Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Reinhard Klinger"'
Publikováno v:
The Protein Journal. 29:127-135
Phosphoinositide 3-kinase gamma is a multifunctional enzyme with lipid and protein kinase activities that also acts as a scaffold protein in many diverse signalling processes. The enzyme contains five different domains, but their individual contribut
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8e83f531ce57e9db61e0d179649a91a8
https://doi.org/10.1007/s10930-010-9232-x
https://doi.org/10.1007/s10930-010-9232-x
Publikováno v:
Protein Engineering, Design and Selection. 15:521-527
It is a well known phenomenon that the occurrence of several distinct amino acids at the C-terminus of proteins is non-random. We have analysed all Saccharomyces cerevisiae proteins predicted by computer databases and found lysine to be the most freq
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::921fb7c59615733530be9584f0c80b55
https://doi.org/10.1093/protein/15.6.521
https://doi.org/10.1093/protein/15.6.521
Autor:
Elke Müller, Andrea Kauffmann-Zeh, J. Justin Hsuan, Horst Frunder, Reinhard Wetzker, Michael D. Waterfield, Michael J. Fry, Reinhard Klinger
Publikováno v:
European Journal of Biochemistry. 200:179-185
Two species of PtdIns 4-kinase with molecular masses of 50 kDa and 45 kDa were detected in human erythrocyte membranes using SDS/PAGE. These enzymes were purified to near homogeneity and found to display very similar enzymatic characteristics. The pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87e7f5445557cedea014b62764766e17
https://doi.org/10.1111/j.1432-1033.1991.tb21065.x
https://doi.org/10.1111/j.1432-1033.1991.tb21065.x
Publikováno v:
Journal of cancer research and clinical oncology. 130(12)
The tyrosine kinase receptor c-Kit (stem cell factor receptor, CD117) is a potential target for signal transduction therapy in different cancers. In this study we investigated c-Kit in CHRF cells, a megakaryoblastic cell line of Acute Myeloid Leukemi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3ddcf815304156e0c44040c2655fdbd9
https://pubmed.ncbi.nlm.nih.gov/15340843
https://pubmed.ncbi.nlm.nih.gov/15340843
Autor:
Matthias P. Wymann, Stefka Stoyanova, Theodor Hanck, Cornelia Kirsch, Reinhard Klinger, Ginette Bulgarelli-Leva, Reinhard Wetzker
Signalling via seven transmembrane helix receptors can lead to a massive increase in cellular PtdIns(3,4,5)P3, which is critical for the induction of various cell responses and is likely to be produced by a trimeric G-protein-sensitive phosphoinositi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5961e11cc89640e828bd65b7940f2d5
https://europepmc.org/articles/PMC1218456/
https://europepmc.org/articles/PMC1218456/
Autor:
U. Till, H. Frunder, Reinhard Klinger, E. Blume, K. Jaroszewicz, J. Günther, D. Zahn, J. G. Reich
Publikováno v:
European Journal of Biochemistry. 6:373-383
Experimental procedures and conditions are described for the determination of specific radioactivities of 16 different P-positions in 12 phosphorylated liver compounds after labelling in vivo with [32P]orthophosphate. These data are necessary for cal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::26752197a764e251ede5d99eb0674ea6
https://doi.org/10.1111/j.1432-1033.1968.tb00458.x
https://doi.org/10.1111/j.1432-1033.1968.tb00458.x
Publikováno v:
Biochimica et biophysica acta. 730(2)
Activation and inhibition of Ca2+-ATPase of calmodulin-depleted human erythrocyte membranes by oleic acid and a variety of other fatty acids have been measured. Low concentrations of oleic acid stimulate the enzyme activity, both in the presence and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22745a2e097448c1c12a64d4d57b2c6c
https://pubmed.ncbi.nlm.nih.gov/6133552
https://pubmed.ncbi.nlm.nih.gov/6133552
Autor:
Reinhard Wetzker, Reinhard Klinger, Frank-D. Böhmer, Elke Müller, Michael Scheven, Holger Hegewald, Richard Grosse
Publikováno v:
Biochimica et biophysica acta. 854(1)
Ca2+-ATPase was isolated from plasma membranes of Ehrlich ascites mammary carcinoma cells by means of calmodulin affinity chromatography. The purification procedure included removal of endogenous calmodulin from a Triton X-100 solubilizate of the mem
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bf5aa279a8eb52e02f142e996df152c
https://pubmed.ncbi.nlm.nih.gov/2935191
https://pubmed.ncbi.nlm.nih.gov/2935191
Publikováno v:
European journal of biochemistry. 11(3)
Within the first 30 sec after intravenous injection of [32P]Pi the P-flux was measured within the mononucleotide pool of the normal mouse liver. It is only in this short time interval that the dynamic phase of tracer kinetics is met, permitting prope
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f6522f1fe163d499bf493a8d455e007
https://pubmed.ncbi.nlm.nih.gov/5368339
https://pubmed.ncbi.nlm.nih.gov/5368339