Zobrazeno 1 - 10
of 92
pro vyhledávání: '"Reinhard Geiger"'
Publikováno v:
Analytical Biochemistry. 221:329-334
6-( N -Acetyl-L-phenylalanyl)-aminoluciferin as an example for a new class of highly sensitive bioluminogenic substrates that has been synthesized and characterized. These peptide derivatives can be used regarding to the peptide residue as highly sen
Publikováno v:
Liebigs Annalen der Chemie. 1994:365-368
Several new fluorogenic substrates for four proteases were synthesized by coupling the highly fluorescent 7-amino-4-methyl-2-quinolinone (AMeq) with appropriate amino acids and peptides. Compounds HCl · H-Ala-NH-Meq (1) and HCl · H-Leu-NH-Meq (2) a
Autor:
Reinhard Geiger, Maximilian Schneller
Publikováno v:
Biological Chemistry Hoppe-Seyler. 373:1095-1104
A highly effective method for the synthesis of neoglycoconjugates has been developed. The technique is based on two steps. First, a sulfhydryl group is introduced into the carbohydrate by reductive amination with cysteamine, and secondly the sulfhydr
Autor:
Matthias Siebeck, Hans Fritz, Marion Weis, Hans Hoffmann, Marianne Jochum, Michael Spannagl, Reinhard Geiger
Publikováno v:
American Review of Respiratory Disease. 142:782-788
We hypothesized that thrombin activation may play a prominent role in endotoxin-induced secondary organ failure, such as acute lung injury. To test this hypothesis, we administered a thrombin-specific inhibitor, recombinant hirudin, in endotoxemic pi
Publikováno v:
Nonradioactive Analysis of Biomolecules ISBN: 9783540646013
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::461a3794a2a307ab5bbad08977f99d3e
https://doi.org/10.1007/978-3-642-57206-7_21
https://doi.org/10.1007/978-3-642-57206-7_21
Publikováno v:
Immunoassay
This chapter provides an overview of the principles of bioluminescent light emission, bioluminescence immunoassay instrumentation, and bioluminescence enzyme immunoassays. Bioluminescence is a natural phenomenon found in many lower forms of life. Nat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ba1774f2e2401fc3eb69b90c7d0a4b5b
https://doi.org/10.1016/b978-012214730-2/50017-0
https://doi.org/10.1016/b978-012214730-2/50017-0
Publikováno v:
Journal of bioluminescence and chemiluminescence. 10(4)
The use of 6-(N-acetyl-L-phenylalanyl)-aminoluciferin as a novel substrate for alpha-chymotrypsin has been demonstrated. The kinetic parameters determined are KM = 0.38 mmol/L, kcat = 6.5 s-1 and kcat/kM = 17,100 (L/mol s). The test principle of the
Publikováno v:
Peptides 1994 ISBN: 9789072199218
Peptides 1994
Peptides 1994
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bf47c587a024d070566e8095163d7c49
https://doi.org/10.1007/978-94-011-1468-4_409
https://doi.org/10.1007/978-94-011-1468-4_409
Autor:
Reinhard Geiger, Werner Miska
Publikováno v:
Diagnostics in the Year 2000 ISBN: 9789401169783
Diagnostics in the Year 2000
Diagnostics in the Year 2000
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e69f1bf28a4d2f88a0488abddd0b9266
https://doi.org/10.1007/978-94-011-6976-9_7
https://doi.org/10.1007/978-94-011-6976-9_7
Publikováno v:
Biological chemistry Hoppe-Seyler. 373(12)
A derivative of D-luciferin, D-luciferin-O-beta-galactoside, was synthesized and used as highly sensitive substrate for beta-galactosidase. The substrate was physicochemically characterized. Enzymatic cleavage of the new compound by beta-galactosidas