Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Reinhard H. H. Neubert"'
Autor:
Reinhard H. H. Neubert, Cornelia Große, Yahya Mrestani, Matthias Brandsch, Beate Bretschneider, Sayed H. Auda, Ilka Knütter
Publikováno v:
Pharmaceuticals, Vol 2, Iss 3, Pp 184-193 (2009)
The effect of different metal ions on the intestinal transport and the antibacterial activity of cefadroxil [(6R,7R)-7-{[(2R)-2-amino-2-(4-hydroxyphenyl)acetyl]amino}-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid] was investiga
Externí odkaz:
https://doaj.org/article/9cb50c16ba2943b8b3ce9a009b46a6f4
Autor:
Jamal, Alyoussef Alkrad, Yousif Ali Almalki Ali, Almalki, Eman Zmaily, Dahmash, Loay Khaled, Hassouneh, Reinhard H H, Neubert
Publikováno v:
Skin pharmacology and physiology.
Heparin is a commonly used anticoagulant administered either by intravenous or subcutaneous injection for a systemic effect, or topically for the treatment of peripheral vascular disorders.This study aimed to formulate heparin in non-ionic colloidal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::4dc3b772fbf04b068530e16f30b6278b
https://pubmed.ncbi.nlm.nih.gov/36455520
https://pubmed.ncbi.nlm.nih.gov/36455520
The human skin provides a physiochemical and biological protective barrier to the body due to the unique structure of its outermost layer the stratum corneum. This layer consists of corneocytes and a multi-lamellar lipid matrix forming a composite, w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bc2cee97af5209e24be114380fe10f4e
https://doi.org/10.26434/chemrxiv-2022-73wjn
https://doi.org/10.26434/chemrxiv-2022-73wjn
Publikováno v:
Current problems in dermatology. 54
The pH value is identified as an essential determinant for the lipid synthesis in the stratum corneum (SC). The activity of the enzymes that catalyse the transformation of lipid precursors into ceramides, free fatty acids or cholesterol highly depend
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21cf36db792096206caea0161aefc2b3
https://pubmed.ncbi.nlm.nih.gov/30130772
https://pubmed.ncbi.nlm.nih.gov/30130772
Autor:
Adina, Eichner, Sören, Stahlberg, Stefan, Sonnenberger, Stefan, Lange, Bodo, Dobner, Andreas, Ostermann, Tobias E, Schrader, Thomas, Hauß, Annett, Schroeter, Daniel, Huster, Reinhard H H, Neubert
Publikováno v:
Biochimica et biophysica acta. Biomembranes. 1859(5)
The stratum corneum (SC) provides the main barrier properties in native skin. The barrier function is attributed to the intercellular lipids, forming continuous multilamellar membranes. In this study, SC lipid membranes in model ratios were enriched
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fe70f48d79d13657cff9534233936546
https://pubmed.ncbi.nlm.nih.gov/28132900
https://pubmed.ncbi.nlm.nih.gov/28132900
Publikováno v:
Journal of labelled compoundsradiopharmaceuticals. 59(12)
The synthesis of 12 deuterated ceramides with either a deuteration at the last carbon atom of the amide bound fatty acid or a perdeuterated fatty acid chain is described. The ceramides were prepared starting from sphingosine or phytosphingosine and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::241a1314787cff4590a4d2330625038c
https://pubmed.ncbi.nlm.nih.gov/27634543
https://pubmed.ncbi.nlm.nih.gov/27634543
Publikováno v:
Skin Pharmacology and Physiology. 25:200-207
In order to elucidate the mode of action of the lipophilic penetration enhancer isopropyl myristate (IPM) on a molecular scale, we investigated oriented quaternary stratum corneum (SC) lipid model membranes based on ceramide AP, cholesterol, palmitic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6507bfda76a6c10e4fd9d5c040d1a37
https://doi.org/10.1159/000338538
https://doi.org/10.1159/000338538
Publikováno v:
Journal of Non-Crystalline Solids. 355:2472-2479
The application of aerogels as drug delivery system was successfully demonstrated for silica aerogels previously. However, being biocompatible silica matrices are not biodegradable, which is a certain disadvantage for a number of pharmaceutically ori
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3fd1aaa670c36878fb6f2d622f6c5bd6
https://doi.org/10.1016/j.jnoncrysol.2009.08.038
https://doi.org/10.1016/j.jnoncrysol.2009.08.038
Autor:
Reinhard H. H. Neubert, Kateřina Vávrová, Mikhail A. Kiselev, Jarmila Zbytovská, P. Lessieur, Siegfried Wartewig
Publikováno v:
Colloids and Surfaces A: Physicochemical and Engineering Aspects. 351:30-37
This study evaluates the interactions of a model stratum corneum (SC) lipid system based on ceramide AP ( N -(2-hydroxystearoyl)phytosphingosine) with three selected permeation enhancers including urea, oleic acid (OA), and N -lauroylglycine lauryl e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc6c5c9d0a8045dac89008be1210c21e
https://doi.org/10.1016/j.colsurfa.2009.09.025
https://doi.org/10.1016/j.colsurfa.2009.09.025
Publikováno v:
Chromatographia. 70:581-584
A sensitive and simple liquid chromatography-mass spectrometry method was developed to determine the immunosuppressant tacrolimus in human skin samples after treatment with the commercially available ointment. Utilizing diffusion cell experiments acc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2ca352f275e97b136f1d1bac7a84c1c0
https://doi.org/10.1365/s10337-009-1157-1
https://doi.org/10.1365/s10337-009-1157-1