingen, Reinhard Seifert, Eva R Pedersen, Jan E Nordrehaug, Øyvind Bleie, Marta Ebbing, Christ Berge, Dennis W T Nilsen, Ottar Nygård
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0124611 (2015)
BACKGROUND:Loop diuretics are widely used in patients with heart and renal failure, as well as to treat hypertension and peripheral edema. However, there are no randomized, controlled trials (RCT) evaluating their long term safety, and several observ
Externí odkaz:
https://doaj.org/article/4a4af863b3b74d87bcbcd4c56301ff45
Autor:
Eli Skeie, Elin Strand, Eva R Pedersen, Bodil Bjørndal, Pavol Bohov, Rolf K Berge, Gard F T Svingen, Reinhard Seifert, Per M Ueland, Øivind Midttun, Arve Ulvik, Steinar Hustad, Christian A Drevon, Jesse F Gregory, Ottar Nygård
Publikováno v:
PLoS ONE, Vol 10, Iss 6, p e0129049 (2015)
The long-chain polyunsaturated fatty acids are considered to be of major health importance, and recent studies indicate that their endogenous metabolism is influenced by B-vitamin status and smoking habits. We investigated the associations of circula
Externí odkaz:
https://doaj.org/article/f46b58114f89485493be8a81ad3e4fcc