Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Reinhard H Dammann"'
Autor:
Aditi Mehta, Julio Cordero, Stephanie Dobersch, Addi J Romero‐Olmedo, Rajkumar Savai, Johannes Bodner, Cho‐Ming Chao, Ludger Fink, Ernesto Guzmán‐Díaz, Indrabahadur Singh, Gergana Dobreva, Ulf R Rapp, Stefan Günther, Olga N Ilinskaya, Saverio Bellusci, Reinhard H Dammann, Thomas Braun, Werner Seeger, Stefan Gattenlöhner, Achim Tresch, Andreas Günther, Guillermo Barreto
Publikováno v:
EMBO Molecular Medicine, Vol 8, Iss 12, Pp 1380-1389 (2016)
Abstract Lung cancer (LC) is the leading cause of cancer‐related deaths worldwide. Early LC diagnosis is crucial to reduce the high case fatality rate of this disease. In this case–control study, we developed an accurate LC diagnosis test using r
Externí odkaz:
https://doaj.org/article/6308c891f83e4cb5ada74d50ad1b0183
Autor:
Steffen Kiehl, Tobias Zimmermann, Rajkumar Savai, Soni S. Pullamsetti, Werner Seeger, Marek Bartkuhn, Reinhard H. Dammann
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-14 (2017)
Abstract Epigenetic deregulation is of importance in tumorigenesis. In particular CpG islands (CGI), are frequently hypermethylated. Here, genome-wide DNA-methylation profiles of 480,000 CpGs in lung cancer cells were generated. It was observed that
Externí odkaz:
https://doaj.org/article/345716730072453da0e6f7e9e2f438eb
Autor:
Antje M. Richter, Steffen Kiehl, Nicole Köger, Janina Breuer, Thorsten Stiewe, Reinhard H. Dammann
Publikováno v:
Clinical Epigenetics, Vol 9, Iss 1, Pp 1-12 (2017)
Abstract Background Lung cancer is the leading cause of cancer-related deaths with 1.8 million new cases each year and poor 5-year prognosis. Promoter hypermethylation of tumour suppressors leads to their inactivation and thereby can promote cancer d
Externí odkaz:
https://doaj.org/article/b953bc56758d461faa9e60f8787adfd2
Autor:
Michelle L. Woods, Astrid Weiss, Anna M. Sokol, Johannes Graumann, Thomas Boettger, Antje M. Richter, Ralph T. Schermuly, Reinhard H. Dammann
Publikováno v:
Cancer Gene Therapy. 29:1975-1987
Silencing of the Apoptosis associated Tyrosine Kinase gene (AATK) has been described in cancer. In our study, we specifically investigated the epigenetic inactivation of AATK in pancreatic adenocarcinoma, lower grade glioma, lung, breast, head, and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b38aca61393b028eeb449bbc38b9cce9
https://doi.org/10.1038/s41417-022-00513-x
https://doi.org/10.1038/s41417-022-00513-x
Autor:
Michelle L, Woods, Astrid, Weiss, Anna M, Sokol, Johannes, Graumann, Thomas, Boettger, Antje M, Richter, Ralph T, Schermuly, Reinhard H, Dammann
Publikováno v:
Cancer gene therapy.
Silencing of the Apoptosis associated Tyrosine Kinase gene (AATK) has been described in cancer. In our study, we specifically investigated the epigenetic inactivation of AATK in pancreatic adenocarcinoma, lower grade glioma, lung, breast, head, and n
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6a5c5d0afb1046ad165b26e8059ceb7c
https://pubmed.ncbi.nlm.nih.gov/35902728
https://pubmed.ncbi.nlm.nih.gov/35902728
Autor:
Miriam M, Küster, Marc A, Schneider, Antje M, Richter, Sarah, Richtmann, Hauke, Winter, Mark, Kriegsmann, Soni S, Pullamsetti, Thorsten, Stiewe, Rajkumar, Savai, Thomas, Muley, Reinhard H, Dammann
Publikováno v:
Cancers
Simple Summary Lung cancer is one of the most commonly diagnosed cancers worldwide and the most common cause of cancer-related deaths. During lung carcinogenesis, epigenetic alteration of tumor-related genes is a frequent event and especially silenci
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::69a2bda31dd894e2956d3c12cd24b388
https://pubmed.ncbi.nlm.nih.gov/33256112
https://pubmed.ncbi.nlm.nih.gov/33256112
Autor:
Adriana P, Jiménez, Annalena, Traum, Thomas, Boettger, Holger, Hackstein, Antje M, Richter, Reinhard H, Dammann
Publikováno v:
Oncotarget
The Hippo pathway regulates organ size, growth and comprises several tumor related factors, including the oncoprotein YAP1 and the tumor suppressor RASSF1A. RASSF1A is frequently epigenetically inactivated in cancer. In our study, we analyzed the eff
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fa282c382c3910fc30a6ff22b74ecaed
https://pubmed.ncbi.nlm.nih.gov/29179447
https://pubmed.ncbi.nlm.nih.gov/29179447
Autor:
Steffen, Kiehl, Stefanie C, Herkt, Antje M, Richter, Liesa, Fuhrmann, Nefertiti, El-Nikhely, Werner, Seeger, Rajkumar, Savai, Reinhard H, Dammann
Publikováno v:
Scientific Reports 4:6899 doi:10.1038/srep06899 http://www.nature.com/srep/2014/141104/srep06899/abs/srep06899.html#supplementary-information
Scientific Reports
Scientific Reports
Epigenetic silencing through promoter hypermethylation is an important hallmark for the inactivation of tumor-related genes in carcinogenesis. Here we identified the ATP-binding cassette sub-family B member 4 (ABCB4) as a novel epigenetically silence
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::681c4ebcd16d3835070b872578d0a7a0