Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Reinhard G. Kleineidam"'
Publikováno v:
Glycoconjugate Journal. 14:57-66
The inhibition of the α-2,6-sialyltransferase from rat liver, the α-2,3-sialyltransferase from porcine submandibular gland and of the galactosyltransferase from human milk were studied using monosaccharide-, nucleoside- and nucleotide-derivatives o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b147995a36daae86ff5b61719e20ef96
https://doi.org/10.1023/a:1018560931389
https://doi.org/10.1023/a:1018560931389
Autor:
Johannes F.G. Vliegenthart, Hans-Christian Siebert, Susanne Kruse, Jaap J. Beintema, Christine S. Wright, Robert Kaptein, Johannis P. Kamerling, Roland Schauer, Ukun M.S. Soedjanaatmadja, Hans-Joachim Gabius, Reinhard G. Kleineidam, Ann C. Rice, Petra J. W. Pouwels
Publikováno v:
Glycoconjugate Journal. 14:531-534
The side chains of tyrosine, tryptophan and histidine are able to produce CIDNP (Chemically Induced Dynamic Nuclear Polarization) signals after laser irradiation in the presence of a suitable radical pair-generating dye. Elicitation of such a respons
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7a444aeb0527a41ec97f07e7376cc994
https://doi.org/10.1023/a:1018572023153
https://doi.org/10.1023/a:1018572023153
Publikováno v:
Biological Chemistry Hoppe-Seyler. 376:569-576
Clostridium perfringens produces two sialidases, one of which has a molecular mass of 71 kDa and is secreted, while the 'small', 43 kDa isoenzyme remains in the cells. The secreted, higher molecular mass sialidases of two different clostridial strain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90a4ef0f3dc46ba445aac8a534f349ce
https://doi.org/10.1515/bchm3.1995.376.9.569
https://doi.org/10.1515/bchm3.1995.376.9.569
Publikováno v:
Glycoconjugate Journal. 10:116-119
Fractionation of horse liver homogenate by centrifugation into heavy membranes at 10,000 x g, microsomal fraction at 105,000 x g, and the supernatant revealed sialate 9-O-lactoyltransferase activity only in the latter fraction. For the enzyme assay,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4eda08d44e54564ee28811312c7d4cf
https://doi.org/10.1007/bf00731195
https://doi.org/10.1007/bf00731195
Publikováno v:
ChemInform. 22
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f85a5ec91ef0c4c99b10b9b631ad0ff2
https://doi.org/10.1002/chin.199117258
https://doi.org/10.1002/chin.199117258
Publikováno v:
Glycoconjugate Journal. 9:235-240
Three site-specific mutations were performed in two regions of a sialidase gene from Clostridium perfringens which are known to be conserved in bacterial sialidases. The mutant enzymes were expressed in Escherichia coli and, when measured with MU-Neu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8c1965d06f98cebe71eb832f2ca1848
https://doi.org/10.1007/bf00731135
https://doi.org/10.1007/bf00731135
Autor:
Reinhard G. Kleineidam, Michael Hartmann, Erwin Schreiner, R. Christian, Roland Schauer, Erich Zbiral
Publikováno v:
Biochemical Journal. 282:511-516
A series of neuraminic acid derivatives modified in the side chain or at C-3, C-4 or C-5 were tested as substrates of inhibitors of N-acetylneuraminate lyase (EC 4.1.3.3) from Clostridium perfringens. The results, together with Km and Ki values repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ca012b11bee568f0e81acecb0563e8c
https://doi.org/10.1042/bj2820511
https://doi.org/10.1042/bj2820511
Publikováno v:
Trends in Glycoscience and Glycotechnology. 4:263-268
シアリダーゼ (ノイラミニダーゼEC3.2.1.18)は、ガス壊疽菌である Clostridium により多量に産生され、哺乳動物組織の崩壊の一翼を担うことにより、その病原性に重要な役割を演ずる。シア
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::761a02b1f1f9db30500359b91f5a9cd7
https://doi.org/10.4052/tigg.4.263
https://doi.org/10.4052/tigg.4.263
Publikováno v:
Liebigs Annalen der Chemie. 1991:129-134
The peracetylated methyl ester 1 of N-acetylneuraminic acid was transformed into the oxazoline derivative 2, which was hydrogenated with Pd/C/H2 to give the 4-deoxy-Neu5Ac2en derivative 3. Acid cleavage of the oxazoline 2 by trifluoroacetic acid (THF
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3e6a29d9409a904a1f316dad6f5b4aa4
https://doi.org/10.1002/jlac.199119910124
https://doi.org/10.1002/jlac.199119910124
Publikováno v:
Biological Chemistry Hoppe-Seyler. 371:715-720
4-O-Acetylated, 7-O-acetylated, and 9-O-acetylated 4-methylumbelliferyl-alpha-N-acetyl-neuraminic acids (Neu4,5Ac2-MU, Neu5,7Ac2-MU, Neu5,9Ac2-MU) were tested as substrates of sialidases of Vibrio cholerae and of Clostridium perfringens. Both sialida
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1602e38bbaf35af564dbc65bff803c08
https://doi.org/10.1515/bchm3.1990.371.2.715
https://doi.org/10.1515/bchm3.1990.371.2.715