Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Reinhard Pregla"'
Autor:
Ulrich Kintscher, Jennifer Thomas, Vera Regitz-Zagrosek, Jens Fielitz, Reinhard Pregla, Michael Schupp, Roland Hetzer, Thomas Unger
Publikováno v:
European Journal of Heart Failure. 8:290-294
Background: The peroxisome proliferator-activated receptor alpha (PPARα) is a central regulator of myocardial fatty acid (FA) metabolism implicated in the pathogenesis of heart failure. Aims: To characterize PPARα regulation in human dilated cardio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0338a1d42b6de2b4830871588eebf05d
https://doi.org/10.1016/j.ejheart.2005.09.003
https://doi.org/10.1016/j.ejheart.2005.09.003
Autor:
Sarah Eder, Jörg Weiske, Peter Martus, Reinhard Pregla, Vera Regitz-Zagrosek, Johannes Nordmeyer, Shokoufeh Mahmoodzadeh, Elisabeth Ehler, Roland Hetzer, Otmar Huber
Publikováno v:
The FASEB Journal. 20:926-934
Clinical and animal studies suggest that estrogen receptors are involved in the development of myocardial hypertrophy and heart failure. In this study, we investigated whether human myocardial estrogen receptor alpha (ERalpha) expression, localizatio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd20566b04580ae7ec6b5b1b6c4158b4
https://doi.org/10.1096/fj.05-5148com
https://doi.org/10.1096/fj.05-5148com
Autor:
Christoph Gille, Andreas Ney, Stefan Mundlos, Alain J.P. Alix, Frank Barthel, Reinhard Pregla, Damian Counsell, Patrick Booms, Peter N. Robinson, Gautier Moroy, Gao Guo
Publikováno v:
Journal of Molecular and Cellular Cardiology. 40:234-246
Mutations in the gene for fibrillin-1 cause Marfan syndrome (MFS), a common hereditary disorder of connective tissue. Recent findings suggest that proteolysis, increased matrix metalloproteinase activity, and fragmentation of fibrillin-rich microfibr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32a9e531f93b435960f3acd2487fff8a
https://doi.org/10.1016/j.yjmcc.2005.11.009
https://doi.org/10.1016/j.yjmcc.2005.11.009
Publikováno v:
Regulatory Peptides. 124:195-201
Substance P and neurokinin A are regulatory peptides of the tachykinin family that influence many aspects of human airway function in health and diseases such as bronchial asthma or chronic obstructive pulmonary disease (COPD). Tachykinin-induced muc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abebccdeb02c640abd709f152389388e
https://doi.org/10.1016/j.regpep.2004.07.017
https://doi.org/10.1016/j.regpep.2004.07.017
Autor:
Roland Hetzer, Bernd-Joachim Thiele, Reinhard Pregla, Vera Regitz-Zagrosek, Anke Doller, Thilo Kähne
Publikováno v:
Circulation Research. 95:1058-1066
Collagen types I and III, coded by COL1A1/COL1A2 and COL3A1 genes, are the major fibrillar collagens produced by fibroblasts, including cardiac fibroblasts of the adult heart. Characteristic for different cardiomyopathies is a remodeling process asso
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a6282a5d9513e324119634d50d5cde3e
https://doi.org/10.1161/01.res.0000149166.33833.08
https://doi.org/10.1161/01.res.0000149166.33833.08
Autor:
Reinhard Pregla, Angelika Pletschacher, Peter N. Robinson, Stefan Mundlos, Frank Barthel, Andreas Ney, Dieter P. Reinhardt, Patrick Booms
Publikováno v:
Human Genetics. 116:51-61
The Marfan syndrome (MFS), a relatively common autosomal dominant disorder of connective tissue, is caused by mutations in the gene for fibrillin-1 (FBN1). Fibrillin-1 is the main component of the 10- to 12-nm microfibrils that together with elastin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::baf9f12f119afc47a280a529df661d7b
https://doi.org/10.1007/s00439-004-1194-7
https://doi.org/10.1007/s00439-004-1194-7
Autor:
Roland Hetzer, M Gutberlet, Harald Hausmann, Reinhard Pregla, Roland Felix, Rudolf Meyer, Holger Amthauer, Henryk Siniawski
Publikováno v:
European Journal of Cardio-Thoracic Surgery. 26:89-95
Objective: Coronary artery bypass grafting (CABG) in patients with endstage coronary disease (CAD) significantly improves symptoms and prolongs life expectancy. Left ventricular function is also improved in some patients, but not in others. Factors w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::71e1a091ab02eb34122072ee173fc7a9
https://doi.org/10.1016/j.ejcts.2004.03.029
https://doi.org/10.1016/j.ejcts.2004.03.029
Autor:
Reiner Buchhorn, Martin Hulpke-Wette, Jens Fielitz, Robert D. Ross, Reinhard Pregla, Wolfgang Ruschewski, Vera Regitz-Zagrosek, Roland Hetzer
Publikováno v:
Cardiology in the Young. 13:36-43
Background:Cardiac remodelling is now recognised as an important aspect of cardiovascular disease progression and is, therefore, emerging as a therapeutic target in cardiac failure due to different etiologies. Little is known about the influence of d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87ffe07f659c31f2b471f87064ca345e
https://doi.org/10.1017/s1047951103000076
https://doi.org/10.1017/s1047951103000076
Autor:
Reinhard Pregla, Oliver Donoso Mantke, Rudolf Meyer, Susanne Prösch, Roland Hetzer, Matthias Niedrig
Publikováno v:
Zeitschrift f�r Herz-, Thorax- und Gef��chirurgie. 17:9-16
Virale Infekte sind haufig als Ursache inflammatorischer Herzerkrankungen beschrieben worden. Diese konnen im Rahmen einer chronisch persistierenden Verlaufsform zu einer andauernden Herzinsuffizienz fuhren und eine Herztransplantation (HTx) erforder
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a847584551b32920e962cd7da7a0b72d
https://doi.org/10.1007/s00398-003-0371-7
https://doi.org/10.1007/s00398-003-0371-7
Autor:
Cornelia Schramm, Josefine Fuchs, Luitgard M. Neumann, Monika Palz, Stefanie Katzke, Angelika Pletschacher, Peter Lorenz, Patrick Booms, Seval Türkmen, Christa Leitner, Thomas Rosenberg, Flemming Skovby, Frank Tiecke, Peter N. Robinson, Reinhard Pregla, Christian Hagemeier
Publikováno v:
Human Mutation. 20:197-208
Mutations in the gene for fibrillin-1 (FBN1) cause Marfan syndrome (MFS), an autosomal dominant heritable disorder of connective tissue with prominent manifestations in the skeletal, ocular, and cardiovascular system. FBN1 mutations have also been id
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e23d47d684c972a53ed81ff3e35ed81
https://doi.org/10.1002/humu.10112
https://doi.org/10.1002/humu.10112