Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Reinhard Karge"'
Publikováno v:
Molecules, Vol 2, Iss 11, Pp 176-179 (1997)
Phosphorus pentoxide is commonly used for the dehydration of heterocyclic carboxamides to the corresponding nitriles. In this report, the use of cyanuric chloride/N,N-disubstituted formamide for this reaction is described. The advantages of this proc
Externí odkaz:
https://doaj.org/article/9b2d216658c343bf99e70f784ed69bbf
Publikováno v:
CHIMIA, Vol 63, Iss 5 (2009)
In this contribution, the first examples of the catalytic highly enantioselective reduction of cyclic meso-anhydrides to lactones and of thioanhydrides to thiolactones are described. The N-benzyl protected key building blocks in the industrial synthe
Externí odkaz:
https://doaj.org/article/29f00b286f5c41e99b6bd9c39d92125a
Publikováno v:
Organic Process Research & Development. 22:1409-1418
3-(Bromoethynyl)azetidine is a highly energetic building block (decomposition energy up to −1800 J g–1) that was required in multikilogram quantities for the production of an API. The development of a four-step, fully telescoped, scalable sequenc
Autor:
Ulla Letinois, Reinhard Karge, Rinke Stoll, Florian Huffschmidt, Ralph Härter, Jan Schütz, Werner Bonrath
Publikováno v:
Organic Process Research & Development. 17:427-431
Pyrimidine synthesis starting from acrylonitrile has been known since the 1960s. The new Lewis acid-catalyzed condensation reaction allows the synthesis of 4-aminopyrimidines starting from the easily accessible chemical acrylonitrile without the need
Autor:
Andrey Gutnov, Marko Hapke, Reinhard Karge, Dmitry Redkin, Christine Fischer, Barbara Heller, Werner Bonrath
Publikováno v:
Synthesis. 2008:69-74
Chiral pyridyl alcohols have been prepared by developing a two-step approach that uses the asymmetric cyanation of aldehydes- to give cyanohydrins and subsequent [2+2+2]-cyclotri-merization reaction with acetylene.
Publikováno v:
Journal of Molecular Catalysis B: Enzymatic. :67-72
In this account, scope and limitations for the application of hydrolytic enzymes (lipases) to large-scale syntheses of economically important bulk products (vitamins) are discussed. In three case studies, biocatalytic alternatives were compared to
Publikováno v:
Journal of Chemical & Engineering Data. 48:48-51
Thermodynamic properties of different organic solvents dissolved in precursors of vitamin B5 are determined at infinitely dilute concentrations by using gas-liquid chromatography. From an analysis of experimental data and using the Peng-Robinson equa
Autor:
Reinhard Karge, Werner Bonrath
Publikováno v:
High Pressure Chemistry: Synthetic, Mechanistic, and Supercritical Applications
Publikováno v:
ChemInform. 42
Publikováno v:
Asymmetric Catalysis on Industrial Scale
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9e779253c67a27b40d187cfc568762af
https://doi.org/10.1002/9783527630639.ch3
https://doi.org/10.1002/9783527630639.ch3